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The map label for this gene is fabZ

Identifier: 226225072

GI number: 226225072

Start: 2574990

End: 2575424

Strand: Reverse

Name: fabZ

Synonym: Lm4b_02493

Alternate gene names: 226225072

Gene position: 2575424-2574990 (Counterclockwise)

Preceding gene: 226225073

Following gene: 226225071

Centisome position: 88.42

GC content: 37.7

Gene sequence:

>435_bases
ATGTTAGATATTAAGAAAATCAAAGAGATTTTGCCTCATCGTTATCCATTTTTGTTAGTAGATAGAGTTATTTCTGTTGA
AGAAGGCAAAAAAGTTACCGCTATTAAGAATGTAACAGCAAATGAAGAATTTTTTAACGGGCACTTTCCTGAGTATCCTG
TAATGCCAGGAGTTTTAATAGTGGAAGCTCTAGCGCAAACTAGTGGAATTGCAATGATGCAGAGTGAAGCAAATAAAGGT
AAAATTGGTTTATTTGCTGGAATTGATGGTTGCCGATTTAAACGTCAAGTTGTTCCGGGGGACCAACTCTTGCTTGAGGC
TGAAATAACTCGGATGAGGGGCGCGATTGCAAAAGCAAAAGTCAAAGCAACTGTAGAAGGCGATTTGGTTTGTGAAGCTG
AAATTATGTTTGCCTTATCAGACCTACCTAAATAA

Upstream 100 bases:

>100_bases
AATCCTTTAGATGTAGTGGCACTTGGTACCGGCATTTTACTTGACTCACTTACAAATAAAAAGCGTAATAGATTCTAAAT
GTGAATTTTGGGGGATGTAT

Downstream 100 bases:

>100_bases
AAAGATTAGCACTGAGGTCCAAATGGGTTTTAGTGCTTTTTTCATGTTCTCAGAATAACATTGGTTAAAAATTTTTTCAA
AGTACTAAAATGATGCTTTG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLDIKKIKEILPHRYPFLLVDRVISVEEGKKVTAIKNVTANEEFFNGHFPEYPVMPGVLIVEALAQTSGIAMMQSEANKG
KIGLFAGIDGCRFKRQVVPGDQLLLEAEITRMRGAIAKAKVKATVEGDLVCEAEIMFALSDLPK

Sequences:

>Translated_144_residues
MLDIKKIKEILPHRYPFLLVDRVISVEEGKKVTAIKNVTANEEFFNGHFPEYPVMPGVLIVEALAQTSGIAMMQSEANKG
KIGLFAGIDGCRFKRQVVPGDQLLLEAEITRMRGAIAKAKVKATVEGDLVCEAEIMFALSDLPK
>Mature_144_residues
MLDIKKIKEILPHRYPFLLVDRVISVEEGKKVTAIKNVTANEEFFNGHFPEYPVMPGVLIVEALAQTSGIAMMQSEANKG
KIGLFAGIDGCRFKRQVVPGDQLLLEAEITRMRGAIAKAKVKATVEGDLVCEAEIMFALSDLPK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=141, Percent_Identity=51.7730496453901, Blast_Score=148, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 15858; Mature: 15858

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIKKIKEILPHRYPFLLVDRVISVEEGKKVTAIKNVTANEEFFNGHFPEYPVMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCCCCCCCHHHH
VEALAQTSGIAMMQSEANKGKIGLFAGIDGCRFKRQVVPGDQLLLEAEITRMRGAIAKAK
HHHHHHHCCEEEEECCCCCCCEEEEECCCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHE
VKATVEGDLVCEAEIMFALSDLPK
EEEEECCCEEEHHHHHHHHHCCCC
>Mature Secondary Structure
MLDIKKIKEILPHRYPFLLVDRVISVEEGKKVTAIKNVTANEEFFNGHFPEYPVMPGVLI
CCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCCCCCCCCCCHHHH
VEALAQTSGIAMMQSEANKGKIGLFAGIDGCRFKRQVVPGDQLLLEAEITRMRGAIAKAK
HHHHHHHCCEEEEECCCCCCCEEEEECCCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHE
VKATVEGDLVCEAEIMFALSDLPK
EEEEECCCEEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]