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The map label for this gene is ywcF [H]

Identifier: 226224974

GI number: 226224974

Start: 2467271

End: 2468446

Strand: Reverse

Name: ywcF [H]

Synonym: Lm4b_02395

Alternate gene names: 226224974

Gene position: 2468446-2467271 (Counterclockwise)

Preceding gene: 226224975

Following gene: 226224973

Centisome position: 84.75

GC content: 39.63

Gene sequence:

>1176_bases
ATGAATCAACAAAATAAACTAGCTGGACGCATTGATTACGGGATTGTCCTATCTATGATGTTACTCATGATAATCAGTTT
GGTGTCCATTTATAGTGCGCAATTAACAAATAATCAATATGATGCAAACTTTGTGGTCAAACAAGCCATGTGGTTTGTAG
TGTCGACATTTGCAATTATTGTCGTGATGCAACTAGATTATGATCGTCTGACGAAATGGGCTTACTACTTTTACGGACTA
GGTCTATTTTTACTCGTATTTGTATTGCTTTTTGGGAAAGAAGTAAAAGGAGCAAAGAGCTGGATTGTTATCCCGTTCTT
AGGGAACATTCAGCCATCTGAGGTTGTTAAGGTTATCTTAATTGTCGTTTTAGCAAAAGTGATTTGGGATCATAACCGAA
CTTATAAGGTCCACCGCTTTAGTTATGATGCTTGGTTACTTTTAAAGATTGGCTTATTTACATTAATGCCGCTTATTCTT
ATCATGCTGCAACCCGATTTAGGGACCGCGCTTGTATTTATCGCTATTATGTCGGGAATGATTCTTATTTCCGGAATTAC
ATGGAAAATTATCGTGCCACTTTTTGGCTCGATTGCGGCAATTGGGACGGCGCTTATTTGGATGGTTATTTATCACCAAA
ATTGGCTGACGAGTCTAGGCTTCAAACCCTATCAATTTGAGCGGATTACGACGTGGATTAATCCGGAGAATGATCCTCAA
GGCGGGGGTTATCAAGTGCTGCGAGCGATGACGGCAATTGGTTCTGGTCAGATTTCTGGGAACGGTGCGGGATATGATGC
CATTGCAATTCCAGAAAATCACAATGACTTTATTTTTACGATTGTAGCCGGAGATTATGGCTTTATTGGAGCTAGTATTT
TATTAGCAATTTATTTCTTATTAATTTATCAAATTATTCGTGTGGCGCTGGATGTTGGCGTACCGTTTTACTCTTACATT
TGTACGGGGGTTGTAATGATGTTAATGTTCCACGTACTGGAAAATGTTGGTATGAATATTGGTTTGCTGCCAATTACAGG
TATCCCGCTTCCGTTTATTAGTTACGGTGGTAGCGCCTTGCTCGGGAACATGATGGCTGTTGGCCTGGTGCTCGGGATAA
GGTTTAACTTTAAAAAATCGATGTTTGAAGTGAAAGAAGAAAATCACGCGTCTTAA

Upstream 100 bases:

>100_bases
CTTAGGGAAAGAAAATCGTTTCTGATTTTCTTTTTTAAACTGTTTGGGAGAAAGCGTTCGTTTTGTTTATACAAACCAAC
CAGTAAGGAGTAATTAAATA

Downstream 100 bases:

>100_bases
AAAAGAAAATACAGAAGTCGAAAATGGCTTTTGTATTTTTAAAACCAAGAATGAATACGCTTTCAAATGCTCTGTTTTTT
TCTAAGTGTTGCCATTTGTA

Product: cell division protein RodA, FtsW family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNQQNKLAGRIDYGIVLSMMLLMIISLVSIYSAQLTNNQYDANFVVKQAMWFVVSTFAIIVVMQLDYDRLTKWAYYFYGL
GLFLLVFVLLFGKEVKGAKSWIVIPFLGNIQPSEVVKVILIVVLAKVIWDHNRTYKVHRFSYDAWLLLKIGLFTLMPLIL
IMLQPDLGTALVFIAIMSGMILISGITWKIIVPLFGSIAAIGTALIWMVIYHQNWLTSLGFKPYQFERITTWINPENDPQ
GGGYQVLRAMTAIGSGQISGNGAGYDAIAIPENHNDFIFTIVAGDYGFIGASILLAIYFLLIYQIIRVALDVGVPFYSYI
CTGVVMMLMFHVLENVGMNIGLLPITGIPLPFISYGGSALLGNMMAVGLVLGIRFNFKKSMFEVKEENHAS

Sequences:

>Translated_391_residues
MNQQNKLAGRIDYGIVLSMMLLMIISLVSIYSAQLTNNQYDANFVVKQAMWFVVSTFAIIVVMQLDYDRLTKWAYYFYGL
GLFLLVFVLLFGKEVKGAKSWIVIPFLGNIQPSEVVKVILIVVLAKVIWDHNRTYKVHRFSYDAWLLLKIGLFTLMPLIL
IMLQPDLGTALVFIAIMSGMILISGITWKIIVPLFGSIAAIGTALIWMVIYHQNWLTSLGFKPYQFERITTWINPENDPQ
GGGYQVLRAMTAIGSGQISGNGAGYDAIAIPENHNDFIFTIVAGDYGFIGASILLAIYFLLIYQIIRVALDVGVPFYSYI
CTGVVMMLMFHVLENVGMNIGLLPITGIPLPFISYGGSALLGNMMAVGLVLGIRFNFKKSMFEVKEENHAS
>Mature_391_residues
MNQQNKLAGRIDYGIVLSMMLLMIISLVSIYSAQLTNNQYDANFVVKQAMWFVVSTFAIIVVMQLDYDRLTKWAYYFYGL
GLFLLVFVLLFGKEVKGAKSWIVIPFLGNIQPSEVVKVILIVVLAKVIWDHNRTYKVHRFSYDAWLLLKIGLFTLMPLIL
IMLQPDLGTALVFIAIMSGMILISGITWKIIVPLFGSIAAIGTALIWMVIYHQNWLTSLGFKPYQFERITTWINPENDPQ
GGGYQVLRAMTAIGSGQISGNGAGYDAIAIPENHNDFIFTIVAGDYGFIGASILLAIYFLLIYQIIRVALDVGVPFYSYI
CTGVVMMLMFHVLENVGMNIGLLPITGIPLPFISYGGSALLGNMMAVGLVLGIRFNFKKSMFEVKEENHAS

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=326, Percent_Identity=33.1288343558282, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786277, Length=371, Percent_Identity=26.9541778975741, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43682; Mature: 43682

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQNKLAGRIDYGIVLSMMLLMIISLVSIYSAQLTNNQYDANFVVKQAMWFVVSTFAII
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VVMQLDYDRLTKWAYYFYGLGLFLLVFVLLFGKEVKGAKSWIVIPFLGNIQPSEVVKVIL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHH
IVVLAKVIWDHNRTYKVHRFSYDAWLLLKIGLFTLMPLILIMLQPDLGTALVFIAIMSGM
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ILISGITWKIIVPLFGSIAAIGTALIWMVIYHQNWLTSLGFKPYQFERITTWINPENDPQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHEEEEECCCCCCC
GGGYQVLRAMTAIGSGQISGNGAGYDAIAIPENHNDFIFTIVAGDYGFIGASILLAIYFL
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LIYQIIRVALDVGVPFYSYICTGVVMMLMFHVLENVGMNIGLLPITGIPLPFISYGGSAL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCHHH
LGNMMAVGLVLGIRFNFKKSMFEVKEENHAS
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNQQNKLAGRIDYGIVLSMMLLMIISLVSIYSAQLTNNQYDANFVVKQAMWFVVSTFAII
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VVMQLDYDRLTKWAYYFYGLGLFLLVFVLLFGKEVKGAKSWIVIPFLGNIQPSEVVKVIL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHH
IVVLAKVIWDHNRTYKVHRFSYDAWLLLKIGLFTLMPLILIMLQPDLGTALVFIAIMSGM
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ILISGITWKIIVPLFGSIAAIGTALIWMVIYHQNWLTSLGFKPYQFERITTWINPENDPQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHEEEEECCCCCCC
GGGYQVLRAMTAIGSGQISGNGAGYDAIAIPENHNDFIFTIVAGDYGFIGASILLAIYFL
CCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LIYQIIRVALDVGVPFYSYICTGVVMMLMFHVLENVGMNIGLLPITGIPLPFISYGGSAL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCHHH
LGNMMAVGLVLGIRFNFKKSMFEVKEENHAS
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]