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The map label for this gene is dhaL [H]

Identifier: 226222973

GI number: 226222973

Start: 375914

End: 376564

Strand: Reverse

Name: dhaL [H]

Synonym: Lm4b_00365

Alternate gene names: 226222973

Gene position: 376564-375914 (Counterclockwise)

Preceding gene: 226222974

Following gene: 226222972

Centisome position: 12.93

GC content: 45.01

Gene sequence:

>651_bases
ATGAGCGAATTAGTTATGGATAGCGCTTTTTTCGGCCACGTTTTACAGGACATGGGAGCGCTAATTGAAAAAGAACGTGA
TTACTTAACCGGACTGGACTCGGATATTGGAGACGGCGACCACGGAATCAATCTTAGTATTGGCTTTCGTGAAGTGAATA
AACAATTAGACGAATTACTCACTGCTTCTCCCGATATTGCAACGTTGCTTAAAAAATCCGGAATGATTCTCCTTGGAAAA
GTTGGTGGCGCATCTGGCCCGCTTTATGGCAGTTTCTTTATGAAATGTGGCGCTGATGTTCCTGGGAAAACGGAGGTTAA
CTTCGACGAGCTTTGCGGCATGATTATAAATGGGGCCGCTGCGGTTCAACATCGCGGAAAAGCCGAACTTGGTGATAAAA
CGATGATGGACGCCTTCTTGCCTGGCGTGGAAGTGCTTCAAAATCGAGATACAAATGCAGCTCCAATCGAAACTTTTTCC
GCATTTGTAGATGCTATGCATGCTGGCGCTCAGTCCACTATCCCACTTATTGCTAAGAAAGGTCGCGCACTAAGACTTGG
CGAACGAGCAATTGGTCACCTTGATCCTGGCTCTGAATCGTCTTGGATGTTAATGAATGTCATTTTAGAAAATTTAAAAA
AGGCGGTCTGA

Upstream 100 bases:

>100_bases
TACACTGGTTCGTTTAGACGATGAACTGAAAGATCTTTTAGATACACCGTGCGACACACCATATTTCAAAGTGGACTAAA
TTACTACTGGAGGAATAAAA

Downstream 100 bases:

>100_bases
TTTATGCGTAAACCCTTAGTTGGAATTAATATGAAAAACTATATTAACACTCGGGCTCAGACATCTGAATGGTTAGAAGC
GACTATCCCTCTTCTTAAAA

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSELVMDSAFFGHVLQDMGALIEKERDYLTGLDSDIGDGDHGINLSIGFREVNKQLDELLTASPDIATLLKKSGMILLGK
VGGASGPLYGSFFMKCGADVPGKTEVNFDELCGMIINGAAAVQHRGKAELGDKTMMDAFLPGVEVLQNRDTNAAPIETFS
AFVDAMHAGAQSTIPLIAKKGRALRLGERAIGHLDPGSESSWMLMNVILENLKKAV

Sequences:

>Translated_216_residues
MSELVMDSAFFGHVLQDMGALIEKERDYLTGLDSDIGDGDHGINLSIGFREVNKQLDELLTASPDIATLLKKSGMILLGK
VGGASGPLYGSFFMKCGADVPGKTEVNFDELCGMIINGAAAVQHRGKAELGDKTMMDAFLPGVEVLQNRDTNAAPIETFS
AFVDAMHAGAQSTIPLIAKKGRALRLGERAIGHLDPGSESSWMLMNVILENLKKAV
>Mature_215_residues
SELVMDSAFFGHVLQDMGALIEKERDYLTGLDSDIGDGDHGINLSIGFREVNKQLDELLTASPDIATLLKKSGMILLGKV
GGASGPLYGSFFMKCGADVPGKTEVNFDELCGMIINGAAAVQHRGKAELGDKTMMDAFLPGVEVLQNRDTNAAPIETFSA
FVDAMHAGAQSTIPLIAKKGRALRLGERAIGHLDPGSESSWMLMNVILENLKKAV

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Escherichia coli, GI1787449, Length=195, Percent_Identity=44.1025641025641, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 23053; Mature: 22922

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELVMDSAFFGHVLQDMGALIEKERDYLTGLDSDIGDGDHGINLSIGFREVNKQLDELL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHH
TASPDIATLLKKSGMILLGKVGGASGPLYGSFFMKCGADVPGKTEVNFDELCGMIINGAA
HCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHH
AVQHRGKAELGDKTMMDAFLPGVEVLQNRDTNAAPIETFSAFVDAMHAGAQSTIPLIAKK
HHHHCCCCCCCHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCC
GRALRLGERAIGHLDPGSESSWMLMNVILENLKKAV
CCEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SELVMDSAFFGHVLQDMGALIEKERDYLTGLDSDIGDGDHGINLSIGFREVNKQLDELL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHH
TASPDIATLLKKSGMILLGKVGGASGPLYGSFFMKCGADVPGKTEVNFDELCGMIINGAA
HCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHH
AVQHRGKAELGDKTMMDAFLPGVEVLQNRDTNAAPIETFSAFVDAMHAGAQSTIPLIAKK
HHHHCCCCCCCHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCC
GRALRLGERAIGHLDPGSESSWMLMNVILENLKKAV
CCEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]