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The map label for this gene is mreB

Identifier: 226224149

GI number: 226224149

Start: 1565475

End: 1566488

Strand: Reverse

Name: mreB

Synonym: Lm4b_01559

Alternate gene names: 226224149

Gene position: 1566488-1565475 (Counterclockwise)

Preceding gene: 226224150

Following gene: 226224148

Centisome position: 53.78

GC content: 37.67

Gene sequence:

>1014_bases
ATGTTTGGATTTGGTAATAAAGATATTGGAATTGATTTAGGAACAGCGAACACACTTGTCTATATGAAGGGAAAAGGTAT
TGTCCTTCGTGAACCTTCCGTTGTAGCAATGAAAAAAGACACTCAAGAAATAGTTGCAGTTGGTAGCGATGCAAAAAATA
TGATTGGTAGAACACCAGGAAATATCGTTGCAATTCGTCCAATGAAAGATGGTGTTATTGCTGATTATGATACAACTGCA
GCAATGATGAAGTATTACATACAAAAAGCTGGTAAAAGTGTTAATGCAAGTAAACCACGCGTAATGATATGTGTACCTTC
TGGAATTACAGGTGTAGAAAAACGTGCTGTTATTGATGCGACTCGTCAAGCAGGAGCTAAAGATGCATTTACAATTGAAG
AGCCATTTGCTGCGGCTATTGGTGCTGGGCTTCCAGTTGGCGAGCCTACAGGTAGCATGGTTGTAGATATTGGTGGAGGA
ACTACAGAAGTTGCTGTTATTTCTCTAGGTGGTATTGTAACCAGTCGCTCTGTAAGAACTGCTGGTGATGATTTAGATGA
AGTTATCATTAATTACATTCGTAAAAAATATAATCTATTAATTGGTGATCGTACTGCCGAAGCAATCAAAATGGAAATTG
GCTCAGCTAGTCCAAATGGTTTGGACTTATCTCCATTTAGCATTCGAGGACGTGATTTAGTAACTGGACTTCCTAAAACT
ATTGAAATTACTCCAGAAGAAATTAGCGAAGCACTTGCTGATACAGTAGCAGCGATTATTGATGCTGTAAAAGGAACACT
TGAAAATACGCCACCAGAATTGTCAGCTGATATTATGGATAAAGGTATTGTACTCACAGGTGGGGGAGCTCTTTTACGTA
ATTTAGATACAGTTATTTCCGAAGAAACAAAAATGCCTGTTATTATTGCAGATGAACCACTTGATTGTGTTGCAATTGGA
ACAGGGAAAGCTTTGGAAAATATGGATATGTATAAACGCAAAAAAATGAACTAA

Upstream 100 bases:

>100_bases
GAAACATTGACACAAAGGGATAAGGTAACATTAATTTAATGGACGAATAAGGAAACTTAATGTATCCTGTAGAATATTAC
GAAGGAAAAGGAGAATACAG

Downstream 100 bases:

>100_bases
ATGGACACGCTCATTTATGTCATATAACAAGATGAATTAGCTTCAAAAAAATGGAAAAAGAGTACTAACGAGATGAGGTG
TCGTTATGCCACAATTTTTT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MFGFGNKDIGIDLGTANTLVYMKGKGIVLREPSVVAMKKDTQEIVAVGSDAKNMIGRTPGNIVAIRPMKDGVIADYDTTA
AMMKYYIQKAGKSVNASKPRVMICVPSGITGVEKRAVIDATRQAGAKDAFTIEEPFAAAIGAGLPVGEPTGSMVVDIGGG
TTEVAVISLGGIVTSRSVRTAGDDLDEVIINYIRKKYNLLIGDRTAEAIKMEIGSASPNGLDLSPFSIRGRDLVTGLPKT
IEITPEEISEALADTVAAIIDAVKGTLENTPPELSADIMDKGIVLTGGGALLRNLDTVISEETKMPVIIADEPLDCVAIG
TGKALENMDMYKRKKMN

Sequences:

>Translated_337_residues
MFGFGNKDIGIDLGTANTLVYMKGKGIVLREPSVVAMKKDTQEIVAVGSDAKNMIGRTPGNIVAIRPMKDGVIADYDTTA
AMMKYYIQKAGKSVNASKPRVMICVPSGITGVEKRAVIDATRQAGAKDAFTIEEPFAAAIGAGLPVGEPTGSMVVDIGGG
TTEVAVISLGGIVTSRSVRTAGDDLDEVIINYIRKKYNLLIGDRTAEAIKMEIGSASPNGLDLSPFSIRGRDLVTGLPKT
IEITPEEISEALADTVAAIIDAVKGTLENTPPELSADIMDKGIVLTGGGALLRNLDTVISEETKMPVIIADEPLDCVAIG
TGKALENMDMYKRKKMN
>Mature_337_residues
MFGFGNKDIGIDLGTANTLVYMKGKGIVLREPSVVAMKKDTQEIVAVGSDAKNMIGRTPGNIVAIRPMKDGVIADYDTTA
AMMKYYIQKAGKSVNASKPRVMICVPSGITGVEKRAVIDATRQAGAKDAFTIEEPFAAAIGAGLPVGEPTGSMVVDIGGG
TTEVAVISLGGIVTSRSVRTAGDDLDEVIINYIRKKYNLLIGDRTAEAIKMEIGSASPNGLDLSPFSIRGRDLVTGLPKT
IEITPEEISEALADTVAAIIDAVKGTLENTPPELSADIMDKGIVLTGGGALLRNLDTVISEETKMPVIIADEPLDCVAIG
TGKALENMDMYKRKKMN

Specific function: Involved in formation of the rod shape of the cell [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=334, Percent_Identity=57.7844311377245, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1788875, Length=361, Percent_Identity=24.9307479224377, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 35490; Mature: 35490

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFGNKDIGIDLGTANTLVYMKGKGIVLREPSVVAMKKDTQEIVAVGSDAKNMIGRTPG
CCCCCCCCCEEEECCCCEEEEECCCEEEEECCCEEEEECCCHHHEEECCCHHHHHCCCCC
NIVAIRPMKDGVIADYDTTAAMMKYYIQKAGKSVNASKPRVMICVPSGITGVEKRAVIDA
CEEEEEECCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
TRQAGAKDAFTIEEPFAAAIGAGLPVGEPTGSMVVDIGGGTTEVAVISLGGIVTSRSVRT
HHHCCCCCCEEECCCHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEECCEEECCCCCC
AGDDLDEVIINYIRKKYNLLIGDRTAEAIKMEIGSASPNGLDLSPFSIRGRDLVTGLPKT
CCCCHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCCCCCCCCEECCCHHHCCCCCE
IEITPEEISEALADTVAAIIDAVKGTLENTPPELSADIMDKGIVLTGGGALLRNLDTVIS
EEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCEEEECCHHHHHHHHHHHC
EETKMPVIIADEPLDCVAIGTGKALENMDMYKRKKMN
CCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MFGFGNKDIGIDLGTANTLVYMKGKGIVLREPSVVAMKKDTQEIVAVGSDAKNMIGRTPG
CCCCCCCCCEEEECCCCEEEEECCCEEEEECCCEEEEECCCHHHEEECCCHHHHHCCCCC
NIVAIRPMKDGVIADYDTTAAMMKYYIQKAGKSVNASKPRVMICVPSGITGVEKRAVIDA
CEEEEEECCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
TRQAGAKDAFTIEEPFAAAIGAGLPVGEPTGSMVVDIGGGTTEVAVISLGGIVTSRSVRT
HHHCCCCCCEEECCCHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEECCEEECCCCCC
AGDDLDEVIINYIRKKYNLLIGDRTAEAIKMEIGSASPNGLDLSPFSIRGRDLVTGLPKT
CCCCHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCCCCCCCCEECCCHHHCCCCCE
IEITPEEISEALADTVAAIIDAVKGTLENTPPELSADIMDKGIVLTGGGALLRNLDTVIS
EEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCEEEECCHHHHHHHHHHHC
EETKMPVIIADEPLDCVAIGTGKALENMDMYKRKKMN
CCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377; 8387996 [H]