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The map label for this gene is inlA [H]

Identifier: 226222905

GI number: 226222905

Start: 299847

End: 300932

Strand: Reverse

Name: inlA [H]

Synonym: Lm4b_00297

Alternate gene names: 226222905

Gene position: 300932-299847 (Counterclockwise)

Preceding gene: 226222906

Following gene: 226222839

Centisome position: 10.33

GC content: 34.44

Gene sequence:

>1086_bases
ATGAAAAAATTTATTCTAGCAAGCCTTGCATGTACGACTTTGATTAGTTTTAGTCCTTTGGTAGGACAAGTCGAAGTAAG
CGCTGCTACAACAAACATTGCCACTGCCCCAGAAAAAAATTTACAAGAAGCTCCTCCAGCCACGGTTGATCAAATTTTCC
CAGATGATGCTCTAGCTTTTAAAGTCGCACAGGAACTAGGTGTTTCCGAGGATACAGTCGTTACACAAGAACAACTAGAT
ACTATCGAAACAATGGTATATGTGGATTTCGGTGTGGAAGATTTAACAGGCATGGAATATTTACACAACTTAAAATTTGT
AGATTTAAGCCAAAATAAAATTAGCAACTTAGAGAATCTCGCTAATTTAACAGAATTAGAAACGGTATCACTTAACTACA
ATCAAATTACAGATATTACTCCACTAATGAACTCACCTAAATTATATAACTTAGAATTAGGCGTTAACCAAATCTCTACT
TTACCATCCTTCGAAAATTTAACTAATTTAAGGATATTAAATCTAAGTAGCAATCAACTAAAAGATATTTCGGCCCTAAA
AGATACTCCTCAATTAACTAATTTATCTATTTCAGCAAATAATATATCAGACATCAGTGTCCTTTCAGAATGCGATAATC
TCCGAGTTTTTTATGCCGAAAGCAATCAACTGACTTCTATTGAGTCATTAAGAAATAAAACAAAACTAGAATACTTCGAT
GCTAATTTTAATCAAATTAAAGATGTTACACCTCTCAGTACCATTCCAACAATTAGGTCAATAAAAATTGAAGAAAATCA
GATTAGTGATTTCAGCTCATTGGCAGGTCACCGCTTAGAATTGTTTGATGCTACTGGACAAAATATATACCTTCCAGATG
TTGCGCTCGGCGATTCCACTAATATTGTAATGAAAGATAATCTCGGAGTAACATTACATGATTGGGTTTGGTACACCCCA
GGAACTTACCAAAATGATACACTTACTTGGGAAAATGCAGGCGATAATTCCGCTTACTTTTTAAATAATCAATATCCAAC
TTACCCTTCTGTCACAGTGACTGTCTATCAAACAGTCACTCCTTAA

Upstream 100 bases:

>100_bases
TAGCGGTTTTTTTATGCAATGTTCATATGTGATGGCTTTTTATTTTTAAATAATTTGCATGCTATACTCCATTTATATTA
TAGAAAAGGAGTAGGATGAC

Downstream 100 bases:

>100_bases
ATAATAATAGCCTAGTTCTTTTATAGAACTAGGCTTTTTTACTTTCTTCTTCTCGTTTCAAAAGCGAATTTGCCATCATT
TGGAAACAAAGAATTAAAAT

Product: internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKKFILASLACTTLISFSPLVGQVEVSAATTNIATAPEKNLQEAPPATVDQIFPDDALAFKVAQELGVSEDTVVTQEQLD
TIETMVYVDFGVEDLTGMEYLHNLKFVDLSQNKISNLENLANLTELETVSLNYNQITDITPLMNSPKLYNLELGVNQIST
LPSFENLTNLRILNLSSNQLKDISALKDTPQLTNLSISANNISDISVLSECDNLRVFYAESNQLTSIESLRNKTKLEYFD
ANFNQIKDVTPLSTIPTIRSIKIEENQISDFSSLAGHRLELFDATGQNIYLPDVALGDSTNIVMKDNLGVTLHDWVWYTP
GTYQNDTLTWENAGDNSAYFLNNQYPTYPSVTVTVYQTVTP

Sequences:

>Translated_361_residues
MKKFILASLACTTLISFSPLVGQVEVSAATTNIATAPEKNLQEAPPATVDQIFPDDALAFKVAQELGVSEDTVVTQEQLD
TIETMVYVDFGVEDLTGMEYLHNLKFVDLSQNKISNLENLANLTELETVSLNYNQITDITPLMNSPKLYNLELGVNQIST
LPSFENLTNLRILNLSSNQLKDISALKDTPQLTNLSISANNISDISVLSECDNLRVFYAESNQLTSIESLRNKTKLEYFD
ANFNQIKDVTPLSTIPTIRSIKIEENQISDFSSLAGHRLELFDATGQNIYLPDVALGDSTNIVMKDNLGVTLHDWVWYTP
GTYQNDTLTWENAGDNSAYFLNNQYPTYPSVTVTVYQTVTP
>Mature_361_residues
MKKFILASLACTTLISFSPLVGQVEVSAATTNIATAPEKNLQEAPPATVDQIFPDDALAFKVAQELGVSEDTVVTQEQLD
TIETMVYVDFGVEDLTGMEYLHNLKFVDLSQNKISNLENLANLTELETVSLNYNQITDITPLMNSPKLYNLELGVNQIST
LPSFENLTNLRILNLSSNQLKDISALKDTPQLTNLSISANNISDISVLSECDNLRVFYAESNQLTSIESLRNKTKLEYFD
ANFNQIKDVTPLSTIPTIRSIKIEENQISDFSSLAGHRLELFDATGQNIYLPDVALGDSTNIVMKDNLGVTLHDWVWYTP
GTYQNDTLTWENAGDNSAYFLNNQYPTYPSVTVTVYQTVTP

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=205, Percent_Identity=31.219512195122, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI21389483, Length=160, Percent_Identity=30, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17554124, Length=180, Percent_Identity=31.6666666666667, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17531555, Length=199, Percent_Identity=31.1557788944724, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536161, Length=181, Percent_Identity=28.7292817679558, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358617, Length=177, Percent_Identity=34.4632768361582, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 40119; Mature: 40119

Theoretical pI: Translated: 3.99; Mature: 3.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFILASLACTTLISFSPLVGQVEVSAATTNIATAPEKNLQEAPPATVDQIFPDDALAF
CCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHCCCCHHHHCCCCHHHHH
KVAQELGVSEDTVVTQEQLDTIETMVYVDFGVEDLTGMEYLHNLKFVDLSQNKISNLENL
HHHHHHCCCCCCEECHHHHHHEEEEEEEECCCHHHHHHHHHHCCEEEECCCHHHHHHHHH
ANLTELETVSLNYNQITDITPLMNSPKLYNLELGVNQISTLPSFENLTNLRILNLSSNQL
HHHHHEEEEEECCCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCEEEEECCCCCH
KDISALKDTPQLTNLSISANNISDISVLSECDNLRVFYAESNQLTSIESLRNKTKLEYFD
HHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCEEEEEC
ANFNQIKDVTPLSTIPTIRSIKIEENQISDFSSLAGHRLELFDATGQNIYLPDVALGDST
CCHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCEEECCCEEECCCC
NIVMKDNLGVTLHDWVWYTPGTYQNDTLTWENAGDNSAYFLNNQYPTYPSVTVTVYQTVT
CEEEECCCCEEEEEEEEECCCCCCCCEEEECCCCCCCEEEECCCCCCCCCEEEEEEEEEC
P
C
>Mature Secondary Structure
MKKFILASLACTTLISFSPLVGQVEVSAATTNIATAPEKNLQEAPPATVDQIFPDDALAF
CCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHCCCCHHHHCCCCHHHHH
KVAQELGVSEDTVVTQEQLDTIETMVYVDFGVEDLTGMEYLHNLKFVDLSQNKISNLENL
HHHHHHCCCCCCEECHHHHHHEEEEEEEECCCHHHHHHHHHHCCEEEECCCHHHHHHHHH
ANLTELETVSLNYNQITDITPLMNSPKLYNLELGVNQISTLPSFENLTNLRILNLSSNQL
HHHHHEEEEEECCCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCEEEEECCCCCH
KDISALKDTPQLTNLSISANNISDISVLSECDNLRVFYAESNQLTSIESLRNKTKLEYFD
HHHHHHCCCCCCEEEEEECCCCCHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCEEEEEC
ANFNQIKDVTPLSTIPTIRSIKIEENQISDFSSLAGHRLELFDATGQNIYLPDVALGDST
CCHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCEEEEEECCCCEEECCCEEECCCC
NIVMKDNLGVTLHDWVWYTPGTYQNDTLTWENAGDNSAYFLNNQYPTYPSVTVTVYQTVT
CEEEECCCCEEEEEEEEECCCCCCCCEEEECCCCCCCEEEECCCCCCCCCEEEEEEEEEC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]