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The map label for this gene is ctaA

Identifier: 226224664

GI number: 226224664

Start: 2139681

End: 2140598

Strand: Direct

Name: ctaA

Synonym: Lm4b_02079

Alternate gene names: 226224664

Gene position: 2139681-2140598 (Clockwise)

Preceding gene: 226224656

Following gene: 226224665

Centisome position: 73.46

GC content: 40.85

Gene sequence:

>918_bases
ATGAAAAAATTCTTGAAAGTTTGGTCCGTACTAACGATTATTTGTATGACGGTCGTTGTGTTTGGCGGAGCGCTCGTAAC
GAAAACTGGTTCAGCTGATGGCTGCGGTAATAGTTGGCCTCTATGTAATGGGCAGTTAGTTCGTTTAACAGATGTTACTC
CGGAAAAATTAATTGAATTCATGCACCGAATGACGACGGGAATCAGTTCGATTTTTGTTATTGTTTTAGCAATTTGTGCT
TGGATTTATATGAAAAATCGTCGCGAAACAAAACCACTTGCGATTATTGCGGTTCTGTTTCTAATTATTCAAGCGTTAAT
GGGAATGGCGGCTGTTGTTTGGGGACAAAATCCGTACATCATGGCGCTACACTTTGGAATTTCGATCATTTGTTATGCTT
CGATTGTATTGCTTGCCTTGATGATTTTTGAGGTAGACCGGAAATTCGATGCCAGAAACCTCGTGATGGGGACGAAATTA
CGTATTAATATTTATGCACTAACGATTTACACGTACTTAGCCGTTTATACTGGTGCACTTGTACGCCACGAAAAAGCAAG
TATGGCCGTTCCGGTTTGGCCTTTTGAAAATGGGCACTTTATTATGCCTACTTCAGTACAAGATTATGTGCAGTATTTCC
ACCGGTTAGCCGCATTTATTTTAATTGTTTGGTTGCTGTATGTAACTTGGCTTGTGTTCCGGGATTACAGAAGGTACCGC
GTGCTTACTTTTAGCATGGTGTTGTCGCTTGTGTTTATTGCACTTCAAGCCGTTACTGGGGCGCTGTCTGTTTATACAGG
AGTGAACTTGTATATCGCGCTTGCCCATAGCTTGATTATTACGATGTTGTTCGCGCTACTTTGCTACTTATGCTTACTGG
CATCAAGAAGTAAAAGCAATCGACTACGAATAAAATAA

Upstream 100 bases:

>100_bases
TAAACACGCTACAATTAGTTTGATGTGTACTCATGAACTTATACATAGACACAAATTTTAGTAAAATCTCACACGCATCT
AAAGGAGAGATTGGTAGATA

Downstream 100 bases:

>100_bases
CGAACACGGCTGGCAACTTTTTGTTGTCAGCTTTTTTATTTGTTTACGGCTTTTGCGTCGTTTTATGCTAAAATAAGTGA
GAGTATAAGTCAAACGAGGT

Product: heme O oxygenase

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKKFLKVWSVLTIICMTVVVFGGALVTKTGSADGCGNSWPLCNGQLVRLTDVTPEKLIEFMHRMTTGISSIFVIVLAICA
WIYMKNRRETKPLAIIAVLFLIIQALMGMAAVVWGQNPYIMALHFGISIICYASIVLLALMIFEVDRKFDARNLVMGTKL
RINIYALTIYTYLAVYTGALVRHEKASMAVPVWPFENGHFIMPTSVQDYVQYFHRLAAFILIVWLLYVTWLVFRDYRRYR
VLTFSMVLSLVFIALQAVTGALSVYTGVNLYIALAHSLIITMLFALLCYLCLLASRSKSNRLRIK

Sequences:

>Translated_305_residues
MKKFLKVWSVLTIICMTVVVFGGALVTKTGSADGCGNSWPLCNGQLVRLTDVTPEKLIEFMHRMTTGISSIFVIVLAICA
WIYMKNRRETKPLAIIAVLFLIIQALMGMAAVVWGQNPYIMALHFGISIICYASIVLLALMIFEVDRKFDARNLVMGTKL
RINIYALTIYTYLAVYTGALVRHEKASMAVPVWPFENGHFIMPTSVQDYVQYFHRLAAFILIVWLLYVTWLVFRDYRRYR
VLTFSMVLSLVFIALQAVTGALSVYTGVNLYIALAHSLIITMLFALLCYLCLLASRSKSNRLRIK
>Mature_305_residues
MKKFLKVWSVLTIICMTVVVFGGALVTKTGSADGCGNSWPLCNGQLVRLTDVTPEKLIEFMHRMTTGISSIFVIVLAICA
WIYMKNRRETKPLAIIAVLFLIIQALMGMAAVVWGQNPYIMALHFGISIICYASIVLLALMIFEVDRKFDARNLVMGTKL
RINIYALTIYTYLAVYTGALVRHEKASMAVPVWPFENGHFIMPTSVQDYVQYFHRLAAFILIVWLLYVTWLVFRDYRRYR
VLTFSMVLSLVFIALQAVTGALSVYTGVNLYIALAHSLIITMLFALLCYLCLLASRSKSNRLRIK

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_LISIN (Q929V9)

Other databases:

- EMBL:   AL596171
- PIR:   AB1703
- RefSeq:   NP_471498.1
- GeneID:   1130895
- GenomeReviews:   AL592022_GR
- KEGG:   lin:lin2164
- GenoList:   LIN2164
- HOGENOM:   HBG313632
- OMA:   MGHRVAA
- ProtClustDB:   CLSK2753228
- BioCyc:   LINN272626:LIN2164-MONOMER
- HAMAP:   MF_01664
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 34567; Mature: 34567

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: BINDING 276-276

Signals:

None

Transmembrane regions:

HASH(0x1f37d66c)-; HASH(0x20070258)-; HASH(0x208973ac)-; HASH(0x20873220)-; HASH(0x20898b04)-; HASH(0x20683764)-; HASH(0x207b3250)-; HASH(0x205ca0f4)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLKVWSVLTIICMTVVVFGGALVTKTGSADGCGNSWPLCNGQLVRLTDVTPEKLIEF
CHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHH
MHRMTTGISSIFVIVLAICAWIYMKNRRETKPLAIIAVLFLIIQALMGMAAVVWGQNPYI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
MALHFGISIICYASIVLLALMIFEVDRKFDARNLVMGTKLRINIYALTIYTYLAVYTGAL
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEHHHHHHHHHHHHHHHH
VRHEKASMAVPVWPFENGHFIMPTSVQDYVQYFHRLAAFILIVWLLYVTWLVFRDYRRYR
HHCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLTFSMVLSLVFIALQAVTGALSVYTGVNLYIALAHSLIITMLFALLCYLCLLASRSKSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RLRIK
CCCCH
>Mature Secondary Structure
MKKFLKVWSVLTIICMTVVVFGGALVTKTGSADGCGNSWPLCNGQLVRLTDVTPEKLIEF
CHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHH
MHRMTTGISSIFVIVLAICAWIYMKNRRETKPLAIIAVLFLIIQALMGMAAVVWGQNPYI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
MALHFGISIICYASIVLLALMIFEVDRKFDARNLVMGTKLRINIYALTIYTYLAVYTGAL
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEHHHHHHHHHHHHHHHH
VRHEKASMAVPVWPFENGHFIMPTSVQDYVQYFHRLAAFILIVWLLYVTWLVFRDYRRYR
HHCCCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLTFSMVLSLVFIALQAVTGALSVYTGVNLYIALAHSLIITMLFALLCYLCLLASRSKSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RLRIK
CCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11679669