| Definition | Listeria monocytogenes Clip81459, complete genome. |
|---|---|
| Accession | NC_012488 |
| Length | 2,912,690 |
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The map label for this gene is uvrA [H]
Identifier: 226224656
GI number: 226224656
Start: 2132047
End: 2134287
Strand: Direct
Name: uvrA [H]
Synonym: Lm4b_02071
Alternate gene names: 226224656
Gene position: 2132047-2134287 (Clockwise)
Preceding gene: 226224655
Following gene: 226224664
Centisome position: 73.2
GC content: 40.21
Gene sequence:
>2241_bases ATGGTACAAGAATATATTCGATTAAGAGGAGCGCGTGAAAACAATCTCCAAAATATTTCCCTAGATATCCCCAAACGAAA AATCACTATTTTTACTGGTGTATCTGGTTCCGGGAAATCTTCTATTGTATTTGAAACTATTGCCACGGAATCGCAAAGAC AGTTAAACGAAACATACAGCGCCTATCTTCGTAATTTCCTTCCGAAGTATACGCAGCCGGACGCAGATTCAATTGAAAAC CTCTCCACCTCTGTTATTATTGATCAAAAACGACTTGGCGGTAATTCCCGCTCCACCCTTGGTACCATCACGGATATTAA TTCGATTTTGCGATTACTTTTCTCGCGTGTCGGCAAGCCTAGTATCGGGACAGCAAATTTATTTTCTTTTAACGACCCTG CTGGTATGTGCCCTGATTGCCATGGTGTTGGACAAAAAGTTTCGGTTGATTTAGTCAAATTACTTGATCCAAATAAATCG CTCAAAGAAGGCGCCATCTTATTTCCGACGTTTTCGGTAGATTCATGGTACTGGAATTCCTATGCTTATTCCGGCTTTTT TGATGTGAATAAAAAAATAAAAGATTATACTGACGAAGAATACGATATGTTGTTACATGGGAAAGATATTAAAGTTTTCC TAGAAACACCCATGGGAAGCATGAACGCTACATATGAAGGGTTGATTCCAAAATTCAATCGTTTGTATATTCAAAAAGAA GGCGAAATGTCCGCCTCTACTAAAAAACGTGTCGATAAATTCACCCATATTGCGCCTTGTACAACTTGCGAAGGCACGAG ACTCTCCGCGCAAGCATTATCTTGTACAATAAATGGTGCAAATATCGCCGACTTCACAGCGATGCAATTAGATGAATTAA AAGCAACGATTGCGAGTATTGATGACCCTATCGCTGCTCCAATGGTCAAAAGTGTCACAGAGCGATTGCAACATTTGATT GATATTGGTCTTGGTTATATGACACTTGACCGCCAAACTGCTTCTCTTTCTGGTGGTGAATCACAACGCGTCAAAATGAT TCGTCATTTGAATAGTAGCTTAACTGACTTGCTTTATATTTTCGATGAACCAAGTATCGGTCTTCATCCACGAGATGTTC ATCGACTCAATGAATTACTCGTGAAATTGCGCGACAAAGGAAATACGATTCTCGTGGTGGAACATGACCCAGATGTGATC AAAATTGCCGACCATATTGTCGATGTCGGTCCGCACGCAGGAAAACATGGCGGTGAGATTCAGTTTGTCGGAAGTTACAC CGATTTGCTGAAATCAGACACACTAACTGGCAAGTTCCTCAATCGCCATTTACCAATTAATAGCAAACCGAGACAACCAA AAGGCTTTTTAACAACTGAAAAAAGTAGTCGCTTTAACCTAAAAGATATTCAGGCCAACATTCCAAAAGAAATTCTTACT GTAGTAACTGGCGTGGCTGGTTCGGGTAAGAGTACCTTGATTCATTCTGTTTTCCTAAAAGAATATCCAGATGCGATAGT GATCGACCAATCAGCCGCTCATGCCAATATTCGCTCTAATCCTGCCACCTATACTGGGATAATGGACCCGATTCGAAAAG CATTTGGAAAAGAAAATGATGTCAGTCCATCACTCTTTAGTTACAATTCCAAAGGCGCCTGCGAAAACTGTAAAGGACTT GGTTTCACAACTATGGATTTAGCTTTTATGGATTCGATTCGCACACCTTGCGAAGTATGTCACGGCAAGCGATTCCAAGA TTCTGTTTTGCAATATAAGCTAAATGGTAAATCCATTAGCGATGTGTTAGAACTAACTGTCTCAGAAGCACTCGATTTCT TTACGGATAAAAAAATCTTGAAGAAAATTGAGGCAATGGAAGAGGTTGGAATTGGTTATGTCACGCTTGGCCAAGCACTT AGCACCTTATCAGGCGGTGAGTGCCAACGTTTAAAACTCGCCAATGAGCTTCATAAAAAAGGGTCGATTTATATTATGGA TGAACCAACAACTGGTCTACACATGTCAGACATCGAACATATTTTGACGATTATCCACTCACTTGTAAATAAAGGAAATA CCGTTATTGTAATTGAACATAATGTCGATATTATTCGTAACGCAGACTGGATTATCGACCTTGGCCCAGAAGGCGGAAGT GCTGGCGGACAAATTATCTTCGAAGGCGCTCCCCTTGATTTACTTGAAAATAAACAATCATTAACTGCCAAATATCTTTA A
Upstream 100 bases:
>100_bases ACCAATTTTAACCTTGTAATCTTTACAAGGTTTTTGGTTGACTTTTATGGGGCTATTTTGCTAAGATGTTTGTCCGACTC AAAAAACAGGAGGTATGTGT
Downstream 100 bases:
>100_bases TGAAAAAAGCCGTTTTGTCTATAGCAGACAAAATGGCTTTTTTTATTGTAGTTTTTCTAAATAATCCACAGCATCTTGGA AAGTTTTAACTGGAACGATT
Product: excinuclease ABC (subunit A)
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 746; Mature: 746
Protein sequence:
>746_residues MVQEYIRLRGARENNLQNISLDIPKRKITIFTGVSGSGKSSIVFETIATESQRQLNETYSAYLRNFLPKYTQPDADSIEN LSTSVIIDQKRLGGNSRSTLGTITDINSILRLLFSRVGKPSIGTANLFSFNDPAGMCPDCHGVGQKVSVDLVKLLDPNKS LKEGAILFPTFSVDSWYWNSYAYSGFFDVNKKIKDYTDEEYDMLLHGKDIKVFLETPMGSMNATYEGLIPKFNRLYIQKE GEMSASTKKRVDKFTHIAPCTTCEGTRLSAQALSCTINGANIADFTAMQLDELKATIASIDDPIAAPMVKSVTERLQHLI DIGLGYMTLDRQTASLSGGESQRVKMIRHLNSSLTDLLYIFDEPSIGLHPRDVHRLNELLVKLRDKGNTILVVEHDPDVI KIADHIVDVGPHAGKHGGEIQFVGSYTDLLKSDTLTGKFLNRHLPINSKPRQPKGFLTTEKSSRFNLKDIQANIPKEILT VVTGVAGSGKSTLIHSVFLKEYPDAIVIDQSAAHANIRSNPATYTGIMDPIRKAFGKENDVSPSLFSYNSKGACENCKGL GFTTMDLAFMDSIRTPCEVCHGKRFQDSVLQYKLNGKSISDVLELTVSEALDFFTDKKILKKIEAMEEVGIGYVTLGQAL STLSGGECQRLKLANELHKKGSIYIMDEPTTGLHMSDIEHILTIIHSLVNKGNTVIVIEHNVDIIRNADWIIDLGPEGGS AGGQIIFEGAPLDLLENKQSLTAKYL
Sequences:
>Translated_746_residues MVQEYIRLRGARENNLQNISLDIPKRKITIFTGVSGSGKSSIVFETIATESQRQLNETYSAYLRNFLPKYTQPDADSIEN LSTSVIIDQKRLGGNSRSTLGTITDINSILRLLFSRVGKPSIGTANLFSFNDPAGMCPDCHGVGQKVSVDLVKLLDPNKS LKEGAILFPTFSVDSWYWNSYAYSGFFDVNKKIKDYTDEEYDMLLHGKDIKVFLETPMGSMNATYEGLIPKFNRLYIQKE GEMSASTKKRVDKFTHIAPCTTCEGTRLSAQALSCTINGANIADFTAMQLDELKATIASIDDPIAAPMVKSVTERLQHLI DIGLGYMTLDRQTASLSGGESQRVKMIRHLNSSLTDLLYIFDEPSIGLHPRDVHRLNELLVKLRDKGNTILVVEHDPDVI KIADHIVDVGPHAGKHGGEIQFVGSYTDLLKSDTLTGKFLNRHLPINSKPRQPKGFLTTEKSSRFNLKDIQANIPKEILT VVTGVAGSGKSTLIHSVFLKEYPDAIVIDQSAAHANIRSNPATYTGIMDPIRKAFGKENDVSPSLFSYNSKGACENCKGL GFTTMDLAFMDSIRTPCEVCHGKRFQDSVLQYKLNGKSISDVLELTVSEALDFFTDKKILKKIEAMEEVGIGYVTLGQAL STLSGGECQRLKLANELHKKGSIYIMDEPTTGLHMSDIEHILTIIHSLVNKGNTVIVIEHNVDIIRNADWIIDLGPEGGS AGGQIIFEGAPLDLLENKQSLTAKYL >Mature_746_residues MVQEYIRLRGARENNLQNISLDIPKRKITIFTGVSGSGKSSIVFETIATESQRQLNETYSAYLRNFLPKYTQPDADSIEN LSTSVIIDQKRLGGNSRSTLGTITDINSILRLLFSRVGKPSIGTANLFSFNDPAGMCPDCHGVGQKVSVDLVKLLDPNKS LKEGAILFPTFSVDSWYWNSYAYSGFFDVNKKIKDYTDEEYDMLLHGKDIKVFLETPMGSMNATYEGLIPKFNRLYIQKE GEMSASTKKRVDKFTHIAPCTTCEGTRLSAQALSCTINGANIADFTAMQLDELKATIASIDDPIAAPMVKSVTERLQHLI DIGLGYMTLDRQTASLSGGESQRVKMIRHLNSSLTDLLYIFDEPSIGLHPRDVHRLNELLVKLRDKGNTILVVEHDPDVI KIADHIVDVGPHAGKHGGEIQFVGSYTDLLKSDTLTGKFLNRHLPINSKPRQPKGFLTTEKSSRFNLKDIQANIPKEILT VVTGVAGSGKSTLIHSVFLKEYPDAIVIDQSAAHANIRSNPATYTGIMDPIRKAFGKENDVSPSLFSYNSKGACENCKGL GFTTMDLAFMDSIRTPCEVCHGKRFQDSVLQYKLNGKSISDVLELTVSEALDFFTDKKILKKIEAMEEVGIGYVTLGQAL STLSGGECQRLKLANELHKKGSIYIMDEPTTGLHMSDIEHILTIIHSLVNKGNTVIVIEHNVDIIRNADWIIDLGPEGGS AGGQIIFEGAPLDLLENKQSLTAKYL
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=677, Percent_Identity=37.370753323486, Blast_Score=430, Evalue=1e-121,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 82337; Mature: 82337
Theoretical pI: Translated: 6.76; Mature: 6.76
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVQEYIRLRGARENNLQNISLDIPKRKITIFTGVSGSGKSSIVFETIATESQRQLNETYS CCCHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCEEEEEHHCHHHHHHHHHHH AYLRNFLPKYTQPDADSIENLSTSVIIDQKRLGGNSRSTLGTITDINSILRLLFSRVGKP HHHHHHCCCCCCCCHHHHHCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC SIGTANLFSFNDPAGMCPDCHGVGQKVSVDLVKLLDPNKSLKEGAILFPTFSVDSWYWNS CCCCCEEEECCCCCCCCCCCCCCCCCHHEHHHHHCCCCCCHHCCEEEEEEECCCCEEECC YAYSGFFDVNKKIKDYTDEEYDMLLHGKDIKVFLETPMGSMNATYEGLIPKFNRLYIQKE EEECCEEECCCHHHCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHCCCCCEEEEEEEC GEMSASTKKRVDKFTHIAPCTTCEGTRLSAQALSCTINGANIADFTAMQLDELKATIASI CCCCHHHHHHHHHHHCCCCCCCCCCCCEECEEEEEEECCCCCCHHHHHHHHHHHHHHHHC DDPIAAPMVKSVTERLQHLIDIGLGYMTLDRQTASLSGGESQRVKMIRHLNSSLTDLLYI CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEE FDEPSIGLHPRDVHRLNELLVKLRDKGNTILVVEHDPDVIKIADHIVDVGPHAGKHGGEI ECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHCCCCCCCCCCEE QFVGSYTDLLKSDTLTGKFLNRHLPINSKPRQPKGFLTTEKSSRFNLKDIQANIPKEILT EEEECHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHCCHHHHHH VVTGVAGSGKSTLIHSVFLKEYPDAIVIDQSAAHANIRSNPATYTGIMDPIRKAFGKEND HHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC VSPSLFSYNSKGACENCKGLGFTTMDLAFMDSIRTPCEVCHGKRFQDSVLQYKLNGKSIS CCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHCCHHEEEECCCCHH DVLELTVSEALDFFTDKKILKKIEAMEEVGIGYVTLGQALSTLSGGECQRLKLANELHKK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHC GSIYIMDEPTTGLHMSDIEHILTIIHSLVNKGNTVIVIEHNVDIIRNADWIIDLGPEGGS CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCEEEEECCCCCC AGGQIIFEGAPLDLLENKQSLTAKYL CCCEEEECCCCHHHHCCCHHHHCCCC >Mature Secondary Structure MVQEYIRLRGARENNLQNISLDIPKRKITIFTGVSGSGKSSIVFETIATESQRQLNETYS CCCHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCEEEEEHHCHHHHHHHHHHH AYLRNFLPKYTQPDADSIENLSTSVIIDQKRLGGNSRSTLGTITDINSILRLLFSRVGKP HHHHHHCCCCCCCCHHHHHCCCCEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCC SIGTANLFSFNDPAGMCPDCHGVGQKVSVDLVKLLDPNKSLKEGAILFPTFSVDSWYWNS CCCCCEEEECCCCCCCCCCCCCCCCCHHEHHHHHCCCCCCHHCCEEEEEEECCCCEEECC YAYSGFFDVNKKIKDYTDEEYDMLLHGKDIKVFLETPMGSMNATYEGLIPKFNRLYIQKE EEECCEEECCCHHHCCCCCCCEEEEECCCEEEEEECCCCCCCCCHHHCCCCCEEEEEEEC GEMSASTKKRVDKFTHIAPCTTCEGTRLSAQALSCTINGANIADFTAMQLDELKATIASI CCCCHHHHHHHHHHHCCCCCCCCCCCCEECEEEEEEECCCCCCHHHHHHHHHHHHHHHHC DDPIAAPMVKSVTERLQHLIDIGLGYMTLDRQTASLSGGESQRVKMIRHLNSSLTDLLYI CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEE FDEPSIGLHPRDVHRLNELLVKLRDKGNTILVVEHDPDVIKIADHIVDVGPHAGKHGGEI ECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHHCCCCCCCCCCEE QFVGSYTDLLKSDTLTGKFLNRHLPINSKPRQPKGFLTTEKSSRFNLKDIQANIPKEILT EEEECHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHCCHHHHHH VVTGVAGSGKSTLIHSVFLKEYPDAIVIDQSAAHANIRSNPATYTGIMDPIRKAFGKEND HHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC VSPSLFSYNSKGACENCKGLGFTTMDLAFMDSIRTPCEVCHGKRFQDSVLQYKLNGKSIS CCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCHHCCHHEEEECCCCHH DVLELTVSEALDFFTDKKILKKIEAMEEVGIGYVTLGQALSTLSGGECQRLKLANELHKK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHC GSIYIMDEPTTGLHMSDIEHILTIIHSLVNKGNTVIVIEHNVDIIRNADWIIDLGPEGGS CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCEEEEECCCCCC AGGQIIFEGAPLDLLENKQSLTAKYL CCCEEEECCCCHHHHCCCHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8675016 [H]