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The map label for this gene is ackA

Identifier: 226224182

GI number: 226224182

Start: 1606797

End: 1607990

Strand: Reverse

Name: ackA

Synonym: Lm4b_01592

Alternate gene names: 226224182

Gene position: 1607990-1606797 (Counterclockwise)

Preceding gene: 226224183

Following gene: 226224180

Centisome position: 55.21

GC content: 39.7

Gene sequence:

>1194_bases
ATGGAAAAAACGATTGCAATTAACGCCGGGAGTTCTTCACTGAAATTCCAATTATATGATATGCCATCTGAACGTGTTAT
CACAGCAGGGATTGTAGAAAGAATTGGTTTGAAAGATTCTATTTTTACAATTACTGTAGACGGAGAAAAAATCAAAGAAA
TTATTGATATTCCTGACCATGAAATTGCTGTTCAAATGCTACTTGAAAAATTAATTAACCACAAAGTTATCGGTTCTTAC
GATGAAATCACTGGAATTGGTCACCGCGTTGTTCACGGTGGAGAAAGATTCCCTGAATCCGTTTATATTGATGACCAAGT
AATTAAAGATATTGAAGCTCTATCTGAACTTGCGCCGCTTCATAACCCAGCGAACGTTACTGGTATTAAAGCATTCCGCA
AGATTTTACCAGATGTTGTTTCAGTGGCTGTTTTCGATACAGCTTTCCATCAAACAATGCCTCCAGCAAGTTATCTATAC
AGTCTGCCATACAGCTACTATGAAGACTATGGTATCCGTAAATACGGTTTCCACGGTACAAGTCACAAATATGTATCCGA
ACGCGCTGCAGAACTTTTAGGACGTCCTGTAGAAGAATTACGTTTACTAACTTGTCACCTTGGTAATGGTGCTAGTATCG
CTGCAATCGAAGGCGGAAAATCAATGGATACTTCCATGGGATTCACACCACTAGCTGGTGTTTCTATGGGAACTCGTTCT
GGTAACATTGACCCTGCGCTTATTCCTTTCATCATGGAAAAAACTGGCAAAACTGCAGAACAAGTACTTGATGTGTTAAA
CAAAGAATCTGGTATGCTTGGCGTATCTGGTATTTCAAGCGATCTTCGTGATTTAGAAGATGAAGCAGCAAAAGGAAACG
ACCGCGCAGAACTTGCACTTCAAGTTTTCGTTGACCGTATCCATAAATACATTGGTTCTTATGCAGCTCGTATGAACGGT
GTAGATGCCATTATCTTCACAGCTGGAATCGGTGAAAATAGTTCATACATCCGTGAAAAAGTACTTCGTGGACTTGAATT
CATGGGCGTATACTGGGATCCAGCACTTAACCAAGTGCGCGGAGAAGAAAGATTCCTTAACTATCCGCACTCCCCGGTAA
AAGTTATCATCATTCCTACAAACGAAGAATTAATGATTGCTCGTGATGTAGAAACAATTAAAAACAATCACTAA

Upstream 100 bases:

>100_bases
TCTCTTCGCTAACAGATCCGAGCGTAACTGCACCGATTTTAGCTGAAATAGAGAACTGGTTCAAAAGGAAACGATAATGG
AAGGAATTGACAAAAACAAA

Downstream 100 bases:

>100_bases
AAAAGAAAAAAAGGCTAGCTCTTAATTAAGAGCTAGCCTTTTTTTCTATCCTTATTTTTCTTCTTTATAATCAGGAACAT
CATTACGTACTACAAGAACA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase 1 [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MEKTIAINAGSSSLKFQLYDMPSERVITAGIVERIGLKDSIFTITVDGEKIKEIIDIPDHEIAVQMLLEKLINHKVIGSY
DEITGIGHRVVHGGERFPESVYIDDQVIKDIEALSELAPLHNPANVTGIKAFRKILPDVVSVAVFDTAFHQTMPPASYLY
SLPYSYYEDYGIRKYGFHGTSHKYVSERAAELLGRPVEELRLLTCHLGNGASIAAIEGGKSMDTSMGFTPLAGVSMGTRS
GNIDPALIPFIMEKTGKTAEQVLDVLNKESGMLGVSGISSDLRDLEDEAAKGNDRAELALQVFVDRIHKYIGSYAARMNG
VDAIIFTAGIGENSSYIREKVLRGLEFMGVYWDPALNQVRGEERFLNYPHSPVKVIIIPTNEELMIARDVETIKNNH

Sequences:

>Translated_397_residues
MEKTIAINAGSSSLKFQLYDMPSERVITAGIVERIGLKDSIFTITVDGEKIKEIIDIPDHEIAVQMLLEKLINHKVIGSY
DEITGIGHRVVHGGERFPESVYIDDQVIKDIEALSELAPLHNPANVTGIKAFRKILPDVVSVAVFDTAFHQTMPPASYLY
SLPYSYYEDYGIRKYGFHGTSHKYVSERAAELLGRPVEELRLLTCHLGNGASIAAIEGGKSMDTSMGFTPLAGVSMGTRS
GNIDPALIPFIMEKTGKTAEQVLDVLNKESGMLGVSGISSDLRDLEDEAAKGNDRAELALQVFVDRIHKYIGSYAARMNG
VDAIIFTAGIGENSSYIREKVLRGLEFMGVYWDPALNQVRGEERFLNYPHSPVKVIIIPTNEELMIARDVETIKNNH
>Mature_397_residues
MEKTIAINAGSSSLKFQLYDMPSERVITAGIVERIGLKDSIFTITVDGEKIKEIIDIPDHEIAVQMLLEKLINHKVIGSY
DEITGIGHRVVHGGERFPESVYIDDQVIKDIEALSELAPLHNPANVTGIKAFRKILPDVVSVAVFDTAFHQTMPPASYLY
SLPYSYYEDYGIRKYGFHGTSHKYVSERAAELLGRPVEELRLLTCHLGNGASIAAIEGGKSMDTSMGFTPLAGVSMGTRS
GNIDPALIPFIMEKTGKTAEQVLDVLNKESGMLGVSGISSDLRDLEDEAAKGNDRAELALQVFVDRIHKYIGSYAARMNG
VDAIIFTAGIGENSSYIREKVLRGLEFMGVYWDPALNQVRGEERFLNYPHSPVKVIIIPTNEELMIARDVETIKNNH

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=387, Percent_Identity=44.9612403100775, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1788633, Length=395, Percent_Identity=44.5569620253165, Blast_Score=328, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43831; Mature: 43831

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTIAINAGSSSLKFQLYDMPSERVITAGIVERIGLKDSIFTITVDGEKIKEIIDIPDH
CCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCH
EIAVQMLLEKLINHKVIGSYDEITGIGHRVVHGGERFPESVYIDDQVIKDIEALSELAPL
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHCC
HNPANVTGIKAFRKILPDVVSVAVFDTAFHQTMPPASYLYSLPYSYYEDYGIRKYGFHGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCEEECCCCC
SHKYVSERAAELLGRPVEELRLLTCHLGNGASIAAIEGGKSMDTSMGFTPLAGVSMGTRS
CHHHHHHHHHHHHCCCHHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCC
GNIDPALIPFIMEKTGKTAEQVLDVLNKESGMLGVSGISSDLRDLEDEAAKGNDRAELAL
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHH
QVFVDRIHKYIGSYAARMNGVDAIIFTAGIGENSSYIREKVLRGLEFMGVYWDPALNQVR
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHEEEEECHHHHHHC
GEERFLNYPHSPVKVIIIPTNEELMIARDVETIKNNH
CHHHHHCCCCCCEEEEEEECCCCEEEEECHHHHCCCC
>Mature Secondary Structure
MEKTIAINAGSSSLKFQLYDMPSERVITAGIVERIGLKDSIFTITVDGEKIKEIIDIPDH
CCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCH
EIAVQMLLEKLINHKVIGSYDEITGIGHRVVHGGERFPESVYIDDQVIKDIEALSELAPL
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHCCCCCCCCCCEEECHHHHHHHHHHHHHHCC
HNPANVTGIKAFRKILPDVVSVAVFDTAFHQTMPPASYLYSLPYSYYEDYGIRKYGFHGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCEEECCCCC
SHKYVSERAAELLGRPVEELRLLTCHLGNGASIAAIEGGKSMDTSMGFTPLAGVSMGTRS
CHHHHHHHHHHHHCCCHHHHEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCC
GNIDPALIPFIMEKTGKTAEQVLDVLNKESGMLGVSGISSDLRDLEDEAAKGNDRAELAL
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHH
QVFVDRIHKYIGSYAARMNGVDAIIFTAGIGENSSYIREKVLRGLEFMGVYWDPALNQVR
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHEEEEECHHHHHHC
GEERFLNYPHSPVKVIIIPTNEELMIARDVETIKNNH
CHHHHHCCCCCCEEEEEEECCCCEEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]