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The map label for this gene is inlI [H]

Identifier: 226223892

GI number: 226223892

Start: 1300273

End: 1302093

Strand: Direct

Name: inlI [H]

Synonym: Lm4b_01299

Alternate gene names: 226223892

Gene position: 1300273-1302093 (Clockwise)

Preceding gene: 226223891

Following gene: 226223894

Centisome position: 44.64

GC content: 35.58

Gene sequence:

>1821_bases
ATGTCAGTAAAATCAAATATCGTAAAAATTGGGGTATGCTTTGCAGTACTCGCTGTCCCCGTATCGCAAACAACATTCCC
GGTATTTGCTGCAGAGCAAACTGGATTAAAAGCAAGTCAGGATAATGTGAACATTCCAGATTCAACATTTAAAGCGTACT
TAAATGGATTATTAGGACAATCGAGTACAGCGAATATTACTGAAGCACAAATGAATTCATTAACATATATTACTTTAGCG
AATATAAATGTTACTGATCTAACAGGTATTGAATATGCTCATAATATAAAAGATTTAACCATAAATAATATTCATGCAAC
AAACTATAATCCAATAAGCGGGTTGAGTAATCTTGAACGATTAAGAATTATGGGAAAAGATGTTACATCCGATAAAATTC
CAAATTTAAGTGGGCTGACGAGTTTAACTCTACTGGATATTTCGCACAGTGCACATGATGATTCTATTTTAACTAAAATA
AACACACTTCCTAAAGTAAATAGTATTGACCTTAGTTATAATGGTGCAATAACGGATATCATGCTACTTAAAACATTGCC
AGAACTTAAGAGCTTAAATATTCAATTTGACGGAGTACATGATTATCGAGGTATAGAAGATTTCCCTAAATTGAATCAAC
TGTATGCATTTTCCCAAACTATAGGGGGTAAAAAACTAATTAACTCCGATATTAAAGGTAGTGCATTAACTTATAATGCA
GAAAAGCAAACATTATACGTCCCATTCAGCTTGATGACGGAACGAACAGTTAATTATGATGGCTATGTACCAGATTTCGT
AAAATCAACTGCAGGCAGCGACACTTACTTTGCAATGAATGAGAAACAAGTAAATGGCAATCGCCTAACAATTACGAGTG
ATGGCTTAACAGTAAGTGATGTAAGTAAAGCAGATTTTGATAATCTTGAAAAAATGGAGTACAACGCGAAAATCGATTTG
AGTTCTCAAACTTATAATATTCCTGATCAGTTTAAAAATGGTGGGGCGTACAATATATCTGTACCTATCTATGATCATTA
CTTCACTGTCGACCATTCTGTAAACATCTCAGCTGACAGTGGAAAAACATATATAGAAAATCAACCAGTGACAGAAGCAG
AATTTTTAGCAGATATTCATGCAAAAACAGATGACGGATCAACTGTTACAAGTGATTTCGCTGATAAAGTAGATTTCAAG
ACTCCTGGAACGTACACAGTTACTTTACAATCTGAGAATAATTCTGGATTAAAGGCAGCCCCAGTTCAAGTAAACGTAAC
AATTAAAGAGAAGACAGCGATTACGGCAGATGAAAAAATCACTTATAAGGTGGATACATCTAAAACAGAAGCAGAATTTT
TAGCAGACATCAAAGCGAAAACAAATGATGGAACAGCGATTACAAGTGATTTTGCGACTGTTGTTGATCTTTCCAAACCA
GGAAAATATGTCGTTACACTAAACGCAGAAAATGATTTACAAAAAGCTTTGCCAGTGCAAGTGACGGTTATTGTTGAAAA
AGAAACACCAATACCAGACCCAACGCCAAATCCAACACCAGATCCGACGCCAAATCCAACACCAACACCAGATCCAACAC
CGGACCCAAGCCCAACACCTAATCCGGTTATCAAACCAAACGTCAATAAACCAGAAGTGCCAAGTCACAAAATTCCATCT
TTAACTGTAAATGAGAAAAAAGCTAAAGCAGAAACAAGCAAAGAGGCTTTACCTAAAACAGGGGATTCCTTGCCTGTAGC
AGGTGCAACAGTAGGATTTTTACTAATTAGCTTAAGCTGGTTTGTTTCTAGGAAAAAATAA

Upstream 100 bases:

>100_bases
CATATGCTGAGGAGACTATAATTACATCATAAAGTTTCTTTTAAGGATACCTCTTAAAATTTACTAGGCGAATATAACAG
AGTGGAGATGGTAATAACTT

Downstream 100 bases:

>100_bases
AAATAACTATCCGCCCAATTAAGGGCGGATAGTTATTTATTCATGACGCTAGTTAACATGGCGACATAAGCTTGAGCACC
AGATTTAGTTAAATGAACAC

Product: internalin like protein (LPXTG motif)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MSVKSNIVKIGVCFAVLAVPVSQTTFPVFAAEQTGLKASQDNVNIPDSTFKAYLNGLLGQSSTANITEAQMNSLTYITLA
NINVTDLTGIEYAHNIKDLTINNIHATNYNPISGLSNLERLRIMGKDVTSDKIPNLSGLTSLTLLDISHSAHDDSILTKI
NTLPKVNSIDLSYNGAITDIMLLKTLPELKSLNIQFDGVHDYRGIEDFPKLNQLYAFSQTIGGKKLINSDIKGSALTYNA
EKQTLYVPFSLMTERTVNYDGYVPDFVKSTAGSDTYFAMNEKQVNGNRLTITSDGLTVSDVSKADFDNLEKMEYNAKIDL
SSQTYNIPDQFKNGGAYNISVPIYDHYFTVDHSVNISADSGKTYIENQPVTEAEFLADIHAKTDDGSTVTSDFADKVDFK
TPGTYTVTLQSENNSGLKAAPVQVNVTIKEKTAITADEKITYKVDTSKTEAEFLADIKAKTNDGTAITSDFATVVDLSKP
GKYVVTLNAENDLQKALPVQVTVIVEKETPIPDPTPNPTPDPTPNPTPTPDPTPDPSPTPNPVIKPNVNKPEVPSHKIPS
LTVNEKKAKAETSKEALPKTGDSLPVAGATVGFLLISLSWFVSRKK

Sequences:

>Translated_606_residues
MSVKSNIVKIGVCFAVLAVPVSQTTFPVFAAEQTGLKASQDNVNIPDSTFKAYLNGLLGQSSTANITEAQMNSLTYITLA
NINVTDLTGIEYAHNIKDLTINNIHATNYNPISGLSNLERLRIMGKDVTSDKIPNLSGLTSLTLLDISHSAHDDSILTKI
NTLPKVNSIDLSYNGAITDIMLLKTLPELKSLNIQFDGVHDYRGIEDFPKLNQLYAFSQTIGGKKLINSDIKGSALTYNA
EKQTLYVPFSLMTERTVNYDGYVPDFVKSTAGSDTYFAMNEKQVNGNRLTITSDGLTVSDVSKADFDNLEKMEYNAKIDL
SSQTYNIPDQFKNGGAYNISVPIYDHYFTVDHSVNISADSGKTYIENQPVTEAEFLADIHAKTDDGSTVTSDFADKVDFK
TPGTYTVTLQSENNSGLKAAPVQVNVTIKEKTAITADEKITYKVDTSKTEAEFLADIKAKTNDGTAITSDFATVVDLSKP
GKYVVTLNAENDLQKALPVQVTVIVEKETPIPDPTPNPTPDPTPNPTPTPDPTPDPSPTPNPVIKPNVNKPEVPSHKIPS
LTVNEKKAKAETSKEALPKTGDSLPVAGATVGFLLISLSWFVSRKK
>Mature_605_residues
SVKSNIVKIGVCFAVLAVPVSQTTFPVFAAEQTGLKASQDNVNIPDSTFKAYLNGLLGQSSTANITEAQMNSLTYITLAN
INVTDLTGIEYAHNIKDLTINNIHATNYNPISGLSNLERLRIMGKDVTSDKIPNLSGLTSLTLLDISHSAHDDSILTKIN
TLPKVNSIDLSYNGAITDIMLLKTLPELKSLNIQFDGVHDYRGIEDFPKLNQLYAFSQTIGGKKLINSDIKGSALTYNAE
KQTLYVPFSLMTERTVNYDGYVPDFVKSTAGSDTYFAMNEKQVNGNRLTITSDGLTVSDVSKADFDNLEKMEYNAKIDLS
SQTYNIPDQFKNGGAYNISVPIYDHYFTVDHSVNISADSGKTYIENQPVTEAEFLADIHAKTDDGSTVTSDFADKVDFKT
PGTYTVTLQSENNSGLKAAPVQVNVTIKEKTAITADEKITYKVDTSKTEAEFLADIKAKTNDGTAITSDFATVVDLSKPG
KYVVTLNAENDLQKALPVQVTVIVEKETPIPDPTPNPTPDPTPNPTPTPDPTPDPSPTPNPVIKPNVNKPEVPSHKIPSL
TVNEKKAKAETSKEALPKTGDSLPVAGATVGFLLISLSWFVSRKK

Specific function: Unknown. A role in virulence could not be demonstrated [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 MucBP domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR000601
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 65790; Mature: 65658

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKSNIVKIGVCFAVLAVPVSQTTFPVFAAEQTGLKASQDNVNIPDSTFKAYLNGLLGQ
CCCCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCC
SSTANITEAQMNSLTYITLANINVTDLTGIEYAHNIKDLTINNIHATNYNPISGLSNLER
CCCCCCCHHHHCCEEEEEEECCEEEECCCCHHHCCCCEEEEEEEECCCCCCCCCHHHHHH
LRIMGKDVTSDKIPNLSGLTSLTLLDISHSAHDDSILTKINTLPKVNSIDLSYNGAITDI
HHEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHH
MLLKTLPELKSLNIQFDGVHDYRGIEDFPKLNQLYAFSQTIGGKKLINSDIKGSALTYNA
HHHHHCCHHHHCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEECC
EKQTLYVPFSLMTERTVNYDGYVPDFVKSTAGSDTYFAMNEKQVNGNRLTITSDGLTVSD
CCCEEEEEHHHEECEECCCCCCCHHHHHHCCCCCEEEEECCEECCCCEEEEEECCEEEEC
VSKADFDNLEKMEYNAKIDLSSQTYNIPDQFKNGGAYNISVPIYDHYFTVDHSVNISADS
CCCCCCCCHHHEEECEEEEECCCCCCCCHHHCCCCEEEEEEEEEEEEEEEECEEEEECCC
GKTYIENQPVTEAEFLADIHAKTDDGSTVTSDFADKVDFKTPGTYTVTLQSENNSGLKAA
CCEEECCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCEEEEEEECCCCCCCEEC
PVQVNVTIKEKTAITADEKITYKVDTSKTEAEFLADIKAKTNDGTAITSDFATVVDLSKP
CEEEEEEEECCEEEECCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEECCCEEEEECCCC
GKYVVTLNAENDLQKALPVQVTVIVEKETPIPDPTPNPTPDPTPNPTPTPDPTPDPSPTP
CCEEEEEECCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NPVIKPNVNKPEVPSHKIPSLTVNEKKAKAETSKEALPKTGDSLPVAGATVGFLLISLSW
CCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
FVSRKK
HHCCCC
>Mature Secondary Structure 
SVKSNIVKIGVCFAVLAVPVSQTTFPVFAAEQTGLKASQDNVNIPDSTFKAYLNGLLGQ
CCCCCEEEHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCC
SSTANITEAQMNSLTYITLANINVTDLTGIEYAHNIKDLTINNIHATNYNPISGLSNLER
CCCCCCCHHHHCCEEEEEEECCEEEECCCCHHHCCCCEEEEEEEECCCCCCCCCHHHHHH
LRIMGKDVTSDKIPNLSGLTSLTLLDISHSAHDDSILTKINTLPKVNSIDLSYNGAITDI
HHEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHH
MLLKTLPELKSLNIQFDGVHDYRGIEDFPKLNQLYAFSQTIGGKKLINSDIKGSALTYNA
HHHHHCCHHHHCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEECC
EKQTLYVPFSLMTERTVNYDGYVPDFVKSTAGSDTYFAMNEKQVNGNRLTITSDGLTVSD
CCCEEEEEHHHEECEECCCCCCCHHHHHHCCCCCEEEEECCEECCCCEEEEEECCEEEEC
VSKADFDNLEKMEYNAKIDLSSQTYNIPDQFKNGGAYNISVPIYDHYFTVDHSVNISADS
CCCCCCCCHHHEEECEEEEECCCCCCCCHHHCCCCEEEEEEEEEEEEEEEECEEEEECCC
GKTYIENQPVTEAEFLADIHAKTDDGSTVTSDFADKVDFKTPGTYTVTLQSENNSGLKAA
CCEEECCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHCCCCCCCEEEEEEECCCCCCCEEC
PVQVNVTIKEKTAITADEKITYKVDTSKTEAEFLADIKAKTNDGTAITSDFATVVDLSKP
CEEEEEEEECCEEEECCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEECCCEEEEECCCC
GKYVVTLNAENDLQKALPVQVTVIVEKETPIPDPTPNPTPDPTPNPTPTPDPTPDPSPTP
CCEEEEEECCCCHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NPVIKPNVNKPEVPSHKIPSLTVNEKKAKAETSKEALPKTGDSLPVAGATVGFLLISLSW
CCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
FVSRKK
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]