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The map label for this gene is argJ

Identifier: 226224191

GI number: 226224191

Start: 1615213

End: 1616409

Strand: Reverse

Name: argJ

Synonym: Lm4b_01601

Alternate gene names: 226224191

Gene position: 1616409-1615213 (Counterclockwise)

Preceding gene: 226224192

Following gene: 226224190

Centisome position: 55.5

GC content: 41.35

Gene sequence:

>1197_bases
ATGGAACTTGTCAAAGGAAATATCGCTTCACCAAAAGGATTTTATGCTGACGGAAAACATGCAGGGCTTAAAAGAAAACG
AAATGATATTGGTTGGATTTATTCAGAAGTTCCAGCAAATGCAGCCGCTGTTTATACGATGAATCAAATGCAAGCCGCAC
CAATTTTTGTAACGAAAGATTCTTTTCAAAGTAATGCGAAGTTACAAGCAATTATTGTGAATAGTGGGAATGCCAATGCA
TGTACAGGGAATCAAGGTATGTTAGATGCACTTGCGATGCGGGCTCAAACGGCAGAAAAGTTAGATATTCCACTTGATTA
CGTAGCCGTTGCTTCCACGGGAATTATTGGCGATATGCTACCGATGGACAAAATCAACGCGGGAATAGAAATGCTAGAAA
AGCAAACTGGAAATGCGGCCGATTTTGAAGAAGCGATTTTAACAACAGATACGTTTCAAAAACAAATCAGTTTTCAAACA
GAAATTGGTGGTAGAAAGGTAACGATGTCAGGTGTAGCGAAGGGATCAGGAATGATTCATCCAAATATGGCGACAATGCT
TGCTTTTATTACAACAGATGCCGCAATCCCGGCTGAATTATTGCAAAAATTACTAAAAATAAAAGTAGACAAAACTTTCA
ATCAAATAACGGTAGATGGCGATACTTCTACCAACGATATGGTGGTAGTCATGGCGAATGGCTGTGCAGAAAACCCGATG
CTTCAGGAAGGGACAGCGGATTTTGCGAAATTTGCGGATATGTTTCAAGCGGTAACGGAGCACCTTGCTAAAAGCATCGC
GCGAGACGGCGAGGGAGCGACAAAACTAATCGAGGTACAAGTTAATGGCGCTACAAAAACAGAAGATGCAAGAATGATTG
CTAAAAAAATTGTTTCCTCTAGTCTCGTGAAGACGGCAGCTTTTGGTGGAGATGGGAACTGGGGACGTATTATTTGCGCG
ATTGGCTATTCAGGTGGCCGGTTTGCGCCAGATAATATTACGATTAAAATTGGCGGGATTGAAATTCTGAATCATAGCAG
CCAAACCATTTTTAATCAACAGGCGTTAGATGCCTATTTAGAAGAAGAGCATATCATTATCGACGTTGATCTTCATATCG
GACTTGAGTCAGGAACAGCATGGGGTTGCGACTTGAGTTATGAATACGTCAAAATTAACGCATGCTACCGGACGTAA

Upstream 100 bases:

>100_bases
GGCTGGTCAGGCCATTCAAAATTTAAACATAATGGCGAATTTTGCTGAAAGTGACGGATTAAGGTTTATTCCGGTGTATC
CGTGAAAGGGGAAAAATAAA

Downstream 100 bases:

>100_bases
GGAGGAATCAGGATGGAGAATACGATAGTCGTAAAACTAGGCGGTGTCGCAAGTGACAATTTAACAGAAGATTTTTTCCA
ACAAATAATACAATGGCAAG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MELVKGNIASPKGFYADGKHAGLKRKRNDIGWIYSEVPANAAAVYTMNQMQAAPIFVTKDSFQSNAKLQAIIVNSGNANA
CTGNQGMLDALAMRAQTAEKLDIPLDYVAVASTGIIGDMLPMDKINAGIEMLEKQTGNAADFEEAILTTDTFQKQISFQT
EIGGRKVTMSGVAKGSGMIHPNMATMLAFITTDAAIPAELLQKLLKIKVDKTFNQITVDGDTSTNDMVVVMANGCAENPM
LQEGTADFAKFADMFQAVTEHLAKSIARDGEGATKLIEVQVNGATKTEDARMIAKKIVSSSLVKTAAFGGDGNWGRIICA
IGYSGGRFAPDNITIKIGGIEILNHSSQTIFNQQALDAYLEEEHIIIDVDLHIGLESGTAWGCDLSYEYVKINACYRT

Sequences:

>Translated_398_residues
MELVKGNIASPKGFYADGKHAGLKRKRNDIGWIYSEVPANAAAVYTMNQMQAAPIFVTKDSFQSNAKLQAIIVNSGNANA
CTGNQGMLDALAMRAQTAEKLDIPLDYVAVASTGIIGDMLPMDKINAGIEMLEKQTGNAADFEEAILTTDTFQKQISFQT
EIGGRKVTMSGVAKGSGMIHPNMATMLAFITTDAAIPAELLQKLLKIKVDKTFNQITVDGDTSTNDMVVVMANGCAENPM
LQEGTADFAKFADMFQAVTEHLAKSIARDGEGATKLIEVQVNGATKTEDARMIAKKIVSSSLVKTAAFGGDGNWGRIICA
IGYSGGRFAPDNITIKIGGIEILNHSSQTIFNQQALDAYLEEEHIIIDVDLHIGLESGTAWGCDLSYEYVKINACYRT
>Mature_398_residues
MELVKGNIASPKGFYADGKHAGLKRKRNDIGWIYSEVPANAAAVYTMNQMQAAPIFVTKDSFQSNAKLQAIIVNSGNANA
CTGNQGMLDALAMRAQTAEKLDIPLDYVAVASTGIIGDMLPMDKINAGIEMLEKQTGNAADFEEAILTTDTFQKQISFQT
EIGGRKVTMSGVAKGSGMIHPNMATMLAFITTDAAIPAELLQKLLKIKVDKTFNQITVDGDTSTNDMVVVMANGCAENPM
LQEGTADFAKFADMFQAVTEHLAKSIARDGEGATKLIEVQVNGATKTEDARMIAKKIVSSSLVKTAAFGGDGNWGRIICA
IGYSGGRFAPDNITIKIGGIEILNHSSQTIFNQQALDAYLEEEHIIIDVDLHIGLESGTAWGCDLSYEYVKINACYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=415, Percent_Identity=37.8313253012048, Blast_Score=254, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 42755; Mature: 42755

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVKGNIASPKGFYADGKHAGLKRKRNDIGWIYSEVPANAAAVYTMNQMQAAPIFVTKD
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEECCCCCCEEEEEECCCCCCEEEEECC
SFQSNAKLQAIIVNSGNANACTGNQGMLDALAMRAQTAEKLDIPLDYVAVASTGIIGDML
CCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCCC
PMDKINAGIEMLEKQTGNAADFEEAILTTDTFQKQISFQTEIGGRKVTMSGVAKGSGMIH
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCEEC
PNMATMLAFITTDAAIPAELLQKLLKIKVDKTFNQITVDGDTSTNDMVVVMANGCAENPM
CCHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCEEEECCCCCCCCEEEEEECCCCCCCC
LQEGTADFAKFADMFQAVTEHLAKSIARDGEGATKLIEVQVNGATKTEDARMIAKKIVSS
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
SLVKTAAFGGDGNWGRIICAIGYSGGRFAPDNITIKIGGIEILNHSSQTIFNQQALDAYL
HHHHHHCCCCCCCCCEEEEEEECCCCEECCCCEEEEECCEEEECCCCHHHHHHHHHHHHH
EEEHIIIDVDLHIGLESGTAWGCDLSYEYVKINACYRT
CCCEEEEEEEEEEEECCCCEECCCCEEEEEEEEEEECC
>Mature Secondary Structure
MELVKGNIASPKGFYADGKHAGLKRKRNDIGWIYSEVPANAAAVYTMNQMQAAPIFVTKD
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEECCCCCCEEEEEECCCCCCEEEEECC
SFQSNAKLQAIIVNSGNANACTGNQGMLDALAMRAQTAEKLDIPLDYVAVASTGIIGDML
CCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHCCC
PMDKINAGIEMLEKQTGNAADFEEAILTTDTFQKQISFQTEIGGRKVTMSGVAKGSGMIH
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCEEC
PNMATMLAFITTDAAIPAELLQKLLKIKVDKTFNQITVDGDTSTNDMVVVMANGCAENPM
CCHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCEEEECCCCCCCCEEEEEECCCCCCCC
LQEGTADFAKFADMFQAVTEHLAKSIARDGEGATKLIEVQVNGATKTEDARMIAKKIVSS
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
SLVKTAAFGGDGNWGRIICAIGYSGGRFAPDNITIKIGGIEILNHSSQTIFNQQALDAYL
HHHHHHCCCCCCCCCEEEEEEECCCCEECCCCEEEEECCEEEECCCCHHHHHHHHHHHHH
EEEHIIIDVDLHIGLESGTAWGCDLSYEYVKINACYRT
CCCEEEEEEEEEEEECCCCEECCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]