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The map label for this gene is luxS [H]

Identifier: 226223891

GI number: 226223891

Start: 1299178

End: 1299645

Strand: Direct

Name: luxS [H]

Synonym: Lm4b_01298

Alternate gene names: 226223891

Gene position: 1299178-1299645 (Clockwise)

Preceding gene: 226223890

Following gene: 226223892

Centisome position: 44.6

GC content: 39.74

Gene sequence:

>468_bases
ATGGCAGAAAAAATGAATGTAGAAAGTTTTAATTTGGACCATACGAAAGTAAAAGCACCTTTTGTGAGACTGGCGGGAAC
GAAAGTGGGCGTCCATGGAGATGAAATATACAAATATGATGTTCGCTTCAAACAACCTAATAAAGAACATATGGAAATGC
CAGCGCTACACTCTTTAGAACATTTGATGGCAGAACTTGCAAGAAATCATACTGACAAATTAGTAGACATTAGTCCAATG
GGATGCCAAACTGGCTTTTATGTTTCCTTCATTAATCATAGCGACTATGATGATGCACTAGAAATCATCGCCACAACACT
AACGGATGTTTTAGCTGCGACAGAAGTTCCTGCATGCAATGAAGTCCAATGCGGTTGGGCAGCAAGCCATAGTTTAGAAG
GTGCAAAAGCGCTTGCGGCGGAATTTTTAGACAAACGAGACGAATGGAAAAATGTATTTGGTGAATAA

Upstream 100 bases:

>100_bases
GATGCAAAAGATGAATAAGGAAGAAAAAGAGTTCTTGTATAGAAATATGCAAGGATTCTTTTTTTTGATATAATAACAAA
GAATAAGAGGAGGGATACGC

Downstream 100 bases:

>100_bases
AAATGAAAGCATCTATCGGAATATCGGTAGATGCTTTTTATAAATAACATATTTTTATCAAAATTAATAACGAATTTAAA
TGTCGTATGGAATACTAACG

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MAEKMNVESFNLDHTKVKAPFVRLAGTKVGVHGDEIYKYDVRFKQPNKEHMEMPALHSLEHLMAELARNHTDKLVDISPM
GCQTGFYVSFINHSDYDDALEIIATTLTDVLAATEVPACNEVQCGWAASHSLEGAKALAAEFLDKRDEWKNVFGE

Sequences:

>Translated_155_residues
MAEKMNVESFNLDHTKVKAPFVRLAGTKVGVHGDEIYKYDVRFKQPNKEHMEMPALHSLEHLMAELARNHTDKLVDISPM
GCQTGFYVSFINHSDYDDALEIIATTLTDVLAATEVPACNEVQCGWAASHSLEGAKALAAEFLDKRDEWKNVFGE
>Mature_154_residues
AEKMNVESFNLDHTKVKAPFVRLAGTKVGVHGDEIYKYDVRFKQPNKEHMEMPALHSLEHLMAELARNHTDKLVDISPMG
CQTGFYVSFINHSDYDDALEIIATTLTDVLAATEVPACNEVQCGWAASHSLEGAKALAAEFLDKRDEWKNVFGE

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=146, Percent_Identity=41.0958904109589, Blast_Score=116, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 17354; Mature: 17223

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKMNVESFNLDHTKVKAPFVRLAGTKVGVHGDEIYKYDVRFKQPNKEHMEMPALHSLE
CCCCCCCCCCCCCCHHHHCCEEEECCCEECCCCCEEEEEEEEECCCCHHHHCCCHHHHHH
HLMAELARNHTDKLVDISPMGCQTGFYVSFINHSDYDDALEIIATTLTDVLAATEVPACN
HHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EVQCGWAASHSLEGAKALAAEFLDKRDEWKNVFGE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEKMNVESFNLDHTKVKAPFVRLAGTKVGVHGDEIYKYDVRFKQPNKEHMEMPALHSLE
CCCCCCCCCCCCCHHHHCCEEEECCCEECCCCCEEEEEEEEECCCCHHHHCCCHHHHHH
HLMAELARNHTDKLVDISPMGCQTGFYVSFINHSDYDDALEIIATTLTDVLAATEVPACN
HHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EVQCGWAASHSLEGAKALAAEFLDKRDEWKNVFGE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]