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The map label for this gene is sod

Identifier: 226224040

GI number: 226224040

Start: 1456672

End: 1457280

Strand: Reverse

Name: sod

Synonym: Lm4b_01449

Alternate gene names: 226224040

Gene position: 1457280-1456672 (Counterclockwise)

Preceding gene: 226224045

Following gene: 226224039

Centisome position: 50.03

GC content: 39.9

Gene sequence:

>609_bases
ATGACTTACGAATTACCTAAATTACCTTATACTTATGATGCTTTGGAGCCGAATTTTGATAAAGAAACTATGGAAATTCA
CTATACAAAGCACCACAATACTTATGTGACAAAACTAAATGAAGCGGTTGCTGGTCATCCTGAACTTGCAAGCAAATCTG
TGGAAGAATTAGTAGCTAACTTAGATAGCGTTCCTGAAGATATTCGCGGCGCTGTCCGTAACCACGGTGGCGGTCATGCT
AACCATACATTATTCTGGTCTATTCTTAGCCCAAATGGTGGCGGCGCTCCAACTGGTAATTTAAAAGCAGCAATCGAAAG
CGAATTCGGTACTTTTGACGAATTTAAAGAAAAATTCAATGCAGCTGCTGCAGCACGTTTTGGTTCTGGCTGGGCTTGGC
TAGTAGTTAATGATGGCAAATTAGAAATCGTTTCTACAGCTAACCAAGATTCTCCACTAAGCGATGGCAAAACACCTGTT
CTTGGCTTAGATGTTTGGGAACATGCTTACTACCTTAAATTCCAAAATCGTCGTCCTGAATATATCGACACATTTTGGAA
TGTTATTAACTGGGATGAAGCTAACAAACGTTTTGACGCAGCTAAATAA

Upstream 100 bases:

>100_bases
GTTTTTAAGGTTGATAGTAGTTCTATTGAAATAGGACATGAAACTTTTGCCTTATACGTCATTTCTTTTCACGTAAAAAC
AATACAAGGAGGAATTTTTA

Downstream 100 bases:

>100_bases
TAATCACAAGACTCACTTCGGTGGGTCTTTTTTTATTTCTAATGAATTTCTAATGAACTTACAGTGGAAAAATCATGTTA
TTTCAGCTACAATAGGGAAA

Product: superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MTYELPKLPYTYDALEPNFDKETMEIHYTKHHNTYVTKLNEAVAGHPELASKSVEELVANLDSVPEDIRGAVRNHGGGHA
NHTLFWSILSPNGGGAPTGNLKAAIESEFGTFDEFKEKFNAAAAARFGSGWAWLVVNDGKLEIVSTANQDSPLSDGKTPV
LGLDVWEHAYYLKFQNRRPEYIDTFWNVINWDEANKRFDAAK

Sequences:

>Translated_202_residues
MTYELPKLPYTYDALEPNFDKETMEIHYTKHHNTYVTKLNEAVAGHPELASKSVEELVANLDSVPEDIRGAVRNHGGGHA
NHTLFWSILSPNGGGAPTGNLKAAIESEFGTFDEFKEKFNAAAAARFGSGWAWLVVNDGKLEIVSTANQDSPLSDGKTPV
LGLDVWEHAYYLKFQNRRPEYIDTFWNVINWDEANKRFDAAK
>Mature_201_residues
TYELPKLPYTYDALEPNFDKETMEIHYTKHHNTYVTKLNEAVAGHPELASKSVEELVANLDSVPEDIRGAVRNHGGGHAN
HTLFWSILSPNGGGAPTGNLKAAIESEFGTFDEFKEKFNAAAAARFGSGWAWLVVNDGKLEIVSTANQDSPLSDGKTPVL
GLDVWEHAYYLKFQNRRPEYIDTFWNVINWDEANKRFDAAK

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=204, Percent_Identity=46.5686274509804, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI67782305, Length=204, Percent_Identity=46.5686274509804, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI67782309, Length=204, Percent_Identity=37.2549019607843, Blast_Score=137, Evalue=7e-33,
Organism=Escherichia coli, GI1790342, Length=208, Percent_Identity=60.5769230769231, Blast_Score=259, Evalue=7e-71,
Organism=Escherichia coli, GI1787946, Length=201, Percent_Identity=47.7611940298507, Blast_Score=194, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17506561, Length=205, Percent_Identity=41.4634146341463, Blast_Score=163, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17569479, Length=203, Percent_Identity=39.4088669950739, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321796, Length=204, Percent_Identity=43.1372549019608, Blast_Score=167, Evalue=9e-43,
Organism=Drosophila melanogaster, GI17136812, Length=204, Percent_Identity=46.5686274509804, Blast_Score=179, Evalue=1e-45,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 22615; Mature: 22484

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYELPKLPYTYDALEPNFDKETMEIHYTKHHNTYVTKLNEAVAGHPELASKSVEELVAN
CCCCCCCCCCEECCCCCCCCCCEEEEEEEECCCEEEEEHHHHHCCCHHHHHHHHHHHHHH
LDSVPEDIRGAVRNHGGGHANHTLFWSILSPNGGGAPTGNLKAAIESEFGTFDEFKEKFN
HCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHH
AAAAARFGSGWAWLVVNDGKLEIVSTANQDSPLSDGKTPVLGLDVWEHAYYLKFQNRRPE
HHHHHHCCCCEEEEEEECCEEEEEEECCCCCCCCCCCCCEEEEEHHCCEEEEEECCCCCH
YIDTFWNVINWDEANKRFDAAK
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TYELPKLPYTYDALEPNFDKETMEIHYTKHHNTYVTKLNEAVAGHPELASKSVEELVAN
CCCCCCCCCEECCCCCCCCCCEEEEEEEECCCEEEEEHHHHHCCCHHHHHHHHHHHHHH
LDSVPEDIRGAVRNHGGGHANHTLFWSILSPNGGGAPTGNLKAAIESEFGTFDEFKEKFN
HCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHH
AAAAARFGSGWAWLVVNDGKLEIVSTANQDSPLSDGKTPVLGLDVWEHAYYLKFQNRRPE
HHHHHHCCCCEEEEEEECCEEEEEEECCCCCCCCCCCCCEEEEEHHCCEEEEEECCCCCH
YIDTFWNVINWDEANKRFDAAK
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]