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The map label for this gene is dhaK [H]

Identifier: 226222974

GI number: 226222974

Start: 376586

End: 377581

Strand: Reverse

Name: dhaK [H]

Synonym: Lm4b_00366

Alternate gene names: 226222974

Gene position: 377581-376586 (Counterclockwise)

Preceding gene: 226222975

Following gene: 226222973

Centisome position: 12.96

GC content: 42.07

Gene sequence:

>996_bases
ATGAGACGTTTAGTGAATGATGGGTATGAAGCAGTAGAAGAAATGTTAGCTGGTTATGTTGCGGCACAAGGGAAATACGT
AGATTTTGCAGAAAATGATAAGCGAGTAATCGTAAGCAAACAAATGAGCGAAGAACCTCGTGTGCGAATTATTGTTGGTG
GCGGTTCTGGTCATGAACCACTTTTCCTTGGTTATGTTGGGAAAGATTTCGCGGATGCGGCGGTAGTTGGGAACATTAAT
ACTTCCCCTTCTCCAGAACCTTGTTATAACGCAGTAAAAGCCGTTGATAGCGGTAAAGGTTGTCTATATATGTACGGAAA
TTATGCTGGCGATGTGATGAACTTTGATATGGGCGCTGAAATGGCTGCGGACGACGGTATTCGCGTTGAAACAGTGCTTG
TAACAGATGATATTTACTCTGCTGAAAATGTAGAAGATCGTCGTGGTGTGGCTGGTGACTTAATTGTATTTAAAGCAGCG
GCATCTGCAGCAGCAAAAGGACTTGACCTAGATGCGGTGAAACAAGCTGCTGAAAAAGCTAATGCAAATACGTTCTCGAT
GGGTGTTGCGCTTTCTTCTTCTACCCTTCCTGTAACTGGTAAAGCTATTTTCGAAATGAAAGAAGGCGAAATGGAAGTTG
GTATGGGAATCCACGGTGAACCAGGAATCAAACGCACTTCCATCGAACCAGCTGATAAAGTGGTTGATCAAATTATGGGC
TATCTTATAGAAGAAATGAAATTAACTGCGGATGAAGAAGTGCATGTACTTATTAATGGACTTGGCGGTTTACCAGTGAT
GGATCAATATATTTGTTATCGCCGCGTCGATGAAATTTTGAAAGAAAAAGGCGTGCATATTCATAACCCACTTGTTGGGA
ACTACGCGACTTCGATGGATATGATTGGTATGTCGATTACACTGGTTCGTTTAGACGATGAACTGAAAGATCTTTTAGAT
ACACCGTGCGACACACCATATTTCAAAGTGGACTAA

Upstream 100 bases:

>100_bases
TTCTAAATCGATAGTCAATTTGGCAGCAGCTGTAGTTGGTGGCGTGGTTGGCGGATTTTTACTATCACTATTCTTATAAA
AATATGAAGGAGGAAGAAAA

Downstream 100 bases:

>100_bases
ATTACTACTGGAGGAATAAAAATGAGCGAATTAGTTATGGATAGCGCTTTTTTCGGCCACGTTTTACAGGACATGGGAGC
GCTAATTGAAAAAGAACGTG

Product: dihydroxyacetone kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRRLVNDGYEAVEEMLAGYVAAQGKYVDFAENDKRVIVSKQMSEEPRVRIIVGGGSGHEPLFLGYVGKDFADAAVVGNIN
TSPSPEPCYNAVKAVDSGKGCLYMYGNYAGDVMNFDMGAEMAADDGIRVETVLVTDDIYSAENVEDRRGVAGDLIVFKAA
ASAAAKGLDLDAVKQAAEKANANTFSMGVALSSSTLPVTGKAIFEMKEGEMEVGMGIHGEPGIKRTSIEPADKVVDQIMG
YLIEEMKLTADEEVHVLINGLGGLPVMDQYICYRRVDEILKEKGVHIHNPLVGNYATSMDMIGMSITLVRLDDELKDLLD
TPCDTPYFKVD

Sequences:

>Translated_331_residues
MRRLVNDGYEAVEEMLAGYVAAQGKYVDFAENDKRVIVSKQMSEEPRVRIIVGGGSGHEPLFLGYVGKDFADAAVVGNIN
TSPSPEPCYNAVKAVDSGKGCLYMYGNYAGDVMNFDMGAEMAADDGIRVETVLVTDDIYSAENVEDRRGVAGDLIVFKAA
ASAAAKGLDLDAVKQAAEKANANTFSMGVALSSSTLPVTGKAIFEMKEGEMEVGMGIHGEPGIKRTSIEPADKVVDQIMG
YLIEEMKLTADEEVHVLINGLGGLPVMDQYICYRRVDEILKEKGVHIHNPLVGNYATSMDMIGMSITLVRLDDELKDLLD
TPCDTPYFKVD
>Mature_331_residues
MRRLVNDGYEAVEEMLAGYVAAQGKYVDFAENDKRVIVSKQMSEEPRVRIIVGGGSGHEPLFLGYVGKDFADAAVVGNIN
TSPSPEPCYNAVKAVDSGKGCLYMYGNYAGDVMNFDMGAEMAADDGIRVETVLVTDDIYSAENVEDRRGVAGDLIVFKAA
ASAAAKGLDLDAVKQAAEKANANTFSMGVALSSSTLPVTGKAIFEMKEGEMEVGMGIHGEPGIKRTSIEPADKVVDQIMG
YLIEEMKLTADEEVHVLINGLGGLPVMDQYICYRRVDEILKEKGVHIHNPLVGNYATSMDMIGMSITLVRLDDELKDLLD
TPCDTPYFKVD

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=327, Percent_Identity=30.8868501529052, Blast_Score=162, Evalue=4e-40,
Organism=Escherichia coli, GI87081857, Length=352, Percent_Identity=34.6590909090909, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17565018, Length=329, Percent_Identity=32.2188449848024, Blast_Score=177, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6321055, Length=296, Percent_Identity=32.4324324324324, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6323570, Length=306, Percent_Identity=31.3725490196078, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: NA

Molecular weight: Translated: 35787; Mature: 35787

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLVNDGYEAVEEMLAGYVAAQGKYVDFAENDKRVIVSKQMSEEPRVRIIVGGGSGHEP
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCC
LFLGYVGKDFADAAVVGNINTSPSPEPCYNAVKAVDSGKGCLYMYGNYAGDVMNFDMGAE
EEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCC
MAADDGIRVETVLVTDDIYSAENVEDRRGVAGDLIVFKAAASAAAKGLDLDAVKQAAEKA
CCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHC
NANTFSMGVALSSSTLPVTGKAIFEMKEGEMEVGMGIHGEPGIKRTSIEPADKVVDQIMG
CCCEEEEEEEECCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
YLIEEMKLTADEEVHVLINGLGGLPVMDQYICYRRVDEILKEKGVHIHNPLVGNYATSMD
HHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHH
MIGMSITLVRLDDELKDLLDTPCDTPYFKVD
HCCEEEEEEEECHHHHHHHCCCCCCCCEECC
>Mature Secondary Structure
MRRLVNDGYEAVEEMLAGYVAAQGKYVDFAENDKRVIVSKQMSEEPRVRIIVGGGSGHEP
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCCCEEEEEECCCCCCC
LFLGYVGKDFADAAVVGNINTSPSPEPCYNAVKAVDSGKGCLYMYGNYAGDVMNFDMGAE
EEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCCCC
MAADDGIRVETVLVTDDIYSAENVEDRRGVAGDLIVFKAAASAAAKGLDLDAVKQAAEKA
CCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHC
NANTFSMGVALSSSTLPVTGKAIFEMKEGEMEVGMGIHGEPGIKRTSIEPADKVVDQIMG
CCCEEEEEEEECCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
YLIEEMKLTADEEVHVLINGLGGLPVMDQYICYRRVDEILKEKGVHIHNPLVGNYATSMD
HHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHH
MIGMSITLVRLDDELKDLLDTPCDTPYFKVD
HCCEEEEEEEECHHHHHHHCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]