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The map label for this gene is fosX [H]

Identifier: 226224305

GI number: 226224305

Start: 1751903

End: 1752304

Strand: Reverse

Name: fosX [H]

Synonym: Lm4b_01716

Alternate gene names: 226224305

Gene position: 1752304-1751903 (Counterclockwise)

Preceding gene: 226224306

Following gene: 226224304

Centisome position: 60.16

GC content: 34.33

Gene sequence:

>402_bases
ATGATTTCAGGATTAAGCCATATCACTTTAATTGTGAAAGATTTGAATAAAACAACTGCTTTCTTACAGAATATTTTTAA
TGCAGAAGAAATCTATTCTAGTGGCGACAAAACATTTTCGCTTTCCAAAGAAAAATTTTTTCTAATAGCTGGTTTGTGGA
TTTGCATTATGGAAGGAGATTCTTTACAAGAGCGAACTTACAATCATATTGCTTTCCAAATTCAATCCGAGGAAGTGGAT
GAATATACTGAGCGGATTAAAGCTCTCGGTGTGGAAATGAAACCAGAACGTCCCAGAGTCCAAGGTGAAGGACGTTCCAT
TTATTTTTATGATTTTGATAATCATCTGTTTGAATTACACGCTGGTACATTAGAAGAACGCTTAAAAAGGTATCACGAAT
AG

Upstream 100 bases:

>100_bases
GCATTCGCTATATGCAACCCGTCGATATGTTCCCGCAAACAGCTCACGTGGAAACCGTAGTACTCTTGCAGTTAAAAGAT
AAATAAAGGACTGGTGGTAC

Downstream 100 bases:

>100_bases
AAATAACACCTAATAGGAGGAAACAAACATGAAAAAACTATTTGATGAAACGAATGAATTTGAAGCAAAGTACTACCGAA
CTATTTGGTACGGCTACATC

Product: glutathione transferase-fosfomycin resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MISGLSHITLIVKDLNKTTAFLQNIFNAEEIYSSGDKTFSLSKEKFFLIAGLWICIMEGDSLQERTYNHIAFQIQSEEVD
EYTERIKALGVEMKPERPRVQGEGRSIYFYDFDNHLFELHAGTLEERLKRYHE

Sequences:

>Translated_133_residues
MISGLSHITLIVKDLNKTTAFLQNIFNAEEIYSSGDKTFSLSKEKFFLIAGLWICIMEGDSLQERTYNHIAFQIQSEEVD
EYTERIKALGVEMKPERPRVQGEGRSIYFYDFDNHLFELHAGTLEERLKRYHE
>Mature_133_residues
MISGLSHITLIVKDLNKTTAFLQNIFNAEEIYSSGDKTFSLSKEKFFLIAGLWICIMEGDSLQERTYNHIAFQIQSEEVD
EYTERIKALGVEMKPERPRVQGEGRSIYFYDFDNHLFELHAGTLEERLKRYHE

Specific function: Catalyzes the hydration of fosfomycin [H]

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fosfomycin resistance protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 15571; Mature: 15571

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISGLSHITLIVKDLNKTTAFLQNIFNAEEIYSSGDKTFSLSKEKFFLIAGLWICIMEGD
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCHHHHHEEEEEEEECCC
SLQERTYNHIAFQIQSEEVDEYTERIKALGVEMKPERPRVQGEGRSIYFYDFDNHLFELH
CHHHHCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEC
AGTLEERLKRYHE
CCHHHHHHHHHCC
>Mature Secondary Structure
MISGLSHITLIVKDLNKTTAFLQNIFNAEEIYSSGDKTFSLSKEKFFLIAGLWICIMEGD
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEECCCHHHHHEEEEEEEECCC
SLQERTYNHIAFQIQSEEVDEYTERIKALGVEMKPERPRVQGEGRSIYFYDFDNHLFELH
CHHHHCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEC
AGTLEERLKRYHE
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]