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The map label for this gene is trpD

Identifier: 226224232

GI number: 226224232

Start: 1657078

End: 1658097

Strand: Reverse

Name: trpD

Synonym: Lm4b_01642

Alternate gene names: 226224232

Gene position: 1658097-1657078 (Counterclockwise)

Preceding gene: 226224233

Following gene: 226224231

Centisome position: 56.93

GC content: 40.88

Gene sequence:

>1020_bases
ATGGAAATCTTACTACAAAAAGTATATGACCAAGAAAATTTATCCAAAGAAGAAATGACAATGATCGCAACAGAAATTTT
TGAAGGACGACTTTCGAAAACGAAAATAGCTGCTTTTTTAATGGCGCTCAAAGTGAAAGGAGAAACGGCAGAAGAAATGG
CGGGAATCGCGCAGGCGATGCAACGAGTGGCTATTCAAGTGGCTTTTCCAGCCGGGACAGCGATGGATAATTGCGGAACA
GGTGGAGATAAATCCAATAGTTTTAATATTAGTACTACGTCGGCTTTTGTTCTTGCGGCTGCGGGGATTCCGGTTGCGAA
ACATGGGAATAGAAGTATTTCTAGTCGTTCAGGTAGTGCTGATGTTTGTCAGGAATTAGGGATTGATATTAATATGCGCC
CAGAAGATATGACTTATTTACTCGAAAAAGTCGGGATTGCCTTTTTGTTCGCGCCACATGTTCACCCGAATATGAAGTAC
GTTATGGATGTTCGAAAAGAACTTGGAACGCCAACGATATTTAATTTGATTGGCCCACTCACAAATCCGGTCCATTTAGA
AACGCAATTAATGGGAATTTATCGTCGTGATTTGTTAGAGCAAACAGCGGAAGTACTCGGCCAGCTCGGACGAAAACGCG
CAGTTGTTTTAAATGGCGCTGGTTTTATGGATGAAGCTTCTCTGGCTGGAGAAAATCATTATGCGTTATATGAAAATGGT
GAAGTTCACTTATATACACTGCGTCCGGAAGATGTTGGTTTAACTAGCTATCCTCTCGAAGCAATTACAGGCGGAGAAGC
TAAAGAAAATGCAGCAATTTTGCGTAGTGTGCTTGACGGAGAACCAGGAGCTTACTTAGATACAGTGCTTTTAAATGCCG
GATTTGGTTTATTTGCAAATGGCAAAGTGACAACGGTACAAGAAGGCGTGGATTTAGCAAGAGATTTAATTAGAAGTGGT
TTAGCCAAACAAAAATTGGCAGATTTAATTACTTATCAAAAAGAGGTGCTAGCAAAATGA

Upstream 100 bases:

>100_bases
CCGGTTTACGGTTTGCAATTTCATCCTGAATCAATTGGTACGAATGATGGAAAACAAATGATGGAAAACTTTATTCATAT
AGTGGAAGGAGCGCGAGAAA

Downstream 100 bases:

>100_bases
CATTTTTAGAAGAAATTTTAGCGCAAAAAGCAGTAGAAGTTGCAGACATGCCCTTAGAAAAAGTAGCCGAAAAACGGAAA
ACTTATTCGTTTTATGAATT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MEILLQKVYDQENLSKEEMTMIATEIFEGRLSKTKIAAFLMALKVKGETAEEMAGIAQAMQRVAIQVAFPAGTAMDNCGT
GGDKSNSFNISTTSAFVLAAAGIPVAKHGNRSISSRSGSADVCQELGIDINMRPEDMTYLLEKVGIAFLFAPHVHPNMKY
VMDVRKELGTPTIFNLIGPLTNPVHLETQLMGIYRRDLLEQTAEVLGQLGRKRAVVLNGAGFMDEASLAGENHYALYENG
EVHLYTLRPEDVGLTSYPLEAITGGEAKENAAILRSVLDGEPGAYLDTVLLNAGFGLFANGKVTTVQEGVDLARDLIRSG
LAKQKLADLITYQKEVLAK

Sequences:

>Translated_339_residues
MEILLQKVYDQENLSKEEMTMIATEIFEGRLSKTKIAAFLMALKVKGETAEEMAGIAQAMQRVAIQVAFPAGTAMDNCGT
GGDKSNSFNISTTSAFVLAAAGIPVAKHGNRSISSRSGSADVCQELGIDINMRPEDMTYLLEKVGIAFLFAPHVHPNMKY
VMDVRKELGTPTIFNLIGPLTNPVHLETQLMGIYRRDLLEQTAEVLGQLGRKRAVVLNGAGFMDEASLAGENHYALYENG
EVHLYTLRPEDVGLTSYPLEAITGGEAKENAAILRSVLDGEPGAYLDTVLLNAGFGLFANGKVTTVQEGVDLARDLIRSG
LAKQKLADLITYQKEVLAK
>Mature_339_residues
MEILLQKVYDQENLSKEEMTMIATEIFEGRLSKTKIAAFLMALKVKGETAEEMAGIAQAMQRVAIQVAFPAGTAMDNCGT
GGDKSNSFNISTTSAFVLAAAGIPVAKHGNRSISSRSGSADVCQELGIDINMRPEDMTYLLEKVGIAFLFAPHVHPNMKY
VMDVRKELGTPTIFNLIGPLTNPVHLETQLMGIYRRDLLEQTAEVLGQLGRKRAVVLNGAGFMDEASLAGENHYALYENG
EVHLYTLRPEDVGLTSYPLEAITGGEAKENAAILRSVLDGEPGAYLDTVLLNAGFGLFANGKVTTVQEGVDLARDLIRSG
LAKQKLADLITYQKEVLAK

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=281, Percent_Identity=41.9928825622776, Blast_Score=204, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=325, Percent_Identity=31.3846153846154, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36699; Mature: 36699

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILLQKVYDQENLSKEEMTMIATEIFEGRLSKTKIAAFLMALKVKGETAEEMAGIAQAM
CHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QRVAIQVAFPAGTAMDNCGTGGDKSNSFNISTTSAFVLAAAGIPVAKHGNRSISSRSGSA
HHHEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCEECCCCCCCCCCCCCH
DVCQELGIDINMRPEDMTYLLEKVGIAFLFAPHVHPNMKYVMDVRKELGTPTIFNLIGPL
HHHHHCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCC
TNPVHLETQLMGIYRRDLLEQTAEVLGQLGRKRAVVLNGAGFMDEASLAGENHYALYENG
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCEEEEECC
EVHLYTLRPEDVGLTSYPLEAITGGEAKENAAILRSVLDGEPGAYLDTVLLNAGFGLFAN
CEEEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEC
GKVTTVQEGVDLARDLIRSGLAKQKLADLITYQKEVLAK
CEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEILLQKVYDQENLSKEEMTMIATEIFEGRLSKTKIAAFLMALKVKGETAEEMAGIAQAM
CHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QRVAIQVAFPAGTAMDNCGTGGDKSNSFNISTTSAFVLAAAGIPVAKHGNRSISSRSGSA
HHHEEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCEECCCCCCCCCCCCCH
DVCQELGIDINMRPEDMTYLLEKVGIAFLFAPHVHPNMKYVMDVRKELGTPTIFNLIGPL
HHHHHCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCC
TNPVHLETQLMGIYRRDLLEQTAEVLGQLGRKRAVVLNGAGFMDEASLAGENHYALYENG
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCCCEEEEECC
EVHLYTLRPEDVGLTSYPLEAITGGEAKENAAILRSVLDGEPGAYLDTVLLNAGFGLFAN
CEEEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEC
GKVTTVQEGVDLARDLIRSGLAKQKLADLITYQKEVLAK
CEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]