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The map label for this gene is wtpB [H]

Identifier: 226948382

GI number: 226948382

Start: 1321785

End: 1322657

Strand: Direct

Name: wtpB [H]

Synonym: CLM_1266

Alternate gene names: 226948382

Gene position: 1321785-1322657 (Clockwise)

Preceding gene: 226948381

Following gene: 226948383

Centisome position: 31.81

GC content: 27.03

Gene sequence:

>873_bases
GTGAAAGAAAAAATGAAACCTTATATATTATTATTGCCAGTTACAATAATAGTAGTTTCTATATTAGGAGTAGGAATAAT
AAATTGCCTAAGTCAAAGCTTAGGCTATTTCCCTACAGTGGGCTTGAATGAAATTACACTTAAATACTATAAAGAAGTAT
TAACTTCTAGGGAATTTGTAGAAGCTTTAAAATTTAGTTTATTTACCTGTACTCTATCTTCTTTGATAGCTGAATTTATT
GGTGTTGTTTTAGCTTATATTATATTTACTCATAAGAAGAGGAGTAAAATTTTAGATATCATATATAAGATACCTATAAT
AATACCTCATACTGTTGCAGTCTTACTTATTATAAATATGCTATCACAAAATGGAATATTGGCTAGAATATTATATAATT
TAGGATTAATAAGTTCTAGAAATATTTTTCCTAATCTTATAATGGATAAATGGGGCATAGGTATAATCATAACTTATGTA
TGGAAGGAGATACCTTTTATTATACTGGTTATCTATGCTGTATTAACTAATATAGATGAAAAAATGTGGCATCTTTCAAA
AACACTGGGGGCTAGCAAAACGCAAACTTTTTTTTATGTTATATTTCCTATGCTTGTGCCCTCTATTTTATCATCTTTTA
TAATAATCTTTGCTTTTTCTTTTGGAGCTTTTGAGGTACCTTATTTGTTAGGACCAACTACTCCAAAATCACTCTCAGTT
AAGGCATATATAGAATATTCTAATCCAGATTTAACCAATAGGCCTTATGCTATGGTAATAAACACTATACTTATAGTTAT
ATCAACCTTCTTAATAATTTTGTATAGAAAATCTTTGGATATTTTTAGAAAAAGAAATTTAGATAATAAATAG

Upstream 100 bases:

>100_bases
CAAAGTGAATTATTACCACACAGACTACCAGAGTTGCCAGCAGAATTAGTACCAATTATAGAAAAAATATGGCAGGAAAA
TATACCAGGAGATAAATAAA

Downstream 100 bases:

>100_bases
GAAAGGAAAATATTATAGATGAAAAATAAAAAAATAATTTCCAATATAATAATATATAGCTTCGCAATTTTCTTCCTATT
TCCTATAATAATATTATGTC

Product: ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKEKMKPYILLLPVTIIVVSILGVGIINCLSQSLGYFPTVGLNEITLKYYKEVLTSREFVEALKFSLFTCTLSSLIAEFI
GVVLAYIIFTHKKRSKILDIIYKIPIIIPHTVAVLLIINMLSQNGILARILYNLGLISSRNIFPNLIMDKWGIGIIITYV
WKEIPFIILVIYAVLTNIDEKMWHLSKTLGASKTQTFFYVIFPMLVPSILSSFIIIFAFSFGAFEVPYLLGPTTPKSLSV
KAYIEYSNPDLTNRPYAMVINTILIVISTFLIILYRKSLDIFRKRNLDNK

Sequences:

>Translated_290_residues
MKEKMKPYILLLPVTIIVVSILGVGIINCLSQSLGYFPTVGLNEITLKYYKEVLTSREFVEALKFSLFTCTLSSLIAEFI
GVVLAYIIFTHKKRSKILDIIYKIPIIIPHTVAVLLIINMLSQNGILARILYNLGLISSRNIFPNLIMDKWGIGIIITYV
WKEIPFIILVIYAVLTNIDEKMWHLSKTLGASKTQTFFYVIFPMLVPSILSSFIIIFAFSFGAFEVPYLLGPTTPKSLSV
KAYIEYSNPDLTNRPYAMVINTILIVISTFLIILYRKSLDIFRKRNLDNK
>Mature_290_residues
MKEKMKPYILLLPVTIIVVSILGVGIINCLSQSLGYFPTVGLNEITLKYYKEVLTSREFVEALKFSLFTCTLSSLIAEFI
GVVLAYIIFTHKKRSKILDIIYKIPIIIPHTVAVLLIINMLSQNGILARILYNLGLISSRNIFPNLIMDKWGIGIIITYV
WKEIPFIILVIYAVLTNIDEKMWHLSKTLGASKTQTFFYVIFPMLVPSILSSFIIIFAFSFGAFEVPYLLGPTTPKSLSV
KAYIEYSNPDLTNRPYAMVINTILIVISTFLIILYRKSLDIFRKRNLDNK

Specific function: Part of the ABC transporter complex wtpABC involved in molybdate/tungstate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1176

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=184, Percent_Identity=25.5434782608696, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787713, Length=150, Percent_Identity=28, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787369, Length=249, Percent_Identity=25.7028112449799, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33035; Mature: 33035

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure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EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]