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The map label for this gene is mucK [H]

Identifier: 226947255

GI number: 226947255

Start: 40398

End: 41507

Strand: Direct

Name: mucK [H]

Synonym: CLM_0048

Alternate gene names: 226947255

Gene position: 40398-41507 (Clockwise)

Preceding gene: 226947254

Following gene: 226947256

Centisome position: 0.97

GC content: 24.86

Gene sequence:

>1110_bases
ATGATATTAGTAGCAGTTTGTGATAGTACAAGAGGGATCTTTATCCCCATATTTAAAAATGAGTTTAATATAAATAATAC
TAAAATAGGATTGATGATTACTATAAGTACATTGGGATACACAGTATTTACATACTTAGGTGGCATATTGTGCCAAAAGA
AAGGGCAGAAGAGAGTTTATTCTATAGGACTTTTAATAATAAGTATATCTTTCTTACTATTAAATTTTACGCCTAATTAT
ATAATTCTTATTATTTTAATGTTTTTAATAAACGGAGGCCAAGCTTTCTTAGCTATATCTAGTAATACAATAATACCTAT
AATTTTTATAAGTTTTCAGGCTATAATAATGAATTTAGCTCATTTTAATTATGGAATGGGATTAGCTTTATCACAAAGGA
TTTCTGGTATGCTTTTGTATAGAGGTATAACTTGGAGAAGGATATACCTTTATTTATCAATTATAACTTTCATAGTGTAT
CTATTGTTATTTTTTATTAATATACCTGTGATTAATAAGTCAAAAGACGATAATAAATTAAAGTCGAAAGAAATTTTTAA
AGATAAGTTATTATATTTTTATATATTTGCATTAGGATTTTATGTATTTAGCGAAATAGCTACAGGAAATTGGTTCGTTA
ATTTAATGGAGAATGGATACAGATATAATAAAAATCAAAGTTCATATTATATATTTTTATTTTCAGCTTTATTTGCCTTA
GGGAGATTATTAGGGGGATTTTTAGTAGAAAAATTCAACTATATAAAGGCCGTATGCACATCTTTGGCTGTGGCTTTAAT
GATGTATACTATAGGTATAACATTAGGGCAAAAGGGGCTAATTTTAATATCATTATCTGGAATATTCTTTTCTATAGTAT
ATCCTACAGTAGTATTAACTATTAGCAAAGTATATTCCACTAATAGTTCTTATGTGACGGGAATAGTAGTAACCTTATCT
TCTTTTGTAAATATGATTATAAGTTTTTTAATGGGATATTTAAATGATTTAATAGGTATTTATACATCATATTATCTTAT
TCCTATAAGTTTATTTATTTCTTTAATGTTTATGTTTTTAATACACAAAAATATAAAAAAATTAGCTTAA

Upstream 100 bases:

>100_bases
AGAGATATAATTAAATAAAGTATATATTCATTAAATTTATTAGGGGGAATTAGCTATAAAGAATAAAAATTTTATATTGT
TGTTATATATTTTTTTAACT

Downstream 100 bases:

>100_bases
AATTTTTGACATATAGGGGAGAGGATTTATGAACAATAAATTTAAGGTAAGCATAGAATTAGCTAAAGGTACAGTAGATG
AATATATAGTTAAAGATATT

Product: major facilitator superfamily protein

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MILVAVCDSTRGIFIPIFKNEFNINNTKIGLMITISTLGYTVFTYLGGILCQKKGQKRVYSIGLLIISISFLLLNFTPNY
IILIILMFLINGGQAFLAISSNTIIPIIFISFQAIIMNLAHFNYGMGLALSQRISGMLLYRGITWRRIYLYLSIITFIVY
LLLFFINIPVINKSKDDNKLKSKEIFKDKLLYFYIFALGFYVFSEIATGNWFVNLMENGYRYNKNQSSYYIFLFSALFAL
GRLLGGFLVEKFNYIKAVCTSLAVALMMYTIGITLGQKGLILISLSGIFFSIVYPTVVLTISKVYSTNSSYVTGIVVTLS
SFVNMIISFLMGYLNDLIGIYTSYYLIPISLFISLMFMFLIHKNIKKLA

Sequences:

>Translated_369_residues
MILVAVCDSTRGIFIPIFKNEFNINNTKIGLMITISTLGYTVFTYLGGILCQKKGQKRVYSIGLLIISISFLLLNFTPNY
IILIILMFLINGGQAFLAISSNTIIPIIFISFQAIIMNLAHFNYGMGLALSQRISGMLLYRGITWRRIYLYLSIITFIVY
LLLFFINIPVINKSKDDNKLKSKEIFKDKLLYFYIFALGFYVFSEIATGNWFVNLMENGYRYNKNQSSYYIFLFSALFAL
GRLLGGFLVEKFNYIKAVCTSLAVALMMYTIGITLGQKGLILISLSGIFFSIVYPTVVLTISKVYSTNSSYVTGIVVTLS
SFVNMIISFLMGYLNDLIGIYTSYYLIPISLFISLMFMFLIHKNIKKLA
>Mature_369_residues
MILVAVCDSTRGIFIPIFKNEFNINNTKIGLMITISTLGYTVFTYLGGILCQKKGQKRVYSIGLLIISISFLLLNFTPNY
IILIILMFLINGGQAFLAISSNTIIPIIFISFQAIIMNLAHFNYGMGLALSQRISGMLLYRGITWRRIYLYLSIITFIVY
LLLFFINIPVINKSKDDNKLKSKEIFKDKLLYFYIFALGFYVFSEIATGNWFVNLMENGYRYNKNQSSYYIFLFSALFAL
GRLLGGFLVEKFNYIKAVCTSLAVALMMYTIGITLGQKGLILISLSGIFFSIVYPTVVLTISKVYSTNSSYVTGIVVTLS
SFVNMIISFLMGYLNDLIGIYTSYYLIPISLFISLMFMFLIHKNIKKLA

Specific function: Probable uptake of muconate [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41912; Mature: 41912

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVAVCDSTRGIFIPIFKNEFNINNTKIGLMITISTLGYTVFTYLGGILCQKKGQKRVY
CEEEEEECCCCCEEEEEECCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHH
SIGLLIISISFLLLNFTPNYIILIILMFLINGGQAFLAISSNTIIPIIFISFQAIIMNLA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCEEHHHHHHHHHHHHHHH
HFNYGMGLALSQRISGMLLYRGITWRRIYLYLSIITFIVYLLLFFINIPVINKSKDDNKL
HHCCCCCHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
KSKEIFKDKLLYFYIFALGFYVFSEIATGNWFVNLMENGYRYNKNQSSYYIFLFSALFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCEECCCCCCEEEHHHHHHHHH
GRLLGGFLVEKFNYIKAVCTSLAVALMMYTIGITLGQKGLILISLSGIFFSIVYPTVVLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
ISKVYSTNSSYVTGIVVTLSSFVNMIISFLMGYLNDLIGIYTSYYLIPISLFISLMFMFL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHKNIKKLA
HHHHHHHCC
>Mature Secondary Structure
MILVAVCDSTRGIFIPIFKNEFNINNTKIGLMITISTLGYTVFTYLGGILCQKKGQKRVY
CEEEEEECCCCCEEEEEECCCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHH
SIGLLIISISFLLLNFTPNYIILIILMFLINGGQAFLAISSNTIIPIIFISFQAIIMNLA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCEEHHHHHHHHHHHHHHH
HFNYGMGLALSQRISGMLLYRGITWRRIYLYLSIITFIVYLLLFFINIPVINKSKDDNKL
HHCCCCCHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
KSKEIFKDKLLYFYIFALGFYVFSEIATGNWFVNLMENGYRYNKNQSSYYIFLFSALFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCEECCCCCCEEEHHHHHHHHH
GRLLGGFLVEKFNYIKAVCTSLAVALMMYTIGITLGQKGLILISLSGIFFSIVYPTVVLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
ISKVYSTNSSYVTGIVVTLSSFVNMIISFLMGYLNDLIGIYTSYYLIPISLFISLMFMFL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHKNIKKLA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]