| Definition | Listeria monocytogenes Clip81459, complete genome. |
|---|---|
| Accession | NC_012488 |
| Length | 2,912,690 |
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The map label for this gene is yvgN [H]
Identifier: 226225138
GI number: 226225138
Start: 2647881
End: 2648732
Strand: Reverse
Name: yvgN [H]
Synonym: Lm4b_02559
Alternate gene names: 226225138
Gene position: 2648732-2647881 (Counterclockwise)
Preceding gene: 226225139
Following gene: 226225136
Centisome position: 90.94
GC content: 40.26
Gene sequence:
>852_bases ATGAAAACAGTGAAATTAAACAATGGTGTAGAAGTACCTATTTTAGGATTTGGGACATATCAAATTACAGATGCTGCTGA AGCGGAACAAGCAGTAAAAGATGCGATTAAAACGGGCTATCGTCACATTGATACGGCGCAAAGTTATATGAATGAAGAAG CTGTAGGTCGCGGAATTGCGGCATCCGGCGTCGATCGCAAAGAACTATTCATTACGACAAAAATATGGGTGGAAAATGTA AGTTATAAAGGTGTTATGAGCTCATTTGACCGGTCTTTAAAACGTTTAGGGTTGGATTACATTGATTTGCTGCTAATTCA TCAACCTTTCAACGATGTATACGGGGCATGGATAGCGATGGAGGAATTACAAGCATCAGGAAAAATTAGAGCAATTGGCG TATCGAATTTTAGCCCGGATCGCGTAATTGACCTAGCTGCGTTCAATGAAGTAACTCCGCAAGTCAACCAAATTGAAGTT AATCCTTTCCAACAACAGGCAGCGAATCTAGCTGTTTTAAGAAAAGAAGGGGTTACAATAGAAGCATGGGCACCGTTTGC GGAAGGGAAAAATGATATTTTTAATAACCCAGTTTTAACGAAAATTGGTGCGAAATATGGAAAATCGGCCGCTCAAGTAA TTTTGCGTTGGCTAGTAGAGCAAGATATTATCGTCTTAGCTAAATCTGTAAAACCAGAAAGAATGGCGCAAAATCTGGCT ATATTTGATTTTGAATTGACGGAGGCAGATAAGGGAGAAATTGCCAGCCTAGATCAAGGGGAAAGCCAGTTCTTCTCACA TGCGGATCCAGAAATGGTGAAATGGATGGCTAGTCGCAAACTGAATGTATAA
Upstream 100 bases:
>100_bases TAGTCACATTGCGCAGTTTAAAGCTGGCGAATTAAATGCAGATAATGTAGAAAAATTATGGAAACGGGACAAATTTTAAA GATAAGAGGAGGATTTTCAA
Downstream 100 bases:
>100_bases ACGAAAAAAGGTTCTGCGTAAATGCAGAACCTTTTTTTATTTAACTATTGATGTCGATAGCTTTAATCCATCCTAGTGAA TTTTGTCTGTCTTTAAGATG
Product: oxidoreductase, aldo/keto reductase family
Products: NA
Alternate protein names: GR; Methylglyoxal reductase [H]
Number of amino acids: Translated: 283; Mature: 283
Protein sequence:
>283_residues MKTVKLNNGVEVPILGFGTYQITDAAEAEQAVKDAIKTGYRHIDTAQSYMNEEAVGRGIAASGVDRKELFITTKIWVENV SYKGVMSSFDRSLKRLGLDYIDLLLIHQPFNDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEV NPFQQQAANLAVLRKEGVTIEAWAPFAEGKNDIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLA IFDFELTEADKGEIASLDQGESQFFSHADPEMVKWMASRKLNV
Sequences:
>Translated_283_residues MKTVKLNNGVEVPILGFGTYQITDAAEAEQAVKDAIKTGYRHIDTAQSYMNEEAVGRGIAASGVDRKELFITTKIWVENV SYKGVMSSFDRSLKRLGLDYIDLLLIHQPFNDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEV NPFQQQAANLAVLRKEGVTIEAWAPFAEGKNDIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLA IFDFELTEADKGEIASLDQGESQFFSHADPEMVKWMASRKLNV >Mature_283_residues MKTVKLNNGVEVPILGFGTYQITDAAEAEQAVKDAIKTGYRHIDTAQSYMNEEAVGRGIAASGVDRKELFITTKIWVENV SYKGVMSSFDRSLKRLGLDYIDLLLIHQPFNDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEV NPFQQQAANLAVLRKEGVTIEAWAPFAEGKNDIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLA IFDFELTEADKGEIASLDQGESQFFSHADPEMVKWMASRKLNV
Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=293, Percent_Identity=30.3754266211604, Blast_Score=164, Evalue=1e-40, Organism=Homo sapiens, GI5174391, Length=293, Percent_Identity=30.3754266211604, Blast_Score=164, Evalue=1e-40, Organism=Homo sapiens, GI223468663, Length=292, Percent_Identity=32.1917808219178, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI310109920, Length=298, Percent_Identity=31.5436241610738, Blast_Score=159, Evalue=3e-39, Organism=Homo sapiens, GI310109922, Length=277, Percent_Identity=33.2129963898917, Blast_Score=159, Evalue=3e-39, Organism=Homo sapiens, GI45446745, Length=298, Percent_Identity=31.5436241610738, Blast_Score=159, Evalue=3e-39, Organism=Homo sapiens, GI4503285, Length=298, Percent_Identity=31.5436241610738, Blast_Score=159, Evalue=3e-39, Organism=Homo sapiens, GI5174695, Length=296, Percent_Identity=32.7702702702703, Blast_Score=157, Evalue=8e-39, Organism=Homo sapiens, GI93277124, Length=299, Percent_Identity=31.1036789297659, Blast_Score=157, Evalue=1e-38, Organism=Homo sapiens, GI5453543, Length=298, Percent_Identity=31.2080536912752, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI24497583, Length=304, Percent_Identity=30.9210526315789, Blast_Score=155, Evalue=6e-38, Organism=Homo sapiens, GI4502049, Length=290, Percent_Identity=33.448275862069, Blast_Score=148, Evalue=7e-36, Organism=Homo sapiens, GI24497585, Length=298, Percent_Identity=29.1946308724832, Blast_Score=145, Evalue=4e-35, Organism=Homo sapiens, GI300116273, Length=278, Percent_Identity=31.294964028777, Blast_Score=140, Evalue=2e-33, Organism=Homo sapiens, GI291291012, Length=288, Percent_Identity=30.2083333333333, Blast_Score=140, Evalue=2e-33, Organism=Homo sapiens, GI300116271, Length=282, Percent_Identity=31.2056737588652, Blast_Score=133, Evalue=2e-31, Organism=Homo sapiens, GI310109926, Length=114, Percent_Identity=45.6140350877193, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI207028673, Length=114, Percent_Identity=45.6140350877193, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI310109924, Length=153, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=4e-13, Organism=Escherichia coli, GI87082198, Length=261, Percent_Identity=41.3793103448276, Blast_Score=205, Evalue=3e-54, Organism=Escherichia coli, GI1786400, Length=252, Percent_Identity=39.2857142857143, Blast_Score=156, Evalue=1e-39, Organism=Escherichia coli, GI1788081, Length=279, Percent_Identity=28.3154121863799, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1789375, Length=335, Percent_Identity=25.3731343283582, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1788070, Length=316, Percent_Identity=23.4177215189873, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI48994888, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI87081735, Length=240, Percent_Identity=26.25, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17564128, Length=315, Percent_Identity=31.4285714285714, Blast_Score=170, Evalue=9e-43, Organism=Caenorhabditis elegans, GI17537077, Length=293, Percent_Identity=32.4232081911263, Blast_Score=162, Evalue=2e-40, Organism=Caenorhabditis elegans, GI71998625, Length=267, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=7e-39, Organism=Caenorhabditis elegans, GI17537079, Length=295, Percent_Identity=32.8813559322034, Blast_Score=157, Evalue=7e-39, Organism=Caenorhabditis elegans, GI17561298, Length=276, Percent_Identity=29.7101449275362, Blast_Score=155, Evalue=3e-38, Organism=Caenorhabditis elegans, GI17537075, Length=294, Percent_Identity=31.2925170068027, Blast_Score=154, Evalue=3e-38, Organism=Caenorhabditis elegans, GI17566692, Length=279, Percent_Identity=33.6917562724014, Blast_Score=154, Evalue=4e-38, Organism=Caenorhabditis elegans, GI17550248, Length=293, Percent_Identity=33.1058020477816, Blast_Score=152, Evalue=2e-37, Organism=Caenorhabditis elegans, GI17538386, Length=275, Percent_Identity=32, Blast_Score=151, Evalue=5e-37, Organism=Caenorhabditis elegans, GI17561300, Length=274, Percent_Identity=30.2919708029197, Blast_Score=133, Evalue=9e-32, Organism=Caenorhabditis elegans, GI17552492, Length=263, Percent_Identity=29.277566539924, Blast_Score=132, Evalue=2e-31, Organism=Caenorhabditis elegans, GI17562292, Length=278, Percent_Identity=26.6187050359712, Blast_Score=122, Evalue=1e-28, Organism=Saccharomyces cerevisiae, GI6320576, Length=288, Percent_Identity=37.1527777777778, Blast_Score=192, Evalue=4e-50, Organism=Saccharomyces cerevisiae, GI6324694, Length=293, Percent_Identity=35.1535836177474, Blast_Score=181, Evalue=1e-46, Organism=Saccharomyces cerevisiae, GI6322556, Length=280, Percent_Identity=33.5714285714286, Blast_Score=154, Evalue=1e-38, Organism=Saccharomyces cerevisiae, GI6319625, Length=295, Percent_Identity=32.2033898305085, Blast_Score=132, Evalue=5e-32, Organism=Saccharomyces cerevisiae, GI6320079, Length=275, Percent_Identity=35.6363636363636, Blast_Score=132, Evalue=6e-32, Organism=Saccharomyces cerevisiae, GI6321896, Length=304, Percent_Identity=31.25, Blast_Score=131, Evalue=9e-32, Organism=Drosophila melanogaster, GI24644950, Length=299, Percent_Identity=36.7892976588629, Blast_Score=182, Evalue=2e-46, Organism=Drosophila melanogaster, GI24663317, Length=291, Percent_Identity=38.1443298969072, Blast_Score=182, Evalue=3e-46, Organism=Drosophila melanogaster, GI221378297, Length=319, Percent_Identity=34.4827586206897, Blast_Score=174, Evalue=5e-44, Organism=Drosophila melanogaster, GI21356425, Length=290, Percent_Identity=35.5172413793103, Blast_Score=172, Evalue=3e-43, Organism=Drosophila melanogaster, GI24657054, Length=289, Percent_Identity=35.9861591695502, Blast_Score=168, Evalue=3e-42, Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=33.7931034482759, Blast_Score=166, Evalue=2e-41, Organism=Drosophila melanogaster, GI20129731, Length=284, Percent_Identity=35.2112676056338, Blast_Score=153, Evalue=1e-37, Organism=Drosophila melanogaster, GI24662789, Length=289, Percent_Identity=32.8719723183391, Blast_Score=145, Evalue=3e-35, Organism=Drosophila melanogaster, GI24662781, Length=283, Percent_Identity=35.3356890459364, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI281366140, Length=254, Percent_Identity=31.1023622047244, Blast_Score=131, Evalue=6e-31, Organism=Drosophila melanogaster, GI24662785, Length=276, Percent_Identity=34.0579710144928, Blast_Score=124, Evalue=5e-29,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.283 [H]
Molecular weight: Translated: 31442; Mature: 31442
Theoretical pI: Translated: 4.93; Mature: 4.93
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTVKLNNGVEVPILGFGTYQITDAAEAEQAVKDAIKTGYRHIDTAQSYMNEEAVGRGIA CCEEECCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCH ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPFNDVYGAWIAM HCCCCCHHEEEEEEHEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHH EELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQAANLAVLRKEGVTI HHHHCCCCEEEEEECCCCCCCEEEEHHHHCCCCCCCEEECCHHHHHHHCEEEEEECCCEE EAWAPFAEGKNDIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLA EECCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCE IFDFELTEADKGEIASLDQGESQFFSHADPEMVKWMASRKLNV EEEEEECCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCC >Mature Secondary Structure MKTVKLNNGVEVPILGFGTYQITDAAEAEQAVKDAIKTGYRHIDTAQSYMNEEAVGRGIA CCEEECCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCH ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPFNDVYGAWIAM HCCCCCHHEEEEEEHEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHH EELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQAANLAVLRKEGVTI HHHHCCCCEEEEEECCCCCCCEEEEHHHHCCCCCCCEEECCHHHHHHHCEEEEEECCCEE EAWAPFAEGKNDIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLA EECCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCE IFDFELTEADKGEIASLDQGESQFFSHADPEMVKWMASRKLNV EEEEEECCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9639930; 9384377 [H]