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The map label for this gene is cdsA

Identifier: 226223917

GI number: 226223917

Start: 1325559

End: 1326347

Strand: Direct

Name: cdsA

Synonym: Lm4b_01324

Alternate gene names: 226223917

Gene position: 1325559-1326347 (Clockwise)

Preceding gene: 226223916

Following gene: 226223918

Centisome position: 45.51

GC content: 34.47

Gene sequence:

>789_bases
TTGAAAACGAGAATTATTACTGCAGTTGTTGCGCTTATATTTTTTATTCCATTCGTTGTCTACGGAGGAATTCCATTTGA
ACTATTAAGTATTTTACTAGCAACGATTGCTTTATATGAAGTACTTGTAATGACAAAACAACGAATTTTTTCGATGAATG
GAATAATTACTTTACTATTAATGTGGTTAGTTGTCGTGCCAGATAGATATTTGGACTTTTTAGATACACTGCATATTACT
GAAATGGAAGTTATTTTTATTTTAATGGCTTTATTACTCGCTAATACTGTATTTTCACGAAATAAATTCCATTTTGATCA
AGTTGGTATTTGTATGGTTGCCGCTTTTTATACAGGATTTGGTTTCCATTACTTGGCATTAACTCGTGAAGCTGGGTTAA
TGTATGTACTTTTTGCTTTATTTATTGTTTGGTCAACTGATACAGGGGCTTATTTTATTGGAAAAGCGATTGGAAAACAC
AAATTAGCTCCGAATGTTAGCCCAAACAAAACGGTGGAAGGGTTTATCGGCGGGATTGTATGTGCACTTGTCATTGCTGG
GGGCTTTTATTATTTTGCTGAGCTACCAGGAAATATTGCACTCGTACTAGCGCTTTTAGTTTTTCTTTCTATTTTTGGAC
AGTTGGGAGACTTGGTCGAATCTGCTTTGAAACGCTTTTATGGTGTAAAAGATTCTGGGAAAATCTTACCAGGGCATGGT
GGTATTTTAGACCGCTTTGATAGCTTGTTGTTCGTTTTACCTCTGCTACATATACTTCAAATTATTTAA

Upstream 100 bases:

>100_bases
ACACATTGGCCTGATTTTTCAAAAGAAGATTTTTTACAGGCAATTATTGAATATCAAAACCGGTCACGTCGTTTTGGAGG
GCTCTAGGGAGGAAAAAAGA

Downstream 100 bases:

>100_bases
TTGGAGATGGGATAATGAAAAAAATTATTTTGCTAGGTGCAACTGGTTCTATTGGAACACAAACGCTTGCAATCATTCGC
GAAAACCCTGAAAAATTTCA

Product: phosphatidate cytidylyltransferase (CDP-diglyceride synthase)

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKTRIITAVVALIFFIPFVVYGGIPFELLSILLATIALYEVLVMTKQRIFSMNGIITLLLMWLVVVPDRYLDFLDTLHIT
EMEVIFILMALLLANTVFSRNKFHFDQVGICMVAAFYTGFGFHYLALTREAGLMYVLFALFIVWSTDTGAYFIGKAIGKH
KLAPNVSPNKTVEGFIGGIVCALVIAGGFYYFAELPGNIALVLALLVFLSIFGQLGDLVESALKRFYGVKDSGKILPGHG
GILDRFDSLLFVLPLLHILQII

Sequences:

>Translated_262_residues
MKTRIITAVVALIFFIPFVVYGGIPFELLSILLATIALYEVLVMTKQRIFSMNGIITLLLMWLVVVPDRYLDFLDTLHIT
EMEVIFILMALLLANTVFSRNKFHFDQVGICMVAAFYTGFGFHYLALTREAGLMYVLFALFIVWSTDTGAYFIGKAIGKH
KLAPNVSPNKTVEGFIGGIVCALVIAGGFYYFAELPGNIALVLALLVFLSIFGQLGDLVESALKRFYGVKDSGKILPGHG
GILDRFDSLLFVLPLLHILQII
>Mature_262_residues
MKTRIITAVVALIFFIPFVVYGGIPFELLSILLATIALYEVLVMTKQRIFSMNGIITLLLMWLVVVPDRYLDFLDTLHIT
EMEVIFILMALLLANTVFSRNKFHFDQVGICMVAAFYTGFGFHYLALTREAGLMYVLFALFIVWSTDTGAYFIGKAIGKH
KLAPNVSPNKTVEGFIGGIVCALVIAGGFYYFAELPGNIALVLALLVFLSIFGQLGDLVESALKRFYGVKDSGKILPGHG
GILDRFDSLLFVLPLLHILQII

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=155, Percent_Identity=42.5806451612903, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787677, Length=111, Percent_Identity=46.8468468468468, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29070; Mature: 29070

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS01315 CDS ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA