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The map label for this gene is gmuR [H]

Identifier: 226222998

GI number: 226222998

Start: 399288

End: 400001

Strand: Reverse

Name: gmuR [H]

Synonym: Lm4b_00390

Alternate gene names: 226222998

Gene position: 400001-399288 (Counterclockwise)

Preceding gene: 226223003

Following gene: 226222990

Centisome position: 13.73

GC content: 39.08

Gene sequence:

>714_bases
ATGTCGGGAATGGCTAAATACATGGAAATATACATAGATATCCGTGATAAAATCAACCAAAACAAATACGAAATTAACGA
GAAATTGCCTGATGGGGACAGTATGGCTCGCACGTATGATTGCAGCAAGCTCACTGTCAAAAAAGCACTGGATATGCTTG
TACAAGAAGGCATGATTATTAGACGACGCGGGGCTGGGACTTTCGTGAAATCCCATTCGACTAACGGCGGCGAATTCGCG
CTTGGGCCAATGTCCGGACTTGTAAATACATTTGGAAAAGACAATATTAAATCCAAAGTCATTTTATTTTCTATTGAAAA
ACCATCGAAAGAAGTTGCAGAAAAATTAGAAATGAAGGATGATTACATTTACCGAATTATTCGGATGAGGGAAGTTGGTC
ATAAAGCCTATTCCATCGAACATACTTATATGCCACTTGCGATTATTCCGGGTCTAGAACCACGTCATTTAGAGGACTCG
ATTTATAATTATATTCGGGATGATTTGAAACTTAAGATGCAGAGTGCGCATGTTTGGGTACGCGGGGATAAATCAAATCA
AGAGGATAGCAAGCTCCTCGATTTAGAAGAACCTACTTTTATGATGGAAATTGAAAAATTAGCGCATTTGGAAGATGGTC
GTGTGTTCGAATATTCGATAACGCGCCATACGTATGAATCGTTTGTGTTTGAAACGGTTTTTGTGCAGAATTAA

Upstream 100 bases:

>100_bases
ATACTTTTATTAAAAGATATATACTTTTGTTTATAGGGATACCTTTTTGTAAAAGTATATGGTATACTATGCTTATTACA
TCAGTAAAGGAGCCAATAAA

Downstream 100 bases:

>100_bases
AAAAAACAGCGACTCTCTACTAAGAGAATCGCTGTTTTTTATATCTTCTTAACAAATTCTGATTTTAATTTCATTGGGCC
GAAGCCGTCAATTTTGCAAT

Product: transcription regulator (GntR family)

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSGMAKYMEIYIDIRDKINQNKYEINEKLPDGDSMARTYDCSKLTVKKALDMLVQEGMIIRRRGAGTFVKSHSTNGGEFA
LGPMSGLVNTFGKDNIKSKVILFSIEKPSKEVAEKLEMKDDYIYRIIRMREVGHKAYSIEHTYMPLAIIPGLEPRHLEDS
IYNYIRDDLKLKMQSAHVWVRGDKSNQEDSKLLDLEEPTFMMEIEKLAHLEDGRVFEYSITRHTYESFVFETVFVQN

Sequences:

>Translated_237_residues
MSGMAKYMEIYIDIRDKINQNKYEINEKLPDGDSMARTYDCSKLTVKKALDMLVQEGMIIRRRGAGTFVKSHSTNGGEFA
LGPMSGLVNTFGKDNIKSKVILFSIEKPSKEVAEKLEMKDDYIYRIIRMREVGHKAYSIEHTYMPLAIIPGLEPRHLEDS
IYNYIRDDLKLKMQSAHVWVRGDKSNQEDSKLLDLEEPTFMMEIEKLAHLEDGRVFEYSITRHTYESFVFETVFVQN
>Mature_236_residues
SGMAKYMEIYIDIRDKINQNKYEINEKLPDGDSMARTYDCSKLTVKKALDMLVQEGMIIRRRGAGTFVKSHSTNGGEFAL
GPMSGLVNTFGKDNIKSKVILFSIEKPSKEVAEKLEMKDDYIYRIIRMREVGHKAYSIEHTYMPLAIIPGLEPRHLEDSI
YNYIRDDLKLKMQSAHVWVRGDKSNQEDSKLLDLEEPTFMMEIEKLAHLEDGRVFEYSITRHTYESFVFETVFVQN

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790118, Length=221, Percent_Identity=25.7918552036199, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786950, Length=214, Percent_Identity=27.1028037383178, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27510; Mature: 27379

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGMAKYMEIYIDIRDKINQNKYEINEKLPDGDSMARTYDCSKLTVKKALDMLVQEGMII
CCCHHEEHHEEEEEHHCCCCCCEECCCCCCCCCCHHEECCCHHHHHHHHHHHHHHCCEEE
RRRGAGTFVKSHSTNGGEFALGPMSGLVNTFGKDNIKSKVILFSIEKPSKEVAEKLEMKD
EECCCCCEEECCCCCCCCEEECHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHCCCH
DYIYRIIRMREVGHKAYSIEHTYMPLAIIPGLEPRHLEDSIYNYIRDDLKLKMQSAHVWV
HHHHHHHHHHHHCCCEEEEECCEECEEEECCCCCCHHHHHHHHHHHHHHHEEEEEEEEEE
RGDKSNQEDSKLLDLEEPTFMMEIEKLAHLEDGRVFEYSITRHTYESFVFETVFVQN
ECCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
SGMAKYMEIYIDIRDKINQNKYEINEKLPDGDSMARTYDCSKLTVKKALDMLVQEGMII
CCHHEEHHEEEEEHHCCCCCCEECCCCCCCCCCHHEECCCHHHHHHHHHHHHHHCCEEE
RRRGAGTFVKSHSTNGGEFALGPMSGLVNTFGKDNIKSKVILFSIEKPSKEVAEKLEMKD
EECCCCCEEECCCCCCCCEEECHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHCCCH
DYIYRIIRMREVGHKAYSIEHTYMPLAIIPGLEPRHLEDSIYNYIRDDLKLKMQSAHVWV
HHHHHHHHHHHHCCCEEEEECCEECEEEECCCCCCHHHHHHHHHHHHHHHEEEEEEEEEE
RGDKSNQEDSKLLDLEEPTFMMEIEKLAHLEDGRVFEYSITRHTYESFVFETVFVQN
ECCCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]