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The map label for this gene is tdk [H]

Identifier: 226225092

GI number: 226225092

Start: 2593254

End: 2593829

Strand: Reverse

Name: tdk [H]

Synonym: Lm4b_02513

Alternate gene names: 226225092

Gene position: 2593829-2593254 (Counterclockwise)

Preceding gene: 226225093

Following gene: 226225091

Centisome position: 89.05

GC content: 34.03

Gene sequence:

>576_bases
ATGGCACAATTATTTTTCCGTTATGGTTCCATGAATAGTGGGAAAACCATTGAAATTCTAAAAGTCGCACATAATTATGA
AGAACAAAATAAAACAGTGGCTATCTTTACTTCAGGTATTGACGATAGAGACCAAGTTGGCTTCATTTCAAGTCGAATTG
GACTGAAACGAGAAGCAACTCCTATTTTTAGTGACACAAATATTTTTGAAATCGTAGCGAATATTAAACCAAAACCAAAT
TGCGTTCTTTTAGATGAATCGCAATTTCTAGAAAAAGAACACGTATTTCAGTTAGCGAAAATTGTGGATGAATTAAATAT
CCCAGTTATTGCTTATGGTTTAAAAAATGATTTTCGAAATGAATTATTCGAAGGCTCGAAATACTTGCTATTATATGCAG
ATAAACTAGAAGAAATGAAAACAATTTGCTGGTTTTGTGCTAAAAAGGCAACGATGGTTCTGCGCGTGGATGACAAAGGA
AAACCAGTTTATACAGGTGAACAAATTATGATTGGCGGAAATGACCACTATTACCCTGTGTGTCGCAAATGTCATGCCAA
TCCACCAATAAAATAA

Upstream 100 bases:

>100_bases
GCCCCTATGCGGCGTAGCTTTTTTTAACTATATGTCCCAATTTGTGCCGCTCTATGATAAAATAGGAAAAGAGTTTATAA
AGTTAAAGGGAGCGGTCTTA

Downstream 100 bases:

>100_bases
TTAAAAGAGGTGTTGAAATACAATGTATGATCGATTACAGGCGGTGGAAGACCGTTATGATGAACTAAATGAGTTATTAA
GTGATCCAGATGTAGTATCG

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MAQLFFRYGSMNSGKTIEILKVAHNYEEQNKTVAIFTSGIDDRDQVGFISSRIGLKREATPIFSDTNIFEIVANIKPKPN
CVLLDESQFLEKEHVFQLAKIVDELNIPVIAYGLKNDFRNELFEGSKYLLLYADKLEEMKTICWFCAKKATMVLRVDDKG
KPVYTGEQIMIGGNDHYYPVCRKCHANPPIK

Sequences:

>Translated_191_residues
MAQLFFRYGSMNSGKTIEILKVAHNYEEQNKTVAIFTSGIDDRDQVGFISSRIGLKREATPIFSDTNIFEIVANIKPKPN
CVLLDESQFLEKEHVFQLAKIVDELNIPVIAYGLKNDFRNELFEGSKYLLLYADKLEEMKTICWFCAKKATMVLRVDDKG
KPVYTGEQIMIGGNDHYYPVCRKCHANPPIK
>Mature_190_residues
AQLFFRYGSMNSGKTIEILKVAHNYEEQNKTVAIFTSGIDDRDQVGFISSRIGLKREATPIFSDTNIFEIVANIKPKPNC
VLLDESQFLEKEHVFQLAKIVDELNIPVIAYGLKNDFRNELFEGSKYLLLYADKLEEMKTICWFCAKKATMVLRVDDKGK
PVYTGEQIMIGGNDHYYPVCRKCHANPPIK

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=185, Percent_Identity=49.7297297297297, Blast_Score=194, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21850; Mature: 21718

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLFFRYGSMNSGKTIEILKVAHNYEEQNKTVAIFTSGIDDRDQVGFISSRIGLKREAT
CCEEEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCC
PIFSDTNIFEIVANIKPKPNCVLLDESQFLEKEHVFQLAKIVDELNIPVIAYGLKNDFRN
CCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
ELFEGSKYLLLYADKLEEMKTICWFCAKKATMVLRVDDKGKPVYTGEQIMIGGNDHYYPV
HHHCCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCEEEECCCCCCCHH
CRKCHANPPIK
HHHCCCCCCCC
>Mature Secondary Structure 
AQLFFRYGSMNSGKTIEILKVAHNYEEQNKTVAIFTSGIDDRDQVGFISSRIGLKREAT
CEEEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCC
PIFSDTNIFEIVANIKPKPNCVLLDESQFLEKEHVFQLAKIVDELNIPVIAYGLKNDFRN
CCCCCCCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHH
ELFEGSKYLLLYADKLEEMKTICWFCAKKATMVLRVDDKGKPVYTGEQIMIGGNDHYYPV
HHHCCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCEEEECCCCCCCHH
CRKCHANPPIK
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]