| Definition | Listeria monocytogenes Clip81459, complete genome. |
|---|---|
| Accession | NC_012488 |
| Length | 2,912,690 |
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The map label for this gene is mtlR [H]
Identifier: 226223126
GI number: 226223126
Start: 533058
End: 535118
Strand: Direct
Name: mtlR [H]
Synonym: Lm4b_00523
Alternate gene names: 226223126
Gene position: 533058-535118 (Clockwise)
Preceding gene: 226223125
Following gene: 226223127
Centisome position: 18.3
GC content: 36.34
Gene sequence:
>2061_bases ATGTATCTGGATAACAGAAGTAAAACACTATTTCAAGAAGTTATAAAAAATCCGAACATTACAAATAAACAACTCGAAGT AAAGTATAAATTATCGCGTTACCAAATCAGCTATAGTTTTCAGAAAGTAAACGAATGGCTCAAGTGGAAAAATTATCCAG AAGTAAAGCGTTCCAAAAACGGCCGATTTATATTAGAACCCGAGCTTACAGCGCTATTTTCTGAGAAAGAAACTCGAGAT CCGAGCGTAGAATACTTACCTTCTGAAAATGAACGTGCCAATTTAATTTTGCTAATGCTTTTAACAGCCAAAGAAGAACT ATCCCTCGCCCATTTTACAACGAAGATTCAAGTAAGCAAAAACACCATTCTTCGTGATTTAAAAGTAGCGCAAAAATTAC TTCCTAAAGAAACAACTGTCACTTATAGTAGAGCATCGGGTTATCAGTTAGCAGGGAGTGAATGGGAACTTCGCAAGGTT CTGACACAAGTTGTAAGTAGTGTGAAAGAGATGTTCCGAGGAGAGCACTATTTCCTATCGTATTCAGGAATTGAAAAAGT CCAACTAATGGAAATTCGCCGCACACTCGAAGAAGCAGAAGCGATGATGCAAATAAAATTCACCTATGAGCAAATCGAAT TATTACCCTATTTGCTATCCGTGATGTTCTTAAGAATCAGAGACCGGCGCTTAATCGACACTGCTTTTCATATTGACGAG AAATCACTTTCAGACACGCGAGAATACCACATCACCGATATTTTGCTCGAAAAAACTGGCCCAGTTCCAGAACAAGAGCG ACTTTTCATCACATTACAACTTCTTACAACAAACATTTTTTCCGGCGAAATTTTAACTGAAAAATTAACAGAAGACTTGG AAAAAGTTGTCCTCACATGCTTAGACTTATTCGAGAAAAAAGCACTTGTTTCTCTTAAAAACAAACATATCTTAATCGAA AAATTACTCTTACATTTAAAACCAGCCTATTACCGGATTAAATACCAAATGAATTTAGAAGATACGCTTTATGAAAAATT CAACCAAGAATTCGAAGCGTTAAACTTCATTGTGAAAGAAGCATTTGACCCACTTGCGAAATTTATTGGTCGCGAAATTC CAGCCGGCGAAATTTTCTTCATTTCTTTGTTTATTGGGAGCGACATGATACCGCAAAACGATATTTATCATAAACAAAAA CGTGCGATTGTGCTTTGTCCGAGCGGGGTTACTTTTTCAAAAATCATGGAAAATATTTTAGTGAAACTATTCCCGGAAAT CCATTTTTATCCAACTATATCTGTTCGGGAATATGCCTTTTTTAAAGCAGAAGTTGATATTGTTTTTTCATCCATTCCGT TAAAAGATGGCGAAAATGTCTTTGTTGTTCAGCCATTTATGAATGATATCGAAAAAACGCAACTGCGGCAACACGTCTTG CAAAATTTATTTGGAATGGGAAACCAGCTCACGAGTATTGATAAAATCATGGAAGTAGTGGAACGTAACGCCGATATAAA GGATCCGAATGCAATACGAGATGGAATTATTGATATTTTGTCGGCTAACACAGCTACAGATGAAAATAAACGCGTGAAAA AAGTCTATTTACATGATTTAATCACCGAAGATAACATCATGATTTGTGAGGATGTTAAAAACTATCAAGAAGCGATTCGT CTAGCAAGTCAGCCGCTGTTACTACAACAAGCAATTACAGCAAACTATGTAAAGACCATGATTGATAACCATAAGTTCCA CGATCCGTACATTATTATCGGTGAAGATATTGCCATTCCACACGCTATGCCTAATGCGGGGGTGAATCGACTCGCTATGT CTCTTTTAGTCGTGAAAAATGGCGTATATTTTTCAGAAACAGAGCAAGTTCATTTCGTAATAGTTATCGCACCAGTGGAT AAAGAGCAACACATTGAAGCACTTTACCAAATCGTTCATTTAGCCGAAAATCACCAAATTTTAGACGATTTGCTCGAAAA TGTAACCAAAGAAAAAGTCATGCAAACTATCAACCAATTAGTAATTAGAGAGGATGAATAA
Upstream 100 bases:
>100_bases TTCTCATGTTGTGGAAGTGTGTGGAGAAAACTTGTGATGAAAGCGCATTCTTAAGCGCCAAACCCTATGCTATAATTAGG CTATCAAAGGGGGGAGACGC
Downstream 100 bases:
>100_bases ATTTTGGATAAACAAGCTATTTTAGATAATATTCACCAAACATGGCAAGAAGAAGCAAACGCGATTTCCCGTTTGCCGGA AGTAACAAGTGAAGAGGCTC
Product: transcription antiterminator (BglG family)
Products: NA
Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 686; Mature: 686
Protein sequence:
>686_residues MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRD PSVEYLPSENERANLILLMLLTAKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKV LTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDE KSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIE KLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQK RAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVL QNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIR LASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVD KEQHIEALYQIVHLAENHQILDDLLENVTKEKVMQTINQLVIREDE
Sequences:
>Translated_686_residues MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRD PSVEYLPSENERANLILLMLLTAKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKV LTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDE KSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIE KLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQK RAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVL QNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIR LASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVD KEQHIEALYQIVHLAENHQILDDLLENVTKEKVMQTINQLVIREDE >Mature_686_residues MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRD PSVEYLPSENERANLILLMLLTAKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKV LTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDE KSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIE KLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQK RAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVL QNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIR LASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVD KEQHIEALYQIVHLAENHQILDDLLENVTKEKVMQTINQLVIREDE
Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
Organism=Escherichia coli, GI1789302, Length=113, Percent_Identity=32.7433628318584, Blast_Score=72, Evalue=1e-13, Organism=Escherichia coli, GI2367359, Length=147, Percent_Identity=27.2108843537415, Blast_Score=65, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 79845; Mature: 79845
Theoretical pI: Translated: 5.89; Mature: 5.89
Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKN CCCCCCHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHCCCCCHHHHCCC GRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTAKEELSLAHFTTKIQVSK CCEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHEEEEEEECH NTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLS HHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEE YSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDE ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC KSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTC HHHCCCHHHHHHHEEEECCCCCCCCCEEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHH LDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKE HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHH AFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENIL HHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCHHCCCCEEEECCCCCCHHHHHHHHH VKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVL HHHCCCCEEEECCCHHHHEEEEEEEEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHH QNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDL HHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH ITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIP HCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEECC HAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQI CCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEEEEEECCHHHHHHHHHHHHHHHCCHHH LDDLLENVTKEKVMQTINQLVIREDE HHHHHHHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKN CCCCCCHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHCCCCCHHHHCCC GRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTAKEELSLAHFTTKIQVSK CCEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHEEEEEEECH NTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLS HHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEE YSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDE ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC KSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTC HHHCCCHHHHHHHEEEECCCCCCCCCEEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHH LDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKE HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHH AFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENIL HHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCHHCCCCEEEECCCCCCHHHHHHHHH VKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVL HHHCCCCEEEECCCHHHHEEEEEEEEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHH QNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANTATDENKRVKKVYLHDL HHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH ITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIP HCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEECC HAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQI CCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEEEEEECCHHHHHHHHHHHHHHHCCHHH LDDLLENVTKEKVMQTINQLVIREDE HHHHHHHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]