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The map label for this gene is trpG

Identifier: 226224233

GI number: 226224233

Start: 1658069

End: 1658674

Strand: Reverse

Name: trpG

Synonym: Lm4b_01643

Alternate gene names: 226224233

Gene position: 1658674-1658069 (Counterclockwise)

Preceding gene: 226224234

Following gene: 226224232

Centisome position: 56.95

GC content: 38.94

Gene sequence:

>606_bases
ATGATTCTATTAATTGATAATTACGATTCTTTTACATTTAATTTAGAACAGTATTTAGCAGAATTTAGTGAAGTGGTTGT
GAAACGGAATGATGCGACTGATTTAATGGAAATGGCGGCTTTAGCTGATGGGATAGTTCTTTCACCGGGACCAGGAAAAC
CAAGTGATGCTGGTCTTTTAGAAGAAGTAGTTGCAAAATTTGCGAAAGAAAAGCCTTTGCTTGGAATTTGTTTAGGTCAT
CAGGCGATTGGTGAGGTATTCGGCGGAGACGTAAAAAGAGCGGCGAAAATCCGCCACGGGAAAGTTTCTACTATGCGGCA
AACCGCTGGAGCAATCTTTGCTAATTTACCGGAAGAAATGCCTGTGATGCGTTATCATTCTTTAATAGTAGATAAAAACA
CGTTGCCACAAGTTTTGGAAGTGTTAGCAGTAGCGACGGACGATGCGGAAGTGATGGCAATGAAAGTAAAAGATTATCCG
GTTTACGGTTTGCAATTTCATCCTGAATCAATTGGTACGAATGATGGAAAACAAATGATGGAAAACTTTATTCATATAGT
GGAAGGAGCGCGAGAAAATGGAAATCTTACTACAAAAAGTATATGA

Upstream 100 bases:

>100_bases
CTTATGTTCAAGCTGGTGCAGGAATTGTCTATGATTCCGATCCAGAAAGCGAATACTTAGAAACATTACAAAAAGCAAAG
GCACTTTTGGAGGTGGGAGA

Downstream 100 bases:

>100_bases
CCAAGAAAATTTATCCAAAGAAGAAATGACAATGATCGCAACAGAAATTTTTGAAGGACGACTTTCGAAAACGAAAATAG
CTGCTTTTTTAATGGCGCTC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MILLIDNYDSFTFNLEQYLAEFSEVVVKRNDATDLMEMAALADGIVLSPGPGKPSDAGLLEEVVAKFAKEKPLLGICLGH
QAIGEVFGGDVKRAAKIRHGKVSTMRQTAGAIFANLPEEMPVMRYHSLIVDKNTLPQVLEVLAVATDDAEVMAMKVKDYP
VYGLQFHPESIGTNDGKQMMENFIHIVEGARENGNLTTKSI

Sequences:

>Translated_201_residues
MILLIDNYDSFTFNLEQYLAEFSEVVVKRNDATDLMEMAALADGIVLSPGPGKPSDAGLLEEVVAKFAKEKPLLGICLGH
QAIGEVFGGDVKRAAKIRHGKVSTMRQTAGAIFANLPEEMPVMRYHSLIVDKNTLPQVLEVLAVATDDAEVMAMKVKDYP
VYGLQFHPESIGTNDGKQMMENFIHIVEGARENGNLTTKSI
>Mature_201_residues
MILLIDNYDSFTFNLEQYLAEFSEVVVKRNDATDLMEMAALADGIVLSPGPGKPSDAGLLEEVVAKFAKEKPLLGICLGH
QAIGEVFGGDVKRAAKIRHGKVSTMRQTAGAIFANLPEEMPVMRYHSLIVDKNTLPQVLEVLAVATDDAEVMAMKVKDYP
VYGLQFHPESIGTNDGKQMMENFIHIVEGARENGNLTTKSI

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=46.524064171123, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1787517, Length=199, Percent_Identity=41.2060301507538, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1786215, Length=170, Percent_Identity=28.8235294117647, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322638, Length=194, Percent_Identity=43.298969072165, Blast_Score=164, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21995; Mature: 21995

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTFNLEQYLAEFSEVVVKRNDATDLMEMAALADGIVLSPGPGKPSDAGLL
CEEEEECCCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCCCCHHHH
EEVVAKFAKEKPLLGICLGHQAIGEVFGGDVKRAAKIRHGKVSTMRQTAGAIFANLPEEM
HHHHHHHHHCCCEEEEECCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
PVMRYHSLIVDKNTLPQVLEVLAVATDDAEVMAMKVKDYPVYGLQFHPESIGTNDGKQMM
HHHHHHHHHHCCCCHHHHHHHHHHCCCCHHEEEEEECCCCEEEEEECCCCCCCCCHHHHH
ENFIHIVEGARENGNLTTKSI
HHHHHHHHCCCCCCCEECCCC
>Mature Secondary Structure
MILLIDNYDSFTFNLEQYLAEFSEVVVKRNDATDLMEMAALADGIVLSPGPGKPSDAGLL
CEEEEECCCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCCCCHHHH
EEVVAKFAKEKPLLGICLGHQAIGEVFGGDVKRAAKIRHGKVSTMRQTAGAIFANLPEEM
HHHHHHHHHCCCEEEEECCHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
PVMRYHSLIVDKNTLPQVLEVLAVATDDAEVMAMKVKDYPVYGLQFHPESIGTNDGKQMM
HHHHHHHHHHCCCCHHHHHHHHHHCCCCHHEEEEEECCCCEEEEEECCCCCCCCCHHHHH
ENFIHIVEGARENGNLTTKSI
HHHHHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]