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The map label for this gene is yqgF [H]

Identifier: 226224039

GI number: 226224039

Start: 1454377

End: 1456542

Strand: Reverse

Name: yqgF [H]

Synonym: Lm4b_01448

Alternate gene names: 226224039

Gene position: 1456542-1454377 (Counterclockwise)

Preceding gene: 226224040

Following gene: 226224038

Centisome position: 50.01

GC content: 37.77

Gene sequence:

>2166_bases
GTGAAACTAAATTTTAGAAAAAAGAAAAAAGATTCCACTAAGAAGAAACGCGCCATCATTCCACTACGTTTAAATATTCT
ATTCTTTATTATTTTTATATTATTCTCCGTGTTAATTTTACGTCTTGGTATTGTTCAAATTGTGCAAGGGGATACGTACA
AACGTCAATTAGAAGAAACAGATAACGTAACAGTTTCCAAAAACGTACCACGTGGTAGCATTTATGACCGAAATTACAAT
TTGCTGGTTGGTAATTCAGCGGTTAAATCTATTACTTACACACGTAGTCAACAAACACAGACTGCAGAAACTCTACATGT
AGCCCAAACATTAGAAAAGCTAATTACTGTCGAGCCTGAAAAGTTAACTGACCGTGATTTGAAAGATTACTGGATTTTAA
CGCATCAAACCGAATCGCTAAACCGCTTATCAGCGAAAGAACAAGCGCTTGATTCATCTAAAGCCTACAAAATCCAAGTT
GACAAAGTGACAAAAGAAGATATCGCTAGCTTGACCAGTGAAGACTTAAAAGTAGCAACCATCTATAAAAAAATGACAAC
TGGATATGCTATGACTGAATCTGTTGTGAAAAATAAAGATGTAACAGACGAAGAAATCGCACGTGTCAGTGAAAATATGG
ACAGTTTACCTGGTGTAGATACTACTACAGACTGGAATCGTTATTACACATATGATGAAACTTTACGCTCAATTTTAGGT
TCTGTTTCCACAGCTAAAGAAGGTCTACCAAAAGACAAAGCGGAATACTACTTATCTCAAGGATATAGTCGTAATGATCG
CGTTGGTAAAAGCTATCTAGAAGCTCAATATGAAAGTGTGCTCGCTGGATCAAAATCTCAATCAGAAAGCGTACTTGATT
CTAAAGGTAATATTATTGAAACTGTCAACAAATACGAAGGCTCCAAAGGGAAAGATTTAGTTCTTTCTGTTGATGTTGAA
TTTCAAAAAGCAGTAGAAGAAATTCTCAAAAAAAACATCAAACAAGGTAAACAATATGCTGGTTCAGATTTATTTGACCG
CGCATTCGTTGTTGCCATGGATCCATATTCCGGAGAAGTCCTTGCACTAGCAGGACAGAAACTAAATGACAAGGGTGAGT
TTGAAGATTATTCCCTTGGTACATTTACAACTGCCTACGCAATGGGCTCTGCTGTCAAAGGTTCTACTATCCTTGGTGGT
ATTATGGACGGTGCTATTACAAACAAAACTGTTTTCACTGACCAACCAATTGTACTAAAAGGAACAAAACCAAAGAGCTC
ATGGTTTAACAGAACCGGAGCTGGTAATAGACCACTTGATCCTGTAGGAGCTTTAGAAATTTCTTCTAACTCCTATATGT
ACCAAGTTGCAATGAAAATGGGTGGCGCAAACTATGTACCAAACGGACCTCTTAGAGCACCACTTAGCACCTTTGACGAT
ATGCGTTACTACTACAACCAATTCGGTCTAGGTGTAAAAACTGGCATCGACCTTCCAGGTGAACAAACTGGTTATAAAGG
GGACGACCAAACAATCGGTAAAATTCTCGATTTCGCTATCGGACAATATGACTCCTACACACCACTTCAAATGGCTCAAT
ATGTTTCTACTATTGCCAATGGGGGCTCAAGAATCGCTCCTAGTATGGTAAAAGAAATTAGAAATCCAAGTACTAATGGT
GACTCTGTCGGAACACTTGCAACAGCTAATGAACCAAAAGTATTAAATAAAATCGGTGTTTCTGAAAGTGATATCAAAAC
AGTACAACAAGGCTTCTATGAAGTAACACATGGTTCAACAGGTACCGCAAGAACTGTTTTCACTTCAAGTGATTACGATG
TCGCTGGTAAAACAGGCACCGCAGATGCGTTCTATGATGGACCAAAAGAAGGTAACAAAATGGCCAGTGTTTGGAATACA
ACATTCGTCGGTTATGCGCCAGTGGAAAAACCGGAAATAGCAATTTCCGTTGTTGTTCCTTGGATTTATCGTCCATATGG
TACGGACCAAAAAACAAATATGAAAATCTCCAAAGAAGTATTCGACAAATACTTCGAACTTAAAAAAGAACGCTCTGAAT
CGAAAAAAGATACTTCAAAAGTAGAACAACCAATTAACAACAAAGAAGCTGCTGCGAAAGCACAATCAGAACAAACCGAA
AATTAA

Upstream 100 bases:

>100_bases
TTTTTATTTCTAATGAATTTCTAATGAACTTACAGTGGAAAAATCATGTTATTTCAGCTACAATAGGGAAAGGTATTATT
GAAAAGTGAGGTAACTATGC

Downstream 100 bases:

>100_bases
TCAAAAACCACTTTCATTTATTTGGAAGTGGTTTTTTTATTTCAAACTAACAAACAATTTAAAAAAATAGTTGCTAATGC
GTAGAAAAAACTGCGAAAAG

Product: penicillin-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 721; Mature: 721

Protein sequence:

>721_residues
MKLNFRKKKKDSTKKKRAIIPLRLNILFFIIFILFSVLILRLGIVQIVQGDTYKRQLEETDNVTVSKNVPRGSIYDRNYN
LLVGNSAVKSITYTRSQQTQTAETLHVAQTLEKLITVEPEKLTDRDLKDYWILTHQTESLNRLSAKEQALDSSKAYKIQV
DKVTKEDIASLTSEDLKVATIYKKMTTGYAMTESVVKNKDVTDEEIARVSENMDSLPGVDTTTDWNRYYTYDETLRSILG
SVSTAKEGLPKDKAEYYLSQGYSRNDRVGKSYLEAQYESVLAGSKSQSESVLDSKGNIIETVNKYEGSKGKDLVLSVDVE
FQKAVEEILKKNIKQGKQYAGSDLFDRAFVVAMDPYSGEVLALAGQKLNDKGEFEDYSLGTFTTAYAMGSAVKGSTILGG
IMDGAITNKTVFTDQPIVLKGTKPKSSWFNRTGAGNRPLDPVGALEISSNSYMYQVAMKMGGANYVPNGPLRAPLSTFDD
MRYYYNQFGLGVKTGIDLPGEQTGYKGDDQTIGKILDFAIGQYDSYTPLQMAQYVSTIANGGSRIAPSMVKEIRNPSTNG
DSVGTLATANEPKVLNKIGVSESDIKTVQQGFYEVTHGSTGTARTVFTSSDYDVAGKTGTADAFYDGPKEGNKMASVWNT
TFVGYAPVEKPEIAISVVVPWIYRPYGTDQKTNMKISKEVFDKYFELKKERSESKKDTSKVEQPINNKEAAAKAQSEQTE
N

Sequences:

>Translated_721_residues
MKLNFRKKKKDSTKKKRAIIPLRLNILFFIIFILFSVLILRLGIVQIVQGDTYKRQLEETDNVTVSKNVPRGSIYDRNYN
LLVGNSAVKSITYTRSQQTQTAETLHVAQTLEKLITVEPEKLTDRDLKDYWILTHQTESLNRLSAKEQALDSSKAYKIQV
DKVTKEDIASLTSEDLKVATIYKKMTTGYAMTESVVKNKDVTDEEIARVSENMDSLPGVDTTTDWNRYYTYDETLRSILG
SVSTAKEGLPKDKAEYYLSQGYSRNDRVGKSYLEAQYESVLAGSKSQSESVLDSKGNIIETVNKYEGSKGKDLVLSVDVE
FQKAVEEILKKNIKQGKQYAGSDLFDRAFVVAMDPYSGEVLALAGQKLNDKGEFEDYSLGTFTTAYAMGSAVKGSTILGG
IMDGAITNKTVFTDQPIVLKGTKPKSSWFNRTGAGNRPLDPVGALEISSNSYMYQVAMKMGGANYVPNGPLRAPLSTFDD
MRYYYNQFGLGVKTGIDLPGEQTGYKGDDQTIGKILDFAIGQYDSYTPLQMAQYVSTIANGGSRIAPSMVKEIRNPSTNG
DSVGTLATANEPKVLNKIGVSESDIKTVQQGFYEVTHGSTGTARTVFTSSDYDVAGKTGTADAFYDGPKEGNKMASVWNT
TFVGYAPVEKPEIAISVVVPWIYRPYGTDQKTNMKISKEVFDKYFELKKERSESKKDTSKVEQPINNKEAAAKAQSEQTE
N
>Mature_721_residues
MKLNFRKKKKDSTKKKRAIIPLRLNILFFIIFILFSVLILRLGIVQIVQGDTYKRQLEETDNVTVSKNVPRGSIYDRNYN
LLVGNSAVKSITYTRSQQTQTAETLHVAQTLEKLITVEPEKLTDRDLKDYWILTHQTESLNRLSAKEQALDSSKAYKIQV
DKVTKEDIASLTSEDLKVATIYKKMTTGYAMTESVVKNKDVTDEEIARVSENMDSLPGVDTTTDWNRYYTYDETLRSILG
SVSTAKEGLPKDKAEYYLSQGYSRNDRVGKSYLEAQYESVLAGSKSQSESVLDSKGNIIETVNKYEGSKGKDLVLSVDVE
FQKAVEEILKKNIKQGKQYAGSDLFDRAFVVAMDPYSGEVLALAGQKLNDKGEFEDYSLGTFTTAYAMGSAVKGSTILGG
IMDGAITNKTVFTDQPIVLKGTKPKSSWFNRTGAGNRPLDPVGALEISSNSYMYQVAMKMGGANYVPNGPLRAPLSTFDD
MRYYYNQFGLGVKTGIDLPGEQTGYKGDDQTIGKILDFAIGQYDSYTPLQMAQYVSTIANGGSRIAPSMVKEIRNPSTNG
DSVGTLATANEPKVLNKIGVSESDIKTVQQGFYEVTHGSTGTARTVFTSSDYDVAGKTGTADAFYDGPKEGNKMASVWNT
TFVGYAPVEKPEIAISVVVPWIYRPYGTDQKTNMKISKEVFDKYFELKKERSESKKDTSKVEQPINNKEAAAKAQSEQTE
N

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=715, Percent_Identity=25.034965034965, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786272, Length=451, Percent_Identity=23.9467849223947, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 79917; Mature: 79917

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNFRKKKKDSTKKKRAIIPLRLNILFFIIFILFSVLILRLGIVQIVQGDTYKRQLEET
CCCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
DNVTVSKNVPRGSIYDRNYNLLVGNSAVKSITYTRSQQTQTAETLHVAQTLEKLITVEPE
CCEEEECCCCCCCEECCCCEEEECCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCH
KLTDRDLKDYWILTHQTESLNRLSAKEQALDSSKAYKIQVDKVTKEDIASLTSEDLKVAT
HHCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCHHH
IYKKMTTGYAMTESVVKNKDVTDEEIARVSENMDSLPGVDTTTDWNRYYTYDETLRSILG
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHH
SVSTAKEGLPKDKAEYYLSQGYSRNDRVGKSYLEAQYESVLAGSKSQSESVLDSKGNIIE
HHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHH
TVNKYEGSKGKDLVLSVDVEFQKAVEEILKKNIKQGKQYAGSDLFDRAFVVAMDPYSGEV
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEEECCCCCCE
LALAGQKLNDKGEFEDYSLGTFTTAYAMGSAVKGSTILGGIMDGAITNKTVFTDQPIVLK
EEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEE
GTKPKSSWFNRTGAGNRPLDPVGALEISSNSYMYQVAMKMGGANYVPNGPLRAPLSTFDD
CCCCCHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEEEHHCCCCCCCCCCCCCCHHHHHH
MRYYYNQFGLGVKTGIDLPGEQTGYKGDDQTIGKILDFAIGQYDSYTPLQMAQYVSTIAN
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GGSRIAPSMVKEIRNPSTNGDSVGTLATANEPKVLNKIGVSESDIKTVQQGFYEVTHGST
CCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHEECCCCC
GTARTVFTSSDYDVAGKTGTADAFYDGPKEGNKMASVWNTTFVGYAPVEKPEIAISVVVP
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCCCEEEEEEEC
WIYRPYGTDQKTNMKISKEVFDKYFELKKERSESKKDTSKVEQPINNKEAAAKAQSEQTE
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
N
C
>Mature Secondary Structure
MKLNFRKKKKDSTKKKRAIIPLRLNILFFIIFILFSVLILRLGIVQIVQGDTYKRQLEET
CCCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
DNVTVSKNVPRGSIYDRNYNLLVGNSAVKSITYTRSQQTQTAETLHVAQTLEKLITVEPE
CCEEEECCCCCCCEECCCCEEEECCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCH
KLTDRDLKDYWILTHQTESLNRLSAKEQALDSSKAYKIQVDKVTKEDIASLTSEDLKVAT
HHCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCHHH
IYKKMTTGYAMTESVVKNKDVTDEEIARVSENMDSLPGVDTTTDWNRYYTYDETLRSILG
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHH
SVSTAKEGLPKDKAEYYLSQGYSRNDRVGKSYLEAQYESVLAGSKSQSESVLDSKGNIIE
HHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHH
TVNKYEGSKGKDLVLSVDVEFQKAVEEILKKNIKQGKQYAGSDLFDRAFVVAMDPYSGEV
HHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEEECCCCCCE
LALAGQKLNDKGEFEDYSLGTFTTAYAMGSAVKGSTILGGIMDGAITNKTVFTDQPIVLK
EEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEE
GTKPKSSWFNRTGAGNRPLDPVGALEISSNSYMYQVAMKMGGANYVPNGPLRAPLSTFDD
CCCCCHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEEEHHCCCCCCCCCCCCCCHHHHHH
MRYYYNQFGLGVKTGIDLPGEQTGYKGDDQTIGKILDFAIGQYDSYTPLQMAQYVSTIAN
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GGSRIAPSMVKEIRNPSTNGDSVGTLATANEPKVLNKIGVSESDIKTVQQGFYEVTHGST
CCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHEECCCCC
GTARTVFTSSDYDVAGKTGTADAFYDGPKEGNKMASVWNTTFVGYAPVEKPEIAISVVVP
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCCCEEEEEEEC
WIYRPYGTDQKTNMKISKEVFDKYFELKKERSESKKDTSKVEQPINNKEAAAKAQSEQTE
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]