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The map label for this gene is murZ

Identifier: 226225099

GI number: 226225099

Start: 2599566

End: 2600837

Strand: Reverse

Name: murZ

Synonym: Lm4b_02520

Alternate gene names: 226225099

Gene position: 2600837-2599566 (Counterclockwise)

Preceding gene: 226225100

Following gene: 226225098

Centisome position: 89.29

GC content: 40.8

Gene sequence:

>1272_bases
GTGACGGATAAATTGATTATTCGAGGCGGTAAAAAATTAGCTGGTACTTTGCAAGTGGATGGCGCAAAAAATAGTGCGGT
GGCATTAATTCCAGCGGCAATTTTGGCGGAGTCTGAAGTGGTTTTAGAAGGTTTACCAGATATTTCGGATGTTCACACAC
TTTATAATATTTTAGAAGAGCTTGGCGGCACGGTTCGCTATGATAATAAAACAGCAGTTATTGATCCAACAGATATGATT
TCTATGCCACTTCCATCGGGAAATGTGAAGAAATTACGTGCGTCCTATTATTTAATGGGTGCAATGTTAGGCCGATTTAA
AAAAGCGGTTATTGGACTTCCAGGCGGTTGTTACTTAGGGCCACGTCCAATCGACCAACATATAAAAGGTTTTGAAGCAT
TAGGCGCAAAAGTAACGAACGAGCAAGGTGCGATTTATTTGCGTGCCGATGAACTCAAAGGTGCACGGATTTATTTAGAT
GTTGTAAGTGTTGGAGCGACAATCAATATCATGCTAGCGGCTGTTCGTGCAAAAGGAAAAACGGTTATCGAAAATGCAGC
AAAAGAGCCAGAAATTATTGATGTTGCAACGCTTTTAACAAATATGGGAGCAATTATTAAAGGTGCAGGAACTGATACTA
TTCGAATCACTGGGGTAGAGCATTTACATGGTTGTCATCATACAATTATTCCAGACCGAATCGAAGCAGGGACATTCATG
GTACTTGCAGCAGCTTCTGGGAAGGGAGTACGAATCGAAAATGTTATTCCTACCCATTTAGAAGGAATCATTGCAAAGCT
CACAGAAATGGGCGTTCCAATGGATATCGAAGAAGATGCTATTTTTGTTGGGGAAGTAGAAAAAATAAAAAAAGTAGATA
TTAAAACTTACGCTTATCCAGGCTTCCCAACGGACTTACAACAACCGTTAACTGCTCTTTTAACACGTGCGGAAGGTAGT
AGTGTCATCACTGATACAATTTATCCAAGCCGTTTTAAACACATTGCGGAGATTGAACGAATGGGCGGTAAGTTTAAACT
TGAAGGTCGTTCGGCTGTCATAAATGGTCCTGTGCAACTTCAAGGTTCTAAAGTGACAGCGACAGATTTACGCGCCGGTG
CAGCGCTTGTAATTGCAGCACTTTTAGCTGACGGAGAAACTGAAATTCACGGGGTGGAACATATCGAACGTGGTTACAGT
AAGATTATTGAAAAATTATCTGCTATTGGCGCAAATATTACTCGTAGTAGCGCAGCAGAAACAAAATTATAA

Upstream 100 bases:

>100_bases
TAATGTTCCCAGCTTTTTAGGGAAAGCATTTCTTGCAAAGTAAAACAAATTAATGGATAATGAAACAGTATTACATGCTT
CAAGAAAGAAGGGTACATTT

Downstream 100 bases:

>100_bases
AAAATGAGGCTGAACGAATCAAGTCGTTTCAGCCTTCCCTCTAAATCCCTCCATTATCATTTATTCCTAAATACTATTTA
TTAACTCAAAAAGGTGGTAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTDKLIIRGGKKLAGTLQVDGAKNSAVALIPAAILAESEVVLEGLPDISDVHTLYNILEELGGTVRYDNKTAVIDPTDMI
SMPLPSGNVKKLRASYYLMGAMLGRFKKAVIGLPGGCYLGPRPIDQHIKGFEALGAKVTNEQGAIYLRADELKGARIYLD
VVSVGATINIMLAAVRAKGKTVIENAAKEPEIIDVATLLTNMGAIIKGAGTDTIRITGVEHLHGCHHTIIPDRIEAGTFM
VLAAASGKGVRIENVIPTHLEGIIAKLTEMGVPMDIEEDAIFVGEVEKIKKVDIKTYAYPGFPTDLQQPLTALLTRAEGS
SVITDTIYPSRFKHIAEIERMGGKFKLEGRSAVINGPVQLQGSKVTATDLRAGAALVIAALLADGETEIHGVEHIERGYS
KIIEKLSAIGANITRSSAAETKL

Sequences:

>Translated_423_residues
MTDKLIIRGGKKLAGTLQVDGAKNSAVALIPAAILAESEVVLEGLPDISDVHTLYNILEELGGTVRYDNKTAVIDPTDMI
SMPLPSGNVKKLRASYYLMGAMLGRFKKAVIGLPGGCYLGPRPIDQHIKGFEALGAKVTNEQGAIYLRADELKGARIYLD
VVSVGATINIMLAAVRAKGKTVIENAAKEPEIIDVATLLTNMGAIIKGAGTDTIRITGVEHLHGCHHTIIPDRIEAGTFM
VLAAASGKGVRIENVIPTHLEGIIAKLTEMGVPMDIEEDAIFVGEVEKIKKVDIKTYAYPGFPTDLQQPLTALLTRAEGS
SVITDTIYPSRFKHIAEIERMGGKFKLEGRSAVINGPVQLQGSKVTATDLRAGAALVIAALLADGETEIHGVEHIERGYS
KIIEKLSAIGANITRSSAAETKL
>Mature_422_residues
TDKLIIRGGKKLAGTLQVDGAKNSAVALIPAAILAESEVVLEGLPDISDVHTLYNILEELGGTVRYDNKTAVIDPTDMIS
MPLPSGNVKKLRASYYLMGAMLGRFKKAVIGLPGGCYLGPRPIDQHIKGFEALGAKVTNEQGAIYLRADELKGARIYLDV
VSVGATINIMLAAVRAKGKTVIENAAKEPEIIDVATLLTNMGAIIKGAGTDTIRITGVEHLHGCHHTIIPDRIEAGTFMV
LAAASGKGVRIENVIPTHLEGIIAKLTEMGVPMDIEEDAIFVGEVEKIKKVDIKTYAYPGFPTDLQQPLTALLTRAEGSS
VITDTIYPSRFKHIAEIERMGGKFKLEGRSAVINGPVQLQGSKVTATDLRAGAALVIAALLADGETEIHGVEHIERGYSK
IIEKLSAIGANITRSSAAETKL

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=415, Percent_Identity=43.3734939759036, Blast_Score=336, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45057; Mature: 44926

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKLIIRGGKKLAGTLQVDGAKNSAVALIPAAILAESEVVLEGLPDISDVHTLYNILEE
CCCCEEEECCCCEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHH
LGGTVRYDNKTAVIDPTDMISMPLPSGNVKKLRASYYLMGAMLGRFKKAVIGLPGGCYLG
HCCEEEECCEEEEECCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PRPIDQHIKGFEALGAKVTNEQGAIYLRADELKGARIYLDVVSVGATINIMLAAVRAKGK
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEEEHHHCCC
TVIENAAKEPEIIDVATLLTNMGAIIKGAGTDTIRITGVEHLHGCHHTIIPDRIEAGTFM
HHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEECHHHHCCCCCCCCCCCCCCCEEE
VLAAASGKGVRIENVIPTHLEGIIAKLTEMGVPMDIEEDAIFVGEVEKIKKVDIKTYAYP
EEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHEECEEEEECC
GFPTDLQQPLTALLTRAEGSSVITDTIYPSRFKHIAEIERMGGKFKLEGRSAVINGPVQL
CCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCEEEECCCEEEECCCEEE
QGSKVTATDLRAGAALVIAALLADGETEIHGVEHIERGYSKIIEKLSAIGANITRSSAAE
ECCEEEHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TKL
CCC
>Mature Secondary Structure 
TDKLIIRGGKKLAGTLQVDGAKNSAVALIPAAILAESEVVLEGLPDISDVHTLYNILEE
CCCEEEECCCCEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHH
LGGTVRYDNKTAVIDPTDMISMPLPSGNVKKLRASYYLMGAMLGRFKKAVIGLPGGCYLG
HCCEEEECCEEEEECCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PRPIDQHIKGFEALGAKVTNEQGAIYLRADELKGARIYLDVVSVGATINIMLAAVRAKGK
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEEEHHHCCC
TVIENAAKEPEIIDVATLLTNMGAIIKGAGTDTIRITGVEHLHGCHHTIIPDRIEAGTFM
HHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEEECHHHHCCCCCCCCCCCCCCCEEE
VLAAASGKGVRIENVIPTHLEGIIAKLTEMGVPMDIEEDAIFVGEVEKIKKVDIKTYAYP
EEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHEECEEEEECC
GFPTDLQQPLTALLTRAEGSSVITDTIYPSRFKHIAEIERMGGKFKLEGRSAVINGPVQL
CCCHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCEEEECCCEEEECCCEEE
QGSKVTATDLRAGAALVIAALLADGETEIHGVEHIERGYSKIIEKLSAIGANITRSSAAE
ECCEEEHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
TKL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]