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The map label for this gene is fchA [H]

Identifier: 226948438

GI number: 226948438

Start: 1383944

End: 1384576

Strand: Direct

Name: fchA [H]

Synonym: CLM_1322

Alternate gene names: 226948438

Gene position: 1383944-1384576 (Clockwise)

Preceding gene: 226948437

Following gene: 226948439

Centisome position: 33.31

GC content: 30.33

Gene sequence:

>633_bases
GTGTTAGATAAAAGTTGTAAAGAATTTATAGATATTTTATCCTCTAAGGAACCTGTACCAGGTGGAGGCGGTGCTTGTGC
TTATGTAGGAGCTTTAGGTATGGCCTTAGGCAATATGGTAGCAAATCTTACTATAGGGAAGAAAAAATATAAAGATGTAG
AAGAGGATGTAAAAGAAATATTAAAAGAAGGAGAAGTGTTAATACAGAAATTAGAGGAATTAGTAAATAAAGATGCTGAA
GTATTTTATCCATTATCTAAAGCTTATGGATTACCTAAAAATACAGAAGAGGAAAAAGCATATAAAGATAAAGTTATGGA
AGAGGCATTATATAACGCTAGTTTAGTGCCGCTAGAAATAGCTAAATGTGCAGCAGAGACCATAGATCTTCATTATAAAT
TAGCTAAAATAGGAACTAGAATTGCTATAAGTGATGTAGGTGTAGGAGTGCTATTTTGTAAAACAGCACTAGAAGCTTCC
AAGTTAAATGTATATATAAATACTGGTATGATGAAAAATAATGATATAAAAAATTCGTTGAAAGAAGAAATCAACACCTT
AGTTTCTAAATATTCAACTAAGGCAGATAAAGTTTATAGTTATGTAGAAAATTTAATAAGGGGAAATGAATAA

Upstream 100 bases:

>100_bases
ATAATGTATAATATATATTAGTATTATAGAAAGTGTAATTAATTTAGCATAGTATTTACTATAATAAGAATAAATTAATA
AGGAAGGTAGGTGGATTTTT

Downstream 100 bases:

>100_bases
TGACTAAAATATTATATGGAAATGAAGTAGCTTTAAAAATAAAGGAAGATTTAAATTTAAGAATAGACAAATTAAAAGAA
AAAAATATAATACCTAAGTT

Product: putative methenyltetrahydrofolate cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEILKEGEVLIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKVMEEALYNASLVPLEIAKCAAETIDLHYKLAKIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLKEEINTLVSKYSTKADKVYSYVENLIRGNE

Sequences:

>Translated_210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEILKEGEVLIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKVMEEALYNASLVPLEIAKCAAETIDLHYKLAKIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLKEEINTLVSKYSTKADKVYSYVENLIRGNE
>Mature_210_residues
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEILKEGEVLIQKLEELVNKDAE
VFYPLSKAYGLPKNTEEEKAYKDKVMEEALYNASLVPLEIAKCAAETIDLHYKLAKIGTRIAISDVGVGVLFCKTALEAS
KLNVYINTGMMKNNDIKNSLKEEINTLVSKYSTKADKVYSYVENLIRGNE

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=167, Percent_Identity=26.9461077844311, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI11140815, Length=167, Percent_Identity=26.9461077844311, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 23114; Mature: 23114

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEI
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LKEGEVLIQKLEELVNKDAEVFYPLSKAYGLPKNTEEEKAYKDKVMEEALYNASLVPLEI
HHHHHHHHHHHHHHHCCCHHEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AKCAAETIDLHYKLAKIGTRIAISDVGVGVLFCKTALEASKLNVYINTGMMKNNDIKNSL
HHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH
KEEINTLVSKYSTKADKVYSYVENLIRGNE
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLDKSCKEFIDILSSKEPVPGGGGACAYVGALGMALGNMVANLTIGKKKYKDVEEDVKEI
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LKEGEVLIQKLEELVNKDAEVFYPLSKAYGLPKNTEEEKAYKDKVMEEALYNASLVPLEI
HHHHHHHHHHHHHHHCCCHHEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
AKCAAETIDLHYKLAKIGTRIAISDVGVGVLFCKTALEASKLNVYINTGMMKNNDIKNSL
HHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHH
KEEINTLVSKYSTKADKVYSYVENLIRGNE
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]