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The map label for this gene is nrdR

Identifier: 226224163

GI number: 226224163

Start: 1583513

End: 1583977

Strand: Reverse

Name: nrdR

Synonym: Lm4b_01573

Alternate gene names: 226224163

Gene position: 1583977-1583513 (Counterclockwise)

Preceding gene: 226224164

Following gene: 226224162

Centisome position: 54.38

GC content: 39.14

Gene sequence:

>465_bases
GTGAGATGTCCTACTTGTCAATATAATGGTACACGTGTTGTAGACTCAAGACCGGCAGATGATGGCAATTCCATCCGAAG
ACGGCGTGAATGTGAAAAATGCGGATTTCGTTTTACTACTTTTGAAAAGGTAGAAGAGAGTCCTTTAATAGTTGTGAAAA
AAGATGGAGCAAGAGAAGAATTCGCTCGTGAAAAAGTGCGACGCGGCTTAATAAGAGCATGTGAAAAACGACCAGTTAGC
GCTGAACAAATTGAAGAAATTGTCAATGAGGTAGAACGTGAACTGCGAAATATTGGAGACAGTGAAATCGCGTCTGACTT
AATTGGTGAAAAAGTGATGAATAAATTAGCGAATCTCGATGAAGTAGCCTACGTGCGCTTCGCTTCGGTGTATCGCCAAT
TTAAAGATATTAGTGTGTTTGTCGAAGAGTTAAAAGATTTAATGGAAAAAAATAAAGATAGGTGA

Upstream 100 bases:

>100_bases
AGCGTTTTGTAAAGAACAAATAGCCACCCTTACTTTCACATGGTATAATGAGGCATACAAATAAACAGATAGAGAAAGCT
AGAGATAGGAGTGAGTTTTT

Downstream 100 bases:

>100_bases
GTAAATTGACGGAATTTTGGATGGAGCTTCAAGCGGTAGACAGCTATCAAGTAAAAGCAAGTGGAATCTTGACCGGCGCC
GACAGAAAAATTATTACGAT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRCPTCQYNGTRVVDSRPADDGNSIRRRRECEKCGFRFTTFEKVEESPLIVVKKDGAREEFAREKVRRGLIRACEKRPVS
AEQIEEIVNEVERELRNIGDSEIASDLIGEKVMNKLANLDEVAYVRFASVYRQFKDISVFVEELKDLMEKNKDR

Sequences:

>Translated_154_residues
MRCPTCQYNGTRVVDSRPADDGNSIRRRRECEKCGFRFTTFEKVEESPLIVVKKDGAREEFAREKVRRGLIRACEKRPVS
AEQIEEIVNEVERELRNIGDSEIASDLIGEKVMNKLANLDEVAYVRFASVYRQFKDISVFVEELKDLMEKNKDR
>Mature_154_residues
MRCPTCQYNGTRVVDSRPADDGNSIRRRRECEKCGFRFTTFEKVEESPLIVVKKDGAREEFAREKVRRGLIRACEKRPVS
AEQIEEIVNEVERELRNIGDSEIASDLIGEKVMNKLANLDEVAYVRFASVYRQFKDISVFVEELKDLMEKNKDR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=49.6598639455782, Blast_Score=143, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17938; Mature: 17938

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPTCQYNGTRVVDSRPADDGNSIRRRRECEKCGFRFTTFEKVEESPLIVVKKDGAREE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCHHH
FAREKVRRGLIRACEKRPVSAEQIEEIVNEVERELRNIGDSEIASDLIGEKVMNKLANLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHH
EVAYVRFASVYRQFKDISVFVEELKDLMEKNKDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRCPTCQYNGTRVVDSRPADDGNSIRRRRECEKCGFRFTTFEKVEESPLIVVKKDGAREE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEECCCCHHH
FAREKVRRGLIRACEKRPVSAEQIEEIVNEVERELRNIGDSEIASDLIGEKVMNKLANLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHH
EVAYVRFASVYRQFKDISVFVEELKDLMEKNKDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]