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The map label for this gene is ubiB [C]

Identifier: 226947239

GI number: 226947239

Start: 25991

End: 27589

Strand: Reverse

Name: ubiB [C]

Synonym: CLM_0029

Alternate gene names: 226947239

Gene position: 27589-25991 (Counterclockwise)

Preceding gene: 226947240

Following gene: 226947238

Centisome position: 0.66

GC content: 23.2

Gene sequence:

>1599_bases
ATGTACTTAAATTCTGTTCAAAGATTTAAAGAAATAATAAAAATATTAGCATTCTATGGTTTTGGTCATATAGTAGATTC
AAAATTTAACGAAGATAAAGCTCCTGAAAATTTAAGAAAAGCTTTTGAGAAATTAGGACCTACCTTTATAAAAATAGGCC
AAATATTAAGCACAAGACCTGATATATTATCAGCGCCCTATATAAAAGAATTATCAAAACTTCAAGACAGTGTACCTGAA
GATAATTTTAGTGATATAAACAAAATATTTTTTGAAGAATTTAATATATCCATAGAAGATGCTTTCTTAAATTTTAATAG
AAAACCTTTAGCTTCTGCTTCTATATCCCAAGTTTATTCTGCTAAACTTCATAATAATGAGGAAGTTATAGTAAAAATTC
AAAGGCCAGAAATAAAAGAAAAAATGAACATGGATTTAGCTATATTAAGAAAAATATTTACTCTTGGAAAAGTTAAAACC
TTTGATACATTAATAGACCCTAAAGAAGCTATAGATGAGCTAATAAATGCAACTAATTTAGAATTAGATTTTAATAATGA
AAAAGAAAATATTAAAAAATTTAAATACTTTAATAAAAATCTAAAATGTATTTATGTTCCTAATACTATAGATAAATACT
GTAGTAGCAAGATAATTACTATGGAAAAAATTCATGGTTTTAAGATAACCGATACAAAATCTTTAGATAAATTAAATTAT
GATAAAAAAGATGTAGCTCATAAATTAGCTATATCTATATTAAAACAAATTTTTGAAGATGGATTTTTTCATGGTGATCC
TCATCCTGGAAATATTTTTATATATGAAGGTAAAATATGTTATATAGATTTTGGAATAATGGGTACTCTATCATCTGATC
TAAAAAATTATTTAAATAAGGCTATGGTAGCTGTGGCTTTTAAAGATGTAGATAAACTTATATCTGTACTTTTGTCTATT
GGAATAAAAAAAGGTTATATAAATAAAAATAATTTATTTGAAGATATAAATTATTTATTTGATATTTATCTTTCTACTCC
TTTAAAGAATATAAAAATGTCCACCATGCTTCAAGAAGTCTTTGAATGTGCTAATCGTAATAATATTAGTTTACCTAAAG
AATTAACTATGCTCATAAGAAGCTTAATTATAATAGAAGGTATCTTAGAAAAAATAGATCCTAATATTCAAATATTAGAT
ATTGCGATTCCCTATGTAGAAAATAATAATAAAGTTAATTTTTTTAAAAATATTGATTTGGACGAATTAATATTAAATAG
TTATAAAACTGCAGAAGATTTATCAAAAATTCCTACTAAAACTGTTCAACTATTAAATAGTATTTTAAATGGTAGATCAA
AAATTCAACTTAATGTCAATAATCTAGATAGATCAATTAATGAATTAAACAAAATGATAAACAGAATAGTTTTTGCTTTA
ATAATATCCTCAATGATAATTGGTTTCTCTTTTATACTTAATTCTAACATTGGTCCTAAATTTTATGATATATCTATAAT
AGGAATATTAGGATACCTCATTGCAGCCTTTATGGGTTTTTGGCTTCTTATATCTATAATAAAATCTGGTAAATTATAA

Upstream 100 bases:

>100_bases
TAAAATTTCTCAATTAGAAAAATAATATTAATAAGCCCAACTAAGGTTAGGGCTTTTATTTATACTATAATATGGATAAA
ATTATCAGAGAGGTAGTAAA

Downstream 100 bases:

>100_bases
TCTATTTATGAATATTTCCGCTATTTCTATTAATTTATTGACATTTATAGCTAATTAAATAATAATTAATTTATCATATT
TTACTTAGAAAGAGGTTTTT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MYLNSVQRFKEIIKILAFYGFGHIVDSKFNEDKAPENLRKAFEKLGPTFIKIGQILSTRPDILSAPYIKELSKLQDSVPE
DNFSDINKIFFEEFNISIEDAFLNFNRKPLASASISQVYSAKLHNNEEVIVKIQRPEIKEKMNMDLAILRKIFTLGKVKT
FDTLIDPKEAIDELINATNLELDFNNEKENIKKFKYFNKNLKCIYVPNTIDKYCSSKIITMEKIHGFKITDTKSLDKLNY
DKKDVAHKLAISILKQIFEDGFFHGDPHPGNIFIYEGKICYIDFGIMGTLSSDLKNYLNKAMVAVAFKDVDKLISVLLSI
GIKKGYINKNNLFEDINYLFDIYLSTPLKNIKMSTMLQEVFECANRNNISLPKELTMLIRSLIIIEGILEKIDPNIQILD
IAIPYVENNNKVNFFKNIDLDELILNSYKTAEDLSKIPTKTVQLLNSILNGRSKIQLNVNNLDRSINELNKMINRIVFAL
IISSMIIGFSFILNSNIGPKFYDISIIGILGYLIAAFMGFWLLISIIKSGKL

Sequences:

>Translated_532_residues
MYLNSVQRFKEIIKILAFYGFGHIVDSKFNEDKAPENLRKAFEKLGPTFIKIGQILSTRPDILSAPYIKELSKLQDSVPE
DNFSDINKIFFEEFNISIEDAFLNFNRKPLASASISQVYSAKLHNNEEVIVKIQRPEIKEKMNMDLAILRKIFTLGKVKT
FDTLIDPKEAIDELINATNLELDFNNEKENIKKFKYFNKNLKCIYVPNTIDKYCSSKIITMEKIHGFKITDTKSLDKLNY
DKKDVAHKLAISILKQIFEDGFFHGDPHPGNIFIYEGKICYIDFGIMGTLSSDLKNYLNKAMVAVAFKDVDKLISVLLSI
GIKKGYINKNNLFEDINYLFDIYLSTPLKNIKMSTMLQEVFECANRNNISLPKELTMLIRSLIIIEGILEKIDPNIQILD
IAIPYVENNNKVNFFKNIDLDELILNSYKTAEDLSKIPTKTVQLLNSILNGRSKIQLNVNNLDRSINELNKMINRIVFAL
IISSMIIGFSFILNSNIGPKFYDISIIGILGYLIAAFMGFWLLISIIKSGKL
>Mature_532_residues
MYLNSVQRFKEIIKILAFYGFGHIVDSKFNEDKAPENLRKAFEKLGPTFIKIGQILSTRPDILSAPYIKELSKLQDSVPE
DNFSDINKIFFEEFNISIEDAFLNFNRKPLASASISQVYSAKLHNNEEVIVKIQRPEIKEKMNMDLAILRKIFTLGKVKT
FDTLIDPKEAIDELINATNLELDFNNEKENIKKFKYFNKNLKCIYVPNTIDKYCSSKIITMEKIHGFKITDTKSLDKLNY
DKKDVAHKLAISILKQIFEDGFFHGDPHPGNIFIYEGKICYIDFGIMGTLSSDLKNYLNKAMVAVAFKDVDKLISVLLSI
GIKKGYINKNNLFEDINYLFDIYLSTPLKNIKMSTMLQEVFECANRNNISLPKELTMLIRSLIIIEGILEKIDPNIQILD
IAIPYVENNNKVNFFKNIDLDELILNSYKTAEDLSKIPTKTVQLLNSILNGRSKIQLNVNNLDRSINELNKMINRIVFAL
IISSMIIGFSFILNSNIGPKFYDISIIGILGYLIAAFMGFWLLISIIKSGKL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=355, Percent_Identity=24.2253521126761, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI40254938, Length=259, Percent_Identity=28.1853281853282, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI217035081, Length=257, Percent_Identity=26.0700389105058, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI34147522, Length=303, Percent_Identity=23.4323432343234, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI27363457, Length=270, Percent_Identity=21.4814814814815, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI2367309, Length=497, Percent_Identity=28.3702213279678, Blast_Score=189, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17559152, Length=293, Percent_Identity=28.6689419795222, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI32565180, Length=302, Percent_Identity=26.158940397351, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555620, Length=286, Percent_Identity=24.4755244755245, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323282, Length=248, Percent_Identity=31.4516129032258, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325148, Length=497, Percent_Identity=24.5472837022133, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321319, Length=289, Percent_Identity=26.643598615917, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24662575, Length=283, Percent_Identity=29.6819787985866, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI22024280, Length=259, Percent_Identity=28.1853281853282, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI18859849, Length=295, Percent_Identity=24.406779661017, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 60941; Mature: 60941

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLNSVQRFKEIIKILAFYGFGHIVDSKFNEDKAPENLRKAFEKLGPTFIKIGQILSTRP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCC
DILSAPYIKELSKLQDSVPEDNFSDINKIFFEEFNISIEDAFLNFNRKPLASASISQVYS
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEHHHHCCCCCCCCHHHHHHHHH
AKLHNNEEVIVKIQRPEIKEKMNMDLAILRKIFTLGKVKTFDTLIDPKEAIDELINATNL
HHHCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCE
ELDFNNEKENIKKFKYFNKNLKCIYVPNTIDKYCSSKIITMEKIHGFKITDTKSLDKLNY
EEECCCCHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCEEHHHHCCEEECCCCCHHHCCC
DKKDVAHKLAISILKQIFEDGFFHGDPHPGNIFIYEGKICYIDFGIMGTLSSDLKNYLNK
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHHH
AMVAVAFKDVDKLISVLLSIGIKKGYINKNNLFEDINYLFDIYLSTPLKNIKMSTMLQEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FECANRNNISLPKELTMLIRSLIIIEGILEKIDPNIQILDIAIPYVENNNKVNFFKNIDL
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECCCH
DELILNSYKTAEDLSKIPTKTVQLLNSILNGRSKIQLNVNNLDRSINELNKMINRIVFAL
HHHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
IISSMIIGFSFILNSNIGPKFYDISIIGILGYLIAAFMGFWLLISIIKSGKL
HHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYLNSVQRFKEIIKILAFYGFGHIVDSKFNEDKAPENLRKAFEKLGPTFIKIGQILSTRP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCC
DILSAPYIKELSKLQDSVPEDNFSDINKIFFEEFNISIEDAFLNFNRKPLASASISQVYS
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEHHHHCCCCCCCCHHHHHHHHH
AKLHNNEEVIVKIQRPEIKEKMNMDLAILRKIFTLGKVKTFDTLIDPKEAIDELINATNL
HHHCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHCCCCE
ELDFNNEKENIKKFKYFNKNLKCIYVPNTIDKYCSSKIITMEKIHGFKITDTKSLDKLNY
EEECCCCHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCEEHHHHCCEEECCCCCHHHCCC
DKKDVAHKLAISILKQIFEDGFFHGDPHPGNIFIYEGKICYIDFGIMGTLSSDLKNYLNK
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHHH
AMVAVAFKDVDKLISVLLSIGIKKGYINKNNLFEDINYLFDIYLSTPLKNIKMSTMLQEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FECANRNNISLPKELTMLIRSLIIIEGILEKIDPNIQILDIAIPYVENNNKVNFFKNIDL
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCEEEEEECCCH
DELILNSYKTAEDLSKIPTKTVQLLNSILNGRSKIQLNVNNLDRSINELNKMINRIVFAL
HHHHHHHCCCHHHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
IISSMIIGFSFILNSNIGPKFYDISIIGILGYLIAAFMGFWLLISIIKSGKL
HHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA