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The map label for this gene is mreBH [H]

Identifier: 226224316

GI number: 226224316

Start: 1761399

End: 1762391

Strand: Direct

Name: mreBH [H]

Synonym: Lm4b_01727

Alternate gene names: 226224316

Gene position: 1761399-1762391 (Clockwise)

Preceding gene: 226224315

Following gene: 226224319

Centisome position: 60.47

GC content: 43.4

Gene sequence:

>993_bases
ATGTTTGGAACAACAACTATTGGAATTGATTTAGGTACTGCGAATATTTTAGTTTACAGTAAAGAAAAAGGCATTATACT
GAATGAACCTTCTGTGGTCGCGCTAAATGCGAATGATGGAACGGTACTTGCGATTGGCCAGGAAGCAAAAGAGATGATTG
GTAAAACGCCGACTTCGATTTCTGCTGTAAGACCAATGAAGGACGGTGTTATTGCTGATTTTGATTTAACGAGCGGACTT
TTGCGCGAGATTATGCGCCGGATTTCAGTTAGTGGTGTGAGAAAGCCCAATGTGGTCGTTTGTACCCCAACTGGTGCAAC
GTCAGTCGAGCGTCGCGCTATTTCAGACGCGGTAAGATCAACTGGTGCTCGTTCAGTCGTTTTAATTGAAGAACCTGTTG
CAGCTGCAATTGGTGCTGATTTACCTGTCGCTGAGCCTGTCGCTAACGTAATTGTAGATATTGGTGGCGGCACAAGTGAG
ATTGCGATTATTTCATACGGCGGTGTGGTTTCAAGCACTTCGATTCGCACAGGTGGCGATCATATGGATGAAGAAATCAT
TCAATACATCCGCAAAAATTACAACCTTTTAATCGGTCAAACAACAGCAGAACGAATTAAAATGGAGCTTGGTTATGCGC
CGATCGAACACGTAACACAAACTGCGGATATCCGTGGTCGCGATTTGCTTACTGGCTTACCAAAAACAATCCAAGTAAGC
TCTACGGAAATCCAAAGCGCTTTAGCTGAAACATTACAACGTATATTAGAAGCTATTCGGAATACGCTTGAACTTTGCCC
ACCAGAATTAAGTGGTGATATTGTCGATCGCGGCATTATTTTAAGTGGTGGTGGCTCCCTACTTCAAGGTTTCCGCGACT
GGCTTGTACAAGAAATAGATGTCCCTGTACATATGGCTCCAAGTCCTTTGGAATCCGTTGCAATTGGCACAGGTAGATCC
CTCGTTTTTGCAGATAAATTAGCTAAAAATTAA

Upstream 100 bases:

>100_bases
ATCCATGTTTAAATAATGCTTATATGGTGAAAAAAGTCTATACTGTTAGTTGTACACCTAGAATTTACTCGCTATTTTTA
ATAGAAAGTTAGGTGTGAGA

Downstream 100 bases:

>100_bases
TTGTAGTAAGCATCTGGTCGCATGGTAACCCTTGCAGCCAGATGCTTCTTTATCTTGCTGAAACCCCTTATTTCTGGTAA
ACTTATTTCTGGTGTCTGGC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MFGTTTIGIDLGTANILVYSKEKGIILNEPSVVALNANDGTVLAIGQEAKEMIGKTPTSISAVRPMKDGVIADFDLTSGL
LREIMRRISVSGVRKPNVVVCTPTGATSVERRAISDAVRSTGARSVVLIEEPVAAAIGADLPVAEPVANVIVDIGGGTSE
IAIISYGGVVSSTSIRTGGDHMDEEIIQYIRKNYNLLIGQTTAERIKMELGYAPIEHVTQTADIRGRDLLTGLPKTIQVS
STEIQSALAETLQRILEAIRNTLELCPPELSGDIVDRGIILSGGGSLLQGFRDWLVQEIDVPVHMAPSPLESVAIGTGRS
LVFADKLAKN

Sequences:

>Translated_330_residues
MFGTTTIGIDLGTANILVYSKEKGIILNEPSVVALNANDGTVLAIGQEAKEMIGKTPTSISAVRPMKDGVIADFDLTSGL
LREIMRRISVSGVRKPNVVVCTPTGATSVERRAISDAVRSTGARSVVLIEEPVAAAIGADLPVAEPVANVIVDIGGGTSE
IAIISYGGVVSSTSIRTGGDHMDEEIIQYIRKNYNLLIGQTTAERIKMELGYAPIEHVTQTADIRGRDLLTGLPKTIQVS
STEIQSALAETLQRILEAIRNTLELCPPELSGDIVDRGIILSGGGSLLQGFRDWLVQEIDVPVHMAPSPLESVAIGTGRS
LVFADKLAKN
>Mature_330_residues
MFGTTTIGIDLGTANILVYSKEKGIILNEPSVVALNANDGTVLAIGQEAKEMIGKTPTSISAVRPMKDGVIADFDLTSGL
LREIMRRISVSGVRKPNVVVCTPTGATSVERRAISDAVRSTGARSVVLIEEPVAAAIGADLPVAEPVANVIVDIGGGTSE
IAIISYGGVVSSTSIRTGGDHMDEEIIQYIRKNYNLLIGQTTAERIKMELGYAPIEHVTQTADIRGRDLLTGLPKTIQVS
STEIQSALAETLQRILEAIRNTLELCPPELSGDIVDRGIILSGGGSLLQGFRDWLVQEIDVPVHMAPSPLESVAIGTGRS
LVFADKLAKN

Specific function: Involved In Formation Of The Rod Shape Of The Cell. May Act As A Negative Regulator Of Ftsi. [C]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=331, Percent_Identity=49.5468277945619, Blast_Score=318, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 34921; Mature: 34921

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGTTTIGIDLGTANILVYSKEKGIILNEPSVVALNANDGTVLAIGQEAKEMIGKTPTSI
CCCCEEEEEEECCEEEEEEECCCCEEECCCCEEEEECCCCEEEEECHHHHHHHCCCCCCH
SAVRPMKDGVIADFDLTSGLLREIMRRISVSGVRKPNVVVCTPTGATSVERRAISDAVRS
HHCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHC
TGARSVVLIEEPVAAAIGADLPVAEPVANVIVDIGGGTSEIAIISYGGVVSSTSIRTGGD
CCCCEEEEEECCHHHHHCCCCCCHHHHHHEEEECCCCCCEEEEEEECCEEECCCCCCCCC
HMDEEIIQYIRKNYNLLIGQTTAERIKMELGYAPIEHVTQTADIRGRDLLTGLPKTIQVS
HHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHCCCCEEEEC
STEIQSALAETLQRILEAIRNTLELCPPELSGDIVDRGIILSGGGSLLQGFRDWLVQEID
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEEEECCHHHHHHHHHHHHHHCC
VPVHMAPSPLESVAIGTGRSLVFADKLAKN
CCEEECCCCHHHHEECCCCCEEEHHHHHCC
>Mature Secondary Structure
MFGTTTIGIDLGTANILVYSKEKGIILNEPSVVALNANDGTVLAIGQEAKEMIGKTPTSI
CCCCEEEEEEECCEEEEEEECCCCEEECCCCEEEEECCCCEEEEECHHHHHHHCCCCCCH
SAVRPMKDGVIADFDLTSGLLREIMRRISVSGVRKPNVVVCTPTGATSVERRAISDAVRS
HHCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHC
TGARSVVLIEEPVAAAIGADLPVAEPVANVIVDIGGGTSEIAIISYGGVVSSTSIRTGGD
CCCCEEEEEECCHHHHHCCCCCCHHHHHHEEEECCCCCCEEEEEEECCEEECCCCCCCCC
HMDEEIIQYIRKNYNLLIGQTTAERIKMELGYAPIEHVTQTADIRGRDLLTGLPKTIQVS
HHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHCCCCEEEEC
STEIQSALAETLQRILEAIRNTLELCPPELSGDIVDRGIILSGGGSLLQGFRDWLVQEID
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCEEEECCHHHHHHHHHHHHHHCC
VPVHMAPSPLESVAIGTGRSLVFADKLAKN
CCEEECCCCHHHHEECCCCCEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]