Click here to switch to the map view.

The map label for this gene is nadD

Identifier: 226224089

GI number: 226224089

Start: 1504360

End: 1504926

Strand: Reverse

Name: nadD

Synonym: Lm4b_01498

Alternate gene names: 226224089

Gene position: 1504926-1504360 (Counterclockwise)

Preceding gene: 226224090

Following gene: 226224088

Centisome position: 51.67

GC content: 38.98

Gene sequence:

>567_bases
ATGAAACATAAAGTCGGCATCTTAGGTGGGACTTTTGATCCGCCGCATTTAGCGCACCTCCGCATGGCAGAAGAGGCTAA
GAAGCAACTAGGACTTGAGAAAATTCTTTTTTTACCTAATAAAATTCCGCCTCATAAACATATCAGTGGTATGGCTTCAA
GTGATGAGCGTGTAGAAATGCTTCAATTAATGATAGAAGGTATAGATTCCTTTGAAATTGATACACGTGAACTCATGCGC
GCGGGAAAGTCCTATACGTATGACACAATGCGTGATATGATAAGCGAACAGCCGGATACAGATTTTTATTTCATTATCGG
CGGGGACATGGTAGAATATTTGCCAAAGTGGTATCATATAGATGACTTAGTAAAAATGGTGACATTCGTTGGGGTTAATC
GCCCCAGTTATCAGACGGAGGTTCCGTATGATATTGTTAAAATCAATATGCCAGAAACGACGATTTCTTCTACGGAAATT
AGAAATAATATTGAGAACGCGAGCACCTTTTTACCAGAAAAAGTATGGTCATATATAAAGGAGCATCAACTTTATGGAAA
GAAATGA

Upstream 100 bases:

>100_bases
GCGCGGAAATCGTTCAAGTCATTGGCAGAACGATTATTCTGTACAAAACTTCTGTAAACAAGCAACAAATTAAGTTGCCA
TAAATCGGGAGGAACCTACG

Downstream 100 bases:

>100_bases
AATGCTAAAAAAAGTAGAAGCAGCTATGCCTAATGCTCGATTTAAACACACTTTAGGCGTAGAAAAAGCAGCTGTAGAAC
TTGCAGAACATTATCATATG

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKHKVGILGGTFDPPHLAHLRMAEEAKKQLGLEKILFLPNKIPPHKHISGMASSDERVEMLQLMIEGIDSFEIDTRELMR
AGKSYTYDTMRDMISEQPDTDFYFIIGGDMVEYLPKWYHIDDLVKMVTFVGVNRPSYQTEVPYDIVKINMPETTISSTEI
RNNIENASTFLPEKVWSYIKEHQLYGKK

Sequences:

>Translated_188_residues
MKHKVGILGGTFDPPHLAHLRMAEEAKKQLGLEKILFLPNKIPPHKHISGMASSDERVEMLQLMIEGIDSFEIDTRELMR
AGKSYTYDTMRDMISEQPDTDFYFIIGGDMVEYLPKWYHIDDLVKMVTFVGVNRPSYQTEVPYDIVKINMPETTISSTEI
RNNIENASTFLPEKVWSYIKEHQLYGKK
>Mature_188_residues
MKHKVGILGGTFDPPHLAHLRMAEEAKKQLGLEKILFLPNKIPPHKHISGMASSDERVEMLQLMIEGIDSFEIDTRELMR
AGKSYTYDTMRDMISEQPDTDFYFIIGGDMVEYLPKWYHIDDLVKMVTFVGVNRPSYQTEVPYDIVKINMPETTISSTEI
RNNIENASTFLPEKVWSYIKEHQLYGKK

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) [H]

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family [H]

Homologues:

Organism=Escherichia coli, GI1786858, Length=213, Percent_Identity=33.8028169014084, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.18 [H]

Molecular weight: Translated: 21772; Mature: 21772

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHKVGILGGTFDPPHLAHLRMAEEAKKQLGLEKILFLPNKIPPHKHISGMASSDERVEM
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHCCCCCCHHHHHH
LQLMIEGIDSFEIDTRELMRAGKSYTYDTMRDMISEQPDTDFYFIIGGDMVEYLPKWYHI
HHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCH
DDLVKMVTFVGVNRPSYQTEVPYDIVKINMPETTISSTEIRNNIENASTFLPEKVWSYIK
HHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHQLYGKK
HHHHCCCC
>Mature Secondary Structure
MKHKVGILGGTFDPPHLAHLRMAEEAKKQLGLEKILFLPNKIPPHKHISGMASSDERVEM
CCCCEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHCCCCCCHHHHHH
LQLMIEGIDSFEIDTRELMRAGKSYTYDTMRDMISEQPDTDFYFIIGGDMVEYLPKWYHI
HHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHCCH
DDLVKMVTFVGVNRPSYQTEVPYDIVKINMPETTISSTEIRNNIENASTFLPEKVWSYIK
HHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHQLYGKK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]