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The map label for this gene is coaE

Identifier: 226224164

GI number: 226224164

Start: 1584055

End: 1584657

Strand: Reverse

Name: coaE

Synonym: Lm4b_01574

Alternate gene names: 226224164

Gene position: 1584657-1584055 (Counterclockwise)

Preceding gene: 226224165

Following gene: 226224163

Centisome position: 54.41

GC content: 36.65

Gene sequence:

>603_bases
ATGGGGAAAACGATTGGATTAACAGGAAGTGTAGCAACAGGGAAATCAACAGTGAGTAACATGATTCAGCAAGCGGGTAT
TCCATTAGTAGATGCAGATATTGCTGCTAGAAAAGTAGTGGAGCGTGGCACAGAAGGACTAAAAGAAATCGTTGCTTATT
TTGGGGAAGAAATTTTACTTGCAGATGGCACATTAAATCGAGCTAAATTAGGAGAAATTATTTTTAAAGATAAGGAAAAG
CGTGAAAAGTTAAATGAAATTACGCATCCACGTGTGAAAGACTATATGTTGGAAGCGCGCGAACGTTTTTTTGAAGCAGG
AGAGGAGCTTGTCTTTTTCGATATTCCGCTTTTGTTTGAAAGTCATTTAGAATCGTTGGTGGATAAAATAGTTGTTGTTT
GGACCACCCCTGAAACAGAGTTAAAACGCCTGATGGAGCGAAATAATCTAACAAAAGAAGATGCATTAAGAAGAATTGAA
AGCCAAATGGGAATCGATGAAAAGGCGAGAAAAGCTGATTTTGTCATCGATAATAATGAATCACTTGAAAAGACACAAAA
ACAAGTTCTTACATTTATCAAGCGTTTTGTAAAGAACAAATAG

Upstream 100 bases:

>100_bases
CCGTGTGTGGTTTGTGGAACGCCAATTGAAAAAATTAAATTAAACGGACGCGGGACACATTTTTGCCCGAATTGCCAAAA
ATAGAAAGCGAGCTGAAATC

Downstream 100 bases:

>100_bases
CCACCCTTACTTTCACATGGTATAATGAGGCATACAAATAAACAGATAGAGAAAGCTAGAGATAGGAGTGAGTTTTTGTG
AGATGTCCTACTTGTCAATA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MGKTIGLTGSVATGKSTVSNMIQQAGIPLVDADIAARKVVERGTEGLKEIVAYFGEEILLADGTLNRAKLGEIIFKDKEK
REKLNEITHPRVKDYMLEARERFFEAGEELVFFDIPLLFESHLESLVDKIVVVWTTPETELKRLMERNNLTKEDALRRIE
SQMGIDEKARKADFVIDNNESLEKTQKQVLTFIKRFVKNK

Sequences:

>Translated_200_residues
MGKTIGLTGSVATGKSTVSNMIQQAGIPLVDADIAARKVVERGTEGLKEIVAYFGEEILLADGTLNRAKLGEIIFKDKEK
REKLNEITHPRVKDYMLEARERFFEAGEELVFFDIPLLFESHLESLVDKIVVVWTTPETELKRLMERNNLTKEDALRRIE
SQMGIDEKARKADFVIDNNESLEKTQKQVLTFIKRFVKNK
>Mature_199_residues
GKTIGLTGSVATGKSTVSNMIQQAGIPLVDADIAARKVVERGTEGLKEIVAYFGEEILLADGTLNRAKLGEIIFKDKEKR
EKLNEITHPRVKDYMLEARERFFEAGEELVFFDIPLLFESHLESLVDKIVVVWTTPETELKRLMERNNLTKEDALRRIES
QMGIDEKARKADFVIDNNESLEKTQKQVLTFIKRFVKNK

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=187, Percent_Identity=41.7112299465241, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI191252795, Length=187, Percent_Identity=41.7112299465241, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI110227607, Length=189, Percent_Identity=30.1587301587302, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI110227605, Length=188, Percent_Identity=30.3191489361702, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI110227603, Length=188, Percent_Identity=30.3191489361702, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI110227601, Length=188, Percent_Identity=30.3191489361702, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI205277394, Length=188, Percent_Identity=30.3191489361702, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=35.3535353535354, Blast_Score=123, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17554944, Length=188, Percent_Identity=40.9574468085106, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI25143409, Length=195, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=202, Percent_Identity=40.0990099009901, Blast_Score=150, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24644728, Length=188, Percent_Identity=41.4893617021277, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24658602, Length=189, Percent_Identity=29.1005291005291, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22814; Mature: 22682

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTIGLTGSVATGKSTVSNMIQQAGIPLVDADIAARKVVERGTEGLKEIVAYFGEEILL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ADGTLNRAKLGEIIFKDKEKREKLNEITHPRVKDYMLEARERFFEAGEELVFFDIPLLFE
ECCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
SHLESLVDKIVVVWTTPETELKRLMERNNLTKEDALRRIESQMGIDEKARKADFVIDNNE
HHHHHHHHHEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCEEECCCH
SLEKTQKQVLTFIKRFVKNK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKTIGLTGSVATGKSTVSNMIQQAGIPLVDADIAARKVVERGTEGLKEIVAYFGEEILL
CCCCCCCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ADGTLNRAKLGEIIFKDKEKREKLNEITHPRVKDYMLEARERFFEAGEELVFFDIPLLFE
ECCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHH
SHLESLVDKIVVVWTTPETELKRLMERNNLTKEDALRRIESQMGIDEKARKADFVIDNNE
HHHHHHHHHEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCEEECCCH
SLEKTQKQVLTFIKRFVKNK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]