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The map label for this gene is yrvM [H]

Identifier: 226947254

GI number: 226947254

Start: 39611

End: 40315

Strand: Direct

Name: yrvM [H]

Synonym: CLM_0047

Alternate gene names: 226947254

Gene position: 39611-40315 (Clockwise)

Preceding gene: 226947253

Following gene: 226947255

Centisome position: 0.95

GC content: 28.79

Gene sequence:

>705_bases
ATGGAGAACTGGTTACAAAGAACTGAATTTTTAATAGGAAAAGAGGCTATAGAAAAATTAAACAAAAGTAAAATTGTGGT
TTTAGGTGTTGGAGGAGTTGGAAGTTTTGTAATAGAAGCATTAGTTAGATCTGGAGTAGGTAATATAACAATTGTTGATA
ATGATACAATAGATATAACTAATATAAACAGGCAAATCCACGCTAATTTAAATACTGTTGGAAAATCTAAAGTTGAGGTA
ATGAAAGAGAGAATACTATCTATAAATCCTAATTGTAATGTTAAAATCCATGAAGAATTTATAAATAAAGATAATATAAG
TGAATTAGTGGCTAAAGATACAGATTATGTTGTGGATGCTATAGATACGGCTTCTTCTAAAATATTAAGTATAGTATGGT
GTAATAAGAATAATATAAACATAATAAGTAGTATGGGTACAGCAAATAAATTGCACCCTACCAAATTAAGAATAGCTGAT
ATATATGATACTAAAGTATGTCCATTAGCTAAGATTATGAGATATGAACTTAGAAAGAGGAATATAAAAAGTTTGAAGGT
TTTATATTCAGAAGAAACTCCAATAAAAAATAATAATAGACCATTAAACGATAAAGGTAGGCCAACGCCAGCTAGTATAG
CTTTTGTCCCACCATGCGCTGGTCTTATAATAGCAGGAGAGGTAGTAAGAGATATAATTAAATAA

Upstream 100 bases:

>100_bases
CGGTTATATATAAGAATAGGGGTTTTTATAATTTTTGTAGATTAAATAATCGATTTTATTATAAAATAGTAGTAATTGAA
TAAAAATAAGGAGGATTAAA

Downstream 100 bases:

>100_bases
AGTATATATTCATTAAATTTATTAGGGGGAATTAGCTATAAAGAATAAAAATTTTATATTGTTGTTATATATTTTTTTAA
CTATGATATTAGTAGCAGTT

Product: thiF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MENWLQRTEFLIGKEAIEKLNKSKIVVLGVGGVGSFVIEALVRSGVGNITIVDNDTIDITNINRQIHANLNTVGKSKVEV
MKERILSINPNCNVKIHEEFINKDNISELVAKDTDYVVDAIDTASSKILSIVWCNKNNINIISSMGTANKLHPTKLRIAD
IYDTKVCPLAKIMRYELRKRNIKSLKVLYSEETPIKNNNRPLNDKGRPTPASIAFVPPCAGLIIAGEVVRDIIK

Sequences:

>Translated_234_residues
MENWLQRTEFLIGKEAIEKLNKSKIVVLGVGGVGSFVIEALVRSGVGNITIVDNDTIDITNINRQIHANLNTVGKSKVEV
MKERILSINPNCNVKIHEEFINKDNISELVAKDTDYVVDAIDTASSKILSIVWCNKNNINIISSMGTANKLHPTKLRIAD
IYDTKVCPLAKIMRYELRKRNIKSLKVLYSEETPIKNNNRPLNDKGRPTPASIAFVPPCAGLIIAGEVVRDIIK
>Mature_234_residues
MENWLQRTEFLIGKEAIEKLNKSKIVVLGVGGVGSFVIEALVRSGVGNITIVDNDTIDITNINRQIHANLNTVGKSKVEV
MKERILSINPNCNVKIHEEFINKDNISELVAKDTDYVVDAIDTASSKILSIVWCNKNNINIISSMGTANKLHPTKLRIAD
IYDTKVCPLAKIMRYELRKRNIKSLKVLYSEETPIKNNNRPLNDKGRPTPASIAFVPPCAGLIIAGEVVRDIIK

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=141, Percent_Identity=31.9148936170213, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI38045942, Length=123, Percent_Identity=30.8943089430894, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI38045944, Length=123, Percent_Identity=30.8943089430894, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789177, Length=180, Percent_Identity=39.4444444444444, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787048, Length=105, Percent_Identity=32.3809523809524, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87082356, Length=116, Percent_Identity=25, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71984476, Length=105, Percent_Identity=37.1428571428571, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540406, Length=132, Percent_Identity=31.0606060606061, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321790, Length=238, Percent_Identity=32.7731092436975, Blast_Score=122, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6322825, Length=189, Percent_Identity=39.1534391534392, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321903, Length=149, Percent_Identity=29.5302013422819, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24660640, Length=131, Percent_Identity=35.8778625954198, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582879, Length=118, Percent_Identity=27.9661016949153, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 26017; Mature: 26017

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENWLQRTEFLIGKEAIEKLNKSKIVVLGVGGVGSFVIEALVRSGVGNITIVDNDTIDIT
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCEEEEE
NINRQIHANLNTVGKSKVEVMKERILSINPNCNVKIHEEFINKDNISELVAKDTDYVVDA
ECCEEEECCCCCCCHHHHHHHHHHHEECCCCCCEEEHHHHCCCCCHHHHHHCCCCHHHHH
IDTASSKILSIVWCNKNNINIISSMGTANKLHPTKLRIADIYDTKVCPLAKIMRYELRKR
HHCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHC
NIKSLKVLYSEETPIKNNNRPLNDKGRPTPASIAFVPPCAGLIIAGEVVRDIIK
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MENWLQRTEFLIGKEAIEKLNKSKIVVLGVGGVGSFVIEALVRSGVGNITIVDNDTIDIT
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCEEEEECCEEEEE
NINRQIHANLNTVGKSKVEVMKERILSINPNCNVKIHEEFINKDNISELVAKDTDYVVDA
ECCEEEECCCCCCCHHHHHHHHHHHEECCCCCCEEEHHHHCCCCCHHHHHHCCCCHHHHH
IDTASSKILSIVWCNKNNINIISSMGTANKLHPTKLRIADIYDTKVCPLAKIMRYELRKR
HHCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHC
NIKSLKVLYSEETPIKNNNRPLNDKGRPTPASIAFVPPCAGLIIAGEVVRDIIK
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]