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The map label for this gene is metQ [H]

Identifier: 226224965

GI number: 226224965

Start: 2459833

End: 2460663

Strand: Reverse

Name: metQ [H]

Synonym: Lm4b_02386

Alternate gene names: 226224965

Gene position: 2460663-2459833 (Counterclockwise)

Preceding gene: 226224966

Following gene: 226224963

Centisome position: 84.48

GC content: 35.74

Gene sequence:

>831_bases
ATGAAAAAGGTTCTTGGTTTCATTTTCACATTAAGTTTAGTTTTAGTACTTACAGCTTGCGGTGGCTCCTCAGATAAAGC
TTCATCTAGTAAAGACGATAACCAATTGGTAGTGGGTGCGTCCAATACACCACATGCCCAAATCTTAGAACAAGCAAAAC
CAATCTTGAAAGATAAAGGGATTGACTTGAAAATTGTTAAATATACAGATTACGTTATGCCTAATAAAGCGCTAGAAGAA
GGCGATTTAGATGCTAACTACTTCCAACATAAACCATATCTTGAACTAGAAGAAAAAGAAAAAGGCTACAAATTTGCTGA
TGTTGGCGCGATTCACATCGAACCAATGGGTATCTACTCTAAAAAAGTTAAAGACATTAAAGATCTAAAAGACGGCGCGC
AAGTTTTACTTTCTAACTCAAAATCTGATTGGCCGCGTGTTATTGGTATTTTTGTGGATAACGGACTATTAACGCTGAAA
GATGGCGTGAAACCACAAGATGCAACTTTTGATGATATTAAAGACAATCCGAAAAACTTGAAATTCAAATACGATTTTGA
TCCAGCTTACTTGATGACTGCCTACAATAACGAAGAAGGCGACGTTGTAGCGATTAACTCTAACTTTGTTGTAGATCAAG
GCTTAAACCCTTCTAAAGACGCTATTGCAATCGAAAGTAAAGACTCTCCTTATGCGAATATCGTTGTAACAACAGAAAAG
AAAAAAGATGATAAAAACATTAAAGAGCTAGTAAAAGTACTTCATTCAAAAGAAATTCAAGATTACATTACGAAAGAATG
GGACGGCGCTGTTGTTCCAGTGGATAAATAA

Upstream 100 bases:

>100_bases
GGCGACTTCTTAACAAAACGAACCGACAAACGCTAACCAATGTATATGAAGAAATTTATATAAAAAAACGCGGAATCCCC
GCAAAAAAGGAGAGAATTTC

Downstream 100 bases:

>100_bases
AATAGAAAAAATCCTTTTACCGTTTCGGTAAAAGGATTTTTTTATTGAGCGCTACTTAAATATAATTTCAGTCCATCGGA
AATGGCTTTATCTAATTCTT

Product: Conserved lipoprotein (ABC transporter binding protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MKKVLGFIFTLSLVLVLTACGGSSDKASSSKDDNQLVVGASNTPHAQILEQAKPILKDKGIDLKIVKYTDYVMPNKALEE
GDLDANYFQHKPYLELEEKEKGYKFADVGAIHIEPMGIYSKKVKDIKDLKDGAQVLLSNSKSDWPRVIGIFVDNGLLTLK
DGVKPQDATFDDIKDNPKNLKFKYDFDPAYLMTAYNNEEGDVVAINSNFVVDQGLNPSKDAIAIESKDSPYANIVVTTEK
KKDDKNIKELVKVLHSKEIQDYITKEWDGAVVPVDK

Sequences:

>Translated_276_residues
MKKVLGFIFTLSLVLVLTACGGSSDKASSSKDDNQLVVGASNTPHAQILEQAKPILKDKGIDLKIVKYTDYVMPNKALEE
GDLDANYFQHKPYLELEEKEKGYKFADVGAIHIEPMGIYSKKVKDIKDLKDGAQVLLSNSKSDWPRVIGIFVDNGLLTLK
DGVKPQDATFDDIKDNPKNLKFKYDFDPAYLMTAYNNEEGDVVAINSNFVVDQGLNPSKDAIAIESKDSPYANIVVTTEK
KKDDKNIKELVKVLHSKEIQDYITKEWDGAVVPVDK
>Mature_276_residues
MKKVLGFIFTLSLVLVLTACGGSSDKASSSKDDNQLVVGASNTPHAQILEQAKPILKDKGIDLKIVKYTDYVMPNKALEE
GDLDANYFQHKPYLELEEKEKGYKFADVGAIHIEPMGIYSKKVKDIKDLKDGAQVLLSNSKSDWPRVIGIFVDNGLLTLK
DGVKPQDATFDDIKDNPKNLKFKYDFDPAYLMTAYNNEEGDVVAINSNFVVDQGLNPSKDAIAIESKDSPYANIVVTTEK
KKDDKNIKELVKVLHSKEIQDYITKEWDGAVVPVDK

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable) [H]

COG id: COG1464

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface antigen

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpA lipoprotein family [H]

Homologues:

Organism=Escherichia coli, GI1786396, Length=259, Percent_Identity=38.2239382239382, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1790093, Length=246, Percent_Identity=35.3658536585366, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004872 [H]

Pfam domain/function: PF03180 Lipoprotein_9 [H]

EC number: NA

Molecular weight: Translated: 30718; Mature: 30718

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLGFIFTLSLVLVLTACGGSSDKASSSKDDNQLVVGASNTPHAQILEQAKPILKDKG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
IDLKIVKYTDYVMPNKALEEGDLDANYFQHKPYLELEEKEKGYKFADVGAIHIEPMGIYS
CCEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCEEEHHHCCCCEEECCCEEEEEECCHHH
KKVKDIKDLKDGAQVLLSNSKSDWPRVIGIFVDNGLLTLKDGVKPQDATFDDIKDNPKNL
HHHHHHHHHHHHHHHEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCHHCCCCCCCE
KFKYDFDPAYLMTAYNNEEGDVVAINSNFVVDQGLNPSKDAIAIESKDSPYANIVVTTEK
EEEECCCCEEEEEEEECCCCCEEEEECCEEEECCCCCCCCEEEEECCCCCEEEEEEEECC
KKDDKNIKELVKVLHSKEIQDYITKEWDGAVVPVDK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MKKVLGFIFTLSLVLVLTACGGSSDKASSSKDDNQLVVGASNTPHAQILEQAKPILKDKG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
IDLKIVKYTDYVMPNKALEEGDLDANYFQHKPYLELEEKEKGYKFADVGAIHIEPMGIYS
CCEEEEEEECCCCCCCCCCCCCCCCHHHCCCCCEEEHHHCCCCEEECCCEEEEEECCHHH
KKVKDIKDLKDGAQVLLSNSKSDWPRVIGIFVDNGLLTLKDGVKPQDATFDDIKDNPKNL
HHHHHHHHHHHHHHHEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCHHCCCCCCCE
KFKYDFDPAYLMTAYNNEEGDVVAINSNFVVDQGLNPSKDAIAIESKDSPYANIVVTTEK
EEEECCCCEEEEEEEECCCCCEEEEECCEEEECCCCCCCCEEEEECCCCCEEEEEEEECC
KKDDKNIKELVKVLHSKEIQDYITKEWDGAVVPVDK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]