Click here to switch to the map view.

The map label for this gene is argC

Identifier: 226224192

GI number: 226224192

Start: 1616425

End: 1617456

Strand: Reverse

Name: argC

Synonym: Lm4b_01602

Alternate gene names: 226224192

Gene position: 1617456-1616425 (Counterclockwise)

Preceding gene: 226224193

Following gene: 226224191

Centisome position: 55.53

GC content: 38.86

Gene sequence:

>1032_bases
ATGAAAGTTTCCATTATTGGTGCAACAGGATACGGAGGGCTTGAGCTAATTCGCTTGCTTCATCAACATGCTTCGGTAGA
CATAGCGACGTTACATAGTTTTTCCGCTCAATCAGAAACACTTGCAACCTTTTATCCTCATTTAAAAGATTTAGAAGCTA
GCCCCTTAGAGAAAATAAATTCAGCAGAAATCATCGAAAAAAGTGATACCGTTTTTATTGCCACGCCTTCTGGAATCGCG
AAAGATATTGCTCTCCCATATGTAGATGCAGGTTTGAATGTCATTGATCTATCCGGGGACTTTCGATTAAAAGACAGGCA
GCTTTACGAAAAATGGTACGGAAAAAGCGCGGCTCCAATCGAGTATATCGCTAAGGCGGAATATGGTTTAGCAGAATTCC
GTGATAAGAAAGAAGCTAGATTCATTGCTAATCCTGGATGTTATGCAACTGCAACTTTGTTAGGCATAGCACCTCTAGTG
AAAAGCCAGTTGATTGATCCAACATCGATTATCGTAGACGCTAAATCAGGTATTTCCGGCGCAGGAAAAGTGCCCTCTGC
AAGTACTCATTTTACAGAAACCAATGAAAACATGACACTTTATAAAATGAATTCTCATCAACATATTCCAGAAATTATGC
AACAATTAACTAAATGGGATGAGACTATCCCAGCAATTCAATTTTCTACTTCGTTAATTCCCATCACAAGAGGAATCTTC
ACAACCATCTACGTTAAACCCAAAAATCCTATCACCCAAAAAGAGTTACATACGCTTTACAAATCCACCTACGAGAATGC
TCCATTTGTCCGAATCCAACCAGAAAATGTATATCCTACTGTCAAACAAGTGACAGCATCGAATTACTGTGATATAGGTC
TTGCTTATAATGAAAAAACGAATGTGATTACTATCGTTTCTGTGCTTGATAATTTAGTTAAAGGGGCGGCTGGTCAGGCC
ATTCAAAATTTAAACATAATGGCGAATTTTGCTGAAAGTGACGGATTAAGGTTTATTCCGGTGTATCCGTGA

Upstream 100 bases:

>100_bases
CATAAAATAGTTTTAAATATTAATAAAAAACCATTTGACATTATAAATATACATCATTATAATGAAAAGTATCATTTAAT
AATTAACGGGAGGGGTTAGG

Downstream 100 bases:

>100_bases
AAGGGGAAAAATAAAATGGAACTTGTCAAAGGAAATATCGCTTCACCAAAAGGATTTTATGCTGACGGAAAACATGCAGG
GCTTAAAAGAAAACGAAATG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKVSIIGATGYGGLELIRLLHQHASVDIATLHSFSAQSETLATFYPHLKDLEASPLEKINSAEIIEKSDTVFIATPSGIA
KDIALPYVDAGLNVIDLSGDFRLKDRQLYEKWYGKSAAPIEYIAKAEYGLAEFRDKKEARFIANPGCYATATLLGIAPLV
KSQLIDPTSIIVDAKSGISGAGKVPSASTHFTETNENMTLYKMNSHQHIPEIMQQLTKWDETIPAIQFSTSLIPITRGIF
TTIYVKPKNPITQKELHTLYKSTYENAPFVRIQPENVYPTVKQVTASNYCDIGLAYNEKTNVITIVSVLDNLVKGAAGQA
IQNLNIMANFAESDGLRFIPVYP

Sequences:

>Translated_343_residues
MKVSIIGATGYGGLELIRLLHQHASVDIATLHSFSAQSETLATFYPHLKDLEASPLEKINSAEIIEKSDTVFIATPSGIA
KDIALPYVDAGLNVIDLSGDFRLKDRQLYEKWYGKSAAPIEYIAKAEYGLAEFRDKKEARFIANPGCYATATLLGIAPLV
KSQLIDPTSIIVDAKSGISGAGKVPSASTHFTETNENMTLYKMNSHQHIPEIMQQLTKWDETIPAIQFSTSLIPITRGIF
TTIYVKPKNPITQKELHTLYKSTYENAPFVRIQPENVYPTVKQVTASNYCDIGLAYNEKTNVITIVSVLDNLVKGAAGQA
IQNLNIMANFAESDGLRFIPVYP
>Mature_343_residues
MKVSIIGATGYGGLELIRLLHQHASVDIATLHSFSAQSETLATFYPHLKDLEASPLEKINSAEIIEKSDTVFIATPSGIA
KDIALPYVDAGLNVIDLSGDFRLKDRQLYEKWYGKSAAPIEYIAKAEYGLAEFRDKKEARFIANPGCYATATLLGIAPLV
KSQLIDPTSIIVDAKSGISGAGKVPSASTHFTETNENMTLYKMNSHQHIPEIMQQLTKWDETIPAIQFSTSLIPITRGIF
TTIYVKPKNPITQKELHTLYKSTYENAPFVRIQPENVYPTVKQVTASNYCDIGLAYNEKTNVITIVSVLDNLVKGAAGQA
IQNLNIMANFAESDGLRFIPVYP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=340, Percent_Identity=36.1764705882353, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320913, Length=351, Percent_Identity=27.9202279202279, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 37745; Mature: 37745

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01224 ARGC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSIIGATGYGGLELIRLLHQHASVDIATLHSFSAQSETLATFYPHLKDLEASPLEKIN
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEHHCCCCCCCHHHHHHCCHHCCCCCHHHHCC
SAEIIEKSDTVFIATPSGIAKDIALPYVDAGLNVIDLSGDFRLKDRQLYEKWYGKSAAPI
CHHEEECCCEEEEECCCCCHHHHCCCEECCCCEEEECCCCCEEHHHHHHHHHCCCCCCCH
EYIAKAEYGLAEFRDKKEARFIANPGCYATATLLGIAPLVKSQLIDPTSIIVDAKSGISG
HHHHHCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCC
AGKVPSASTHFTETNENMTLYKMNSHQHIPEIMQQLTKWDETIPAIQFSTSLIPITRGIF
CCCCCCCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHHCCEE
TTIYVKPKNPITQKELHTLYKSTYENAPFVRIQPENVYPTVKQVTASNYCDIGLAYNEKT
EEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCCEEEEEECCCC
NVITIVSVLDNLVKGAAGQAIQNLNIMANFAESDGLRFIPVYP
CEEEHHHHHHHHHHCHHHHHHHCCEEEEEECCCCCCEEEECCC
>Mature Secondary Structure
MKVSIIGATGYGGLELIRLLHQHASVDIATLHSFSAQSETLATFYPHLKDLEASPLEKIN
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEHHCCCCCCCHHHHHHCCHHCCCCCHHHHCC
SAEIIEKSDTVFIATPSGIAKDIALPYVDAGLNVIDLSGDFRLKDRQLYEKWYGKSAAPI
CHHEEECCCEEEEECCCCCHHHHCCCEECCCCEEEECCCCCEEHHHHHHHHHCCCCCCCH
EYIAKAEYGLAEFRDKKEARFIANPGCYATATLLGIAPLVKSQLIDPTSIIVDAKSGISG
HHHHHCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCC
AGKVPSASTHFTETNENMTLYKMNSHQHIPEIMQQLTKWDETIPAIQFSTSLIPITRGIF
CCCCCCCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHHCCEE
TTIYVKPKNPITQKELHTLYKSTYENAPFVRIQPENVYPTVKQVTASNYCDIGLAYNEKT
EEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHCCCCCEEEEEECCCC
NVITIVSVLDNLVKGAAGQAIQNLNIMANFAESDGLRFIPVYP
CEEEHHHHHHHHHHCHHHHHHHCCEEEEEECCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]