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The map label for this gene is codY

Identifier: 226223883

GI number: 226223883

Start: 1290778

End: 1291557

Strand: Direct

Name: codY

Synonym: Lm4b_01290

Alternate gene names: 226223883

Gene position: 1290778-1291557 (Clockwise)

Preceding gene: 226223882

Following gene: 226223884

Centisome position: 44.32

GC content: 36.67

Gene sequence:

>780_bases
ATGACTTTATTAGAAAAAACAAGAAAAATTAATGCTATGTTACAAAATGCTGCAGGAAAAACAGTAAACTTCAAAGAAAT
GGCAGATACACTTACAGACGTCATTGAAGCAAACACATATATCGTAAGCCGTAAAGGTAAATTACTTGGCTATTCTGAAG
CACTTCCAATCGAAAATGATCGTATGAAACAAATGCTAACAGAACGCCAATTTCCAGAAGAATATACGCAAAGCCTTTTC
AATGTAGGCGAAACTTCTTCTAACTTAGAAGTATCAAGCCAATATACTGCTTTTCCAATCGAAAACAGTGAATTATTCAC
AAAAGGTTTAACAACTATCGTACCTATCGTAGGTGGTGGTGAGCGTCTTGGAACACTTATCCTATCTCGCTTAGAAAGCA
ATTTCACTGATGATGATTTACTTTTAGCGGAATATGGTGGAACAGTTGTTGGAATGGAAATCTTGCATGAAAAAGCAGAA
GAAATTGAAGAAGAAGCTCGTAGCCGTGCCGTTGTGCAAATGGCGATTAGCTCTCTTTCTTACAGTGAGTTAGAAGCTAT
TGAGCATATTTTCGATGAGTTGAATGGTAAAGAAGGTCTTCTTGTTGCCTCTAAAATCGCGGACCGTGTCGGCATTACAC
GTTCTGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCAGGCGTTATTGATTCTCGCTCACTAGGAATGAAAGGTACA
TTTATCCGTGTACTTAATGATAAATTCCTTGTAGAACTAGAAAAATTGAAAAACAACTAA

Upstream 100 bases:

>100_bases
TTAAAGTAACAGAAAACTATGTTAATGAAAAACTTGCACCAATTATGCAGAATAAAGATTTAACACAATTTATTTTATAA
AATACTAGGAGGATCTAATA

Downstream 100 bases:

>100_bases
AAAAAGTAGAAAAGCTTTCTCTGAAAATATTCGGGGAGAGCTTTTTTTGGTTTGCTTTGGTAAAATAAGAAAGTAGAACT
TGTGTGACTGGAGGAATTTA

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTLLEKTRKINAMLQNAAGKTVNFKEMADTLTDVIEANTYIVSRKGKLLGYSEALPIENDRMKQMLTERQFPEEYTQSLF
NVGETSSNLEVSSQYTAFPIENSELFTKGLTTIVPIVGGGERLGTLILSRLESNFTDDDLLLAEYGGTVVGMEILHEKAE
EIEEEARSRAVVQMAISSLSYSELEAIEHIFDELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIDSRSLGMKGT
FIRVLNDKFLVELEKLKNN

Sequences:

>Translated_259_residues
MTLLEKTRKINAMLQNAAGKTVNFKEMADTLTDVIEANTYIVSRKGKLLGYSEALPIENDRMKQMLTERQFPEEYTQSLF
NVGETSSNLEVSSQYTAFPIENSELFTKGLTTIVPIVGGGERLGTLILSRLESNFTDDDLLLAEYGGTVVGMEILHEKAE
EIEEEARSRAVVQMAISSLSYSELEAIEHIFDELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIDSRSLGMKGT
FIRVLNDKFLVELEKLKNN
>Mature_258_residues
TLLEKTRKINAMLQNAAGKTVNFKEMADTLTDVIEANTYIVSRKGKLLGYSEALPIENDRMKQMLTERQFPEEYTQSLFN
VGETSSNLEVSSQYTAFPIENSELFTKGLTTIVPIVGGGERLGTLILSRLESNFTDDDLLLAEYGGTVVGMEILHEKAEE
IEEEARSRAVVQMAISSLSYSELEAIEHIFDELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIDSRSLGMKGTF
IRVLNDKFLVELEKLKNN

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991 [H]

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY [H]

EC number: NA

Molecular weight: Translated: 28745; Mature: 28614

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLEKTRKINAMLQNAAGKTVNFKEMADTLTDVIEANTYIVSRKGKLLGYSEALPIEND
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCEECCCCCCCCCHH
RMKQMLTERQFPEEYTQSLFNVGETSSNLEVSSQYTAFPIENSELFTKGLTTIVPIVGGG
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCEECCCEEEECCCCCHHHHHHHHHHHEECCCH
ERLGTLILSRLESNFTDDDLLLAEYGGTVVGMEILHEKAEEIEEEARSRAVVQMAISSLS
HHHHHHHHHHHHCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YSELEAIEHIFDELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIDSRSLGMKGT
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
FIRVLNDKFLVELEKLKNN
HHEECCHHHHHHHHHHCCC
>Mature Secondary Structure 
TLLEKTRKINAMLQNAAGKTVNFKEMADTLTDVIEANTYIVSRKGKLLGYSEALPIEND
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCEECCCCCCCCCHH
RMKQMLTERQFPEEYTQSLFNVGETSSNLEVSSQYTAFPIENSELFTKGLTTIVPIVGGG
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCEECCCEEEECCCCCHHHHHHHHHHHEECCCH
ERLGTLILSRLESNFTDDDLLLAEYGGTVVGMEILHEKAEEIEEEARSRAVVQMAISSLS
HHHHHHHHHHHHCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YSELEAIEHIFDELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIDSRSLGMKGT
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
FIRVLNDKFLVELEKLKNN
HHEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]