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The map label for this gene is accA

Identifier: 226224173

GI number: 226224173

Start: 1595148

End: 1596104

Strand: Reverse

Name: accA

Synonym: Lm4b_01583

Alternate gene names: 226224173

Gene position: 1596104-1595148 (Counterclockwise)

Preceding gene: 226224174

Following gene: 226224172

Centisome position: 54.8

GC content: 38.87

Gene sequence:

>957_bases
ATGGCGAATGAGATGGAATTTGAGAAACCGATTTTAGAATTAAAAAGTAAGATTGCTGACTTAAAAGAGTACAATGAAAC
TTCTGATGTGGATTTGACCAATGAAATTGAAAAGCTAGAAAAACGCTTAGCTAAGTTAGAATCAAGCATTTATAGCAATA
TGACTGCTTGGGATAAATTTCAAGTAGCTCGCCATCCAGAAAGACCTACGACACTTGATTATATTTCACTTTTGTTCGAA
GACTTCATGGAACTTCACGGGGATCGCGCATTTGGTGACGATGCTGCAATTGTTGGCGGTATCGCAACTTTCCACGGTAT
CCCAGTGACAGTTATTGGTCACCAACGTGGTAAAGATACAAAAGATAATTTACATCGTAATTTTGGTATGCCTCATCCTG
AAGGTTTCCGTAAAGCGCTACGTTTGATGAAACAAGCAGATAAATTTGGCCGACCAATTATTTGCTTCATCGATACGAAA
GGTGCTTATCCAGGTCGAGCTGCGGAAGAACGCGGTCAAAGTGAAGCCATTGCTAGAAATCTTTATGAAATGAGCGATAT
GAAAGTACCAATTATTTCTATTGTAATCGGTGAAGGTGGAAGTGGTGGAGCACTCGCTCTTGGTGTTGGAAATCAAATTT
TCATGCTTGAAAATGCAGTTTTCTCTGTTATTTCACCAGAAGGAGCAGCAGCTATTTTATGGAAAGATGCCAGTCAAGCG
AAGAAAGCAGCAGAGTCTATGCGGATTACAGCTGGCGATTTATTTGAACTTGGCATTACAGATGGAATTATTCCAGAAGT
AAAAGGCGGTGCGCACCGAGATTTAAATGCACAAGCCGAAGAAATTAACAAAACTATCACGAAGTCTTTACATGCACTAA
TGGCATTTTCTGAAGAACAATTAATAGAACAGCGTTATGAAAAATTCAAGAAAATCGGTGTATACGATACTTTATAA

Upstream 100 bases:

>100_bases
GGACAACTAGATGACTGTATTTCACGCCTTGATCTGCAAAATAAATTAAGTTTTATTTTAAGCATTCACGTGAAAACACC
TGAAGTAGGAGGTGAAGCGG

Downstream 100 bases:

>100_bases
ACAATAAAAGAAGCGGCTTTCCTAATTTTAGGAGATCCGCTTCTTTGGTATATGCCAAACGCTAAAAAGAAAGTTTACCC
ATTCACAAGTATAGACCAAT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MANEMEFEKPILELKSKIADLKEYNETSDVDLTNEIEKLEKRLAKLESSIYSNMTAWDKFQVARHPERPTTLDYISLLFE
DFMELHGDRAFGDDAAIVGGIATFHGIPVTVIGHQRGKDTKDNLHRNFGMPHPEGFRKALRLMKQADKFGRPIICFIDTK
GAYPGRAAEERGQSEAIARNLYEMSDMKVPIISIVIGEGGSGGALALGVGNQIFMLENAVFSVISPEGAAAILWKDASQA
KKAAESMRITAGDLFELGITDGIIPEVKGGAHRDLNAQAEEINKTITKSLHALMAFSEEQLIEQRYEKFKKIGVYDTL

Sequences:

>Translated_318_residues
MANEMEFEKPILELKSKIADLKEYNETSDVDLTNEIEKLEKRLAKLESSIYSNMTAWDKFQVARHPERPTTLDYISLLFE
DFMELHGDRAFGDDAAIVGGIATFHGIPVTVIGHQRGKDTKDNLHRNFGMPHPEGFRKALRLMKQADKFGRPIICFIDTK
GAYPGRAAEERGQSEAIARNLYEMSDMKVPIISIVIGEGGSGGALALGVGNQIFMLENAVFSVISPEGAAAILWKDASQA
KKAAESMRITAGDLFELGITDGIIPEVKGGAHRDLNAQAEEINKTITKSLHALMAFSEEQLIEQRYEKFKKIGVYDTL
>Mature_317_residues
ANEMEFEKPILELKSKIADLKEYNETSDVDLTNEIEKLEKRLAKLESSIYSNMTAWDKFQVARHPERPTTLDYISLLFED
FMELHGDRAFGDDAAIVGGIATFHGIPVTVIGHQRGKDTKDNLHRNFGMPHPEGFRKALRLMKQADKFGRPIICFIDTKG
AYPGRAAEERGQSEAIARNLYEMSDMKVPIISIVIGEGGSGGALALGVGNQIFMLENAVFSVISPEGAAAILWKDASQAK
KAAESMRITAGDLFELGITDGIIPEVKGGAHRDLNAQAEEINKTITKSLHALMAFSEEQLIEQRYEKFKKIGVYDTL

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=314, Percent_Identity=52.8662420382166, Blast_Score=338, Evalue=3e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 35264; Mature: 35133

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANEMEFEKPILELKSKIADLKEYNETSDVDLTNEIEKLEKRLAKLESSIYSNMTAWDKF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QVARHPERPTTLDYISLLFEDFMELHGDRAFGDDAAIVGGIATFHGIPVTVIGHQRGKDT
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
KDNLHRNFGMPHPEGFRKALRLMKQADKFGRPIICFIDTKGAYPGRAAEERGQSEAIARN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCHHHHHHHH
LYEMSDMKVPIISIVIGEGGSGGALALGVGNQIFMLENAVFSVISPEGAAAILWKDASQA
HHHHHCCCCEEEEEEEECCCCCCEEEEECCCEEEEEHHHHHHHCCCCCCEEEEECCHHHH
KKAAESMRITAGDLFELGITDGIIPEVKGGAHRDLNAQAEEINKTITKSLHALMAFSEEQ
HHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIEQRYEKFKKIGVYDTL
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANEMEFEKPILELKSKIADLKEYNETSDVDLTNEIEKLEKRLAKLESSIYSNMTAWDKF
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
QVARHPERPTTLDYISLLFEDFMELHGDRAFGDDAAIVGGIATFHGIPVTVIGHQRGKDT
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
KDNLHRNFGMPHPEGFRKALRLMKQADKFGRPIICFIDTKGAYPGRAAEERGQSEAIARN
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCHHHHHHHH
LYEMSDMKVPIISIVIGEGGSGGALALGVGNQIFMLENAVFSVISPEGAAAILWKDASQA
HHHHHCCCCEEEEEEEECCCCCCEEEEECCCEEEEEHHHHHHHCCCCCCEEEEECCHHHH
KKAAESMRITAGDLFELGITDGIIPEVKGGAHRDLNAQAEEINKTITKSLHALMAFSEEQ
HHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIEQRYEKFKKIGVYDTL
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]