Click here to switch to the map view.

The map label for this gene is ywcF [H]

Identifier: 226224975

GI number: 226224975

Start: 2468522

End: 2469691

Strand: Reverse

Name: ywcF [H]

Synonym: Lm4b_02396

Alternate gene names: 226224975

Gene position: 2469691-2468522 (Counterclockwise)

Preceding gene: 226224976

Following gene: 226224974

Centisome position: 84.79

GC content: 36.75

Gene sequence:

>1170_bases
ATGGCCAGAAATAGAAAAAAGGCAGTTCGAATAGATTATTCGATTATATTTTTAATGATGTTGCTGTGTATTATTGGTCT
AGTAGCGATTTATGTCGCGGGGCTTGTTAACGACCAATATACAAATAATTTCTTATTGCAACAGTCTATTTGGATTGTTA
TTTCTACTGGGGTCGTTGTTGTTATTGTACTTTTTTTCGACTATGATAAGTTGCAATGGGCGGCGTATTATCTTTATGGG
ATAGGAAACTTATTGCTTGTACTCGTACTTATCGTTGGTGACGAGCGAAAAGGATCCAAGAGCTGGATTAGTATCGGATC
GCTTGGGAGCTTGCAACCATCGGAATTAATGAAAAGTTTTTTGATTTTAGCACTTGCAAAAGTCATTTGGGACCATAATA
AAAAATATAAATTACATACCGTGAGCTTAGATATGCAGTTACTGTTAAAAATAGGTATTGTTTCTATTCTTCCGCTTGGT
CTTGTAGCACTTCAACCAGACCTTGGGACGATTCTAGTATTTATTGCTATTATTATCGGTATGGTATTTATTAGTGGTGT
TACATGGAAAATTTTATTACCAGTTTTTAGTTCGATTGCGCTCATTGGTGGGACATTAATCTACTTAGTTATGTATAATC
AAGAGTTCTTACAAAAACTAGGATTTAAACCTTACCAATTTAAACGGATTACTTCTTGGTTAAGGCCGGAAGAGGATCCA
CTTGGTGACGGAATGCAGCTACTTCGGTCGATGCAAGCGATTGGTTCTGGGCAGTTACAAGGGAATGGAATCGGTAATCA
AGCCATTGCGATCCCGGAAAACCATAATGATTTTATTTTCTCCATTATTGGTGGGAATTTTGGTTTCATTGGTGGCTGTG
TACTTATTATGTTATACTTTTTACTGATTTACCAAATAATTCGAGTGGCATTAGATATTAATATTCCTTTTTATTCGTAT
ATTTGTACGGGTGTTTGCTCGATGATTTTGTTCCATGTTTTAGAAAATATCGGGATGACAATTGGTCTTCTTCCAATTAC
CGGTATTCCGCTACTTTTTGTCAGTTATGGGGGAAGCTCACTTCTTGGTGCATTTATGGCACTTGGGCTCGTGTTATCGG
CGAGATACAATGCTCCAGAAGTTAACTTAGGGAAAGAAAATCGTTTCTGA

Upstream 100 bases:

>100_bases
TATCCAAGGTAAACTTTATTATAATAGATGAAGGCTGTTGCTCTTTTTAAGAATAGCAGCTTTTTTACATTTAAATTCAA
ACACAAAAGGACGGAAAATA

Downstream 100 bases:

>100_bases
TTTTCTTTTTTAAACTGTTTGGGAGAAAGCGTTCGTTTTGTTTATACAAACCAACCAGTAAGGAGTAATTAAATAATGAA
TCAACAAAATAAACTAGCTG

Product: cell division protein RodA, FtsW family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MARNRKKAVRIDYSIIFLMMLLCIIGLVAIYVAGLVNDQYTNNFLLQQSIWIVISTGVVVVIVLFFDYDKLQWAAYYLYG
IGNLLLVLVLIVGDERKGSKSWISIGSLGSLQPSELMKSFLILALAKVIWDHNKKYKLHTVSLDMQLLLKIGIVSILPLG
LVALQPDLGTILVFIAIIIGMVFISGVTWKILLPVFSSIALIGGTLIYLVMYNQEFLQKLGFKPYQFKRITSWLRPEEDP
LGDGMQLLRSMQAIGSGQLQGNGIGNQAIAIPENHNDFIFSIIGGNFGFIGGCVLIMLYFLLIYQIIRVALDINIPFYSY
ICTGVCSMILFHVLENIGMTIGLLPITGIPLLFVSYGGSSLLGAFMALGLVLSARYNAPEVNLGKENRF

Sequences:

>Translated_389_residues
MARNRKKAVRIDYSIIFLMMLLCIIGLVAIYVAGLVNDQYTNNFLLQQSIWIVISTGVVVVIVLFFDYDKLQWAAYYLYG
IGNLLLVLVLIVGDERKGSKSWISIGSLGSLQPSELMKSFLILALAKVIWDHNKKYKLHTVSLDMQLLLKIGIVSILPLG
LVALQPDLGTILVFIAIIIGMVFISGVTWKILLPVFSSIALIGGTLIYLVMYNQEFLQKLGFKPYQFKRITSWLRPEEDP
LGDGMQLLRSMQAIGSGQLQGNGIGNQAIAIPENHNDFIFSIIGGNFGFIGGCVLIMLYFLLIYQIIRVALDINIPFYSY
ICTGVCSMILFHVLENIGMTIGLLPITGIPLLFVSYGGSSLLGAFMALGLVLSARYNAPEVNLGKENRF
>Mature_388_residues
ARNRKKAVRIDYSIIFLMMLLCIIGLVAIYVAGLVNDQYTNNFLLQQSIWIVISTGVVVVIVLFFDYDKLQWAAYYLYGI
GNLLLVLVLIVGDERKGSKSWISIGSLGSLQPSELMKSFLILALAKVIWDHNKKYKLHTVSLDMQLLLKIGIVSILPLGL
VALQPDLGTILVFIAIIIGMVFISGVTWKILLPVFSSIALIGGTLIYLVMYNQEFLQKLGFKPYQFKRITSWLRPEEDPL
GDGMQLLRSMQAIGSGQLQGNGIGNQAIAIPENHNDFIFSIIGGNFGFIGGCVLIMLYFLLIYQIIRVALDINIPFYSYI
CTGVCSMILFHVLENIGMTIGLLPITGIPLLFVSYGGSSLLGAFMALGLVLSARYNAPEVNLGKENRF

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=390, Percent_Identity=30.2564102564103, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786853, Length=326, Percent_Identity=32.5153374233129, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43120; Mature: 42989

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNRKKAVRIDYSIIFLMMLLCIIGLVAIYVAGLVNDQYTNNFLLQQSIWIVISTGVVV
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHEEEEEHHHHHH
VIVLFFDYDKLQWAAYYLYGIGNLLLVLVLIVGDERKGSKSWISIGSLGSLQPSELMKSF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHH
LILALAKVIWDHNKKYKLHTVSLDMQLLLKIGIVSILPLGLVALQPDLGTILVFIAIIIG
HHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MVFISGVTWKILLPVFSSIALIGGTLIYLVMYNQEFLQKLGFKPYQFKRITSWLRPEEDP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHCCCCCC
LGDGMQLLRSMQAIGSGQLQGNGIGNQAIAIPENHNDFIFSIIGGNFGFIGGCVLIMLYF
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHH
LLIYQIIRVALDINIPFYSYICTGVCSMILFHVLENIGMTIGLLPITGIPLLFVSYGGSS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCHHHEEECCCHH
LLGAFMALGLVLSARYNAPEVNLGKENRF
HHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARNRKKAVRIDYSIIFLMMLLCIIGLVAIYVAGLVNDQYTNNFLLQQSIWIVISTGVVV
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHEEEEEHHHHHH
VIVLFFDYDKLQWAAYYLYGIGNLLLVLVLIVGDERKGSKSWISIGSLGSLQPSELMKSF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHH
LILALAKVIWDHNKKYKLHTVSLDMQLLLKIGIVSILPLGLVALQPDLGTILVFIAIIIG
HHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
MVFISGVTWKILLPVFSSIALIGGTLIYLVMYNQEFLQKLGFKPYQFKRITSWLRPEEDP
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHCCCCCC
LGDGMQLLRSMQAIGSGQLQGNGIGNQAIAIPENHNDFIFSIIGGNFGFIGGCVLIMLYF
CCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHH
LLIYQIIRVALDINIPFYSYICTGVCSMILFHVLENIGMTIGLLPITGIPLLFVSYGGSS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCHHHEEECCCHH
LLGAFMALGLVLSARYNAPEVNLGKENRF
HHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]