Click here to switch to the map view.

The map label for this gene is yicI [C]

Identifier: 226222812

GI number: 226222812

Start: 182272

End: 184563

Strand: Direct

Name: yicI [C]

Synonym: Lm4b_00180

Alternate gene names: 226222812

Gene position: 182272-184563 (Clockwise)

Preceding gene: 226222811

Following gene: 226222813

Centisome position: 6.26

GC content: 39.35

Gene sequence:

>2292_bases
ATGGATGCTTCCACAAGTTTTGCGATTCTACCATCTAATGTAAAACAAAAAACAGCTTTCGAAAGAAAAGTAAATCAAGT
GAAAACGGCTAGTTGGGCGAATAATTGCCTGACTGGCACACTTGATATCGGTCAGTTCAGTTGCTATTTTGTTAATGAAA
AAATTGCTCGCGTGACGGTGAACCCATTTGGAGAAGTGGATTTAACGCCTTCGATTGCTGCGATTCACGATACGGAAAAA
CAAGCGGCTAAATTTACAGAAACAACGGACGGCTATGAGCTTCATTTTGCGGATAAAGAGATTATTATTTGTAAAAATCC
TTTCCAAATTATTATGAAACAAGCTGGGAAGCGTATTTTCCAAACAGAAGGATTGGCAATTAATCGCTATAAAGAACACC
AAATTTCGATTCAAAGCGAACCAGGAACCGCGATTTTTGGTTTAGGTGAAAAAACGGGTGCCTTGAATAAAGCCGGTTCC
ATTATTAGTATGTGGAACACGGATGTATACAGTCCACATAATAAAGATACAGTGGAGTTATACCAATCCATTCCTTTCAT
GATTGCGGATACTGCGGAAACAACCTATGGCTTATTTTATGATAATTCGCATCGTACAGAATTTGATTTCCAAAGTTTTG
AAGAAATGTATACGATTTTAGCAGAAGGCGGACAAGCGAATTTATATGTTATTTTTGGTGAGGACACGAAAGAAGTTGTC
GCGAATTACACTGATTTAACTGGTAAAACACCACTTCCACCAAAATGGTCATTAGGTTATCATCAATCAAGGTATAGCTA
CACCTCGGAAGAAGAAGTGGAACGGATTGCGAATACTTTTAAAGAAAAAGAGATTCCGCTTGACTGTGTATTCATGGATA
TACATTACATGGATGATTTCCGCGTATTCACTTTTAACCCGGATACTTTTCCAAATGGACCAGAATTGATTGCGCGTCTT
CGGGAACAAAATATTGACGTTGTACCAATTGTCGATCCGGGAATTAAAAAAGATGTTGATTATTCTGTTTATCAAGAGGG
GATCAAACATAATTATTTCTGCACTAAATTAGAAGGTTCGATTTATTATGGGGATGTTTGGCCGGGTGTCAGTGCTTTCC
CTGATTTTCTAAGTACAACTGTTCAACATTGGTGGGGCGGTTTACACAAATTTTACACAGATTTAGGTATACGCGGGATT
TGGAATGATATGAATGAGCCGTCTGTATTCAATGAAAGTAAAACGATGGATTTAGATGTTGTGCATAATCTGGACGGGAA
AAATGTAACCCATAAAGAAGCGCATAATTTATATGGATTGTATATGAGTAAAGCTACTTTTGAAGGGTTAAAACGGCTTG
TGCCAAATGAACGTCCATTTTCACTCACTCGTGCTGGTTATGCGGGTGTTCAGCGTTATTCGGCGGTTTGGACAGGAGAT
AATCGTAGTCACTGGGAGCATTTGGAGATGTCGCTGCCGATGATTATGAATTTAGGATTATCGGGCGTTGCGTTTACCGG
TGCTGATGTTGGTGGATTTTCTTCAGATTGTACGAAAGAAATGTTGATTCGTTGGACGCAAGCTGGGGCCTTTTTACCAT
ATTTCAGAAATCACTGTGTACAAGATAGTATTTATCAAGAGCCATGGGCGTTTGGCGCGGATGCAGAGAAAATTGTGAAA
CAATATATTGAATTGCGCTATGCCTTTTTACCGTATATTTATACAGAATTCCAAAAAACGGCAGAGAGTGGTTTACCGCT
CGTTCGGCCGCTTTATATGGAGTTTAAAGATGAACGCGATTTAATTCAAGTGAATGATCAATTTATGCTAGGTGAAAATA
TCCTCGTTGCGCCAATCGTTCGTGAAGGCCAAGTGAAGCGTCTAGTTCGTTTGCCAAGAGGGCTTTGGTTTAATTATTGG
ACAAAAGAGCAGTTCGTGGGCGGCGACTATATTATCGCAGACGCGCCGATTGATACCATGCCAATTTACATTAAAGCGGG
GACAATTCTGCCAGTTGGTAGCAGCGTTCAAAATACAAAAGAGACGCAAGATTTGACATTAGAAGTTTACTTAGATGGCG
ACGTAGCAAGCGGTTATGTGTATAATGATGATGGTAAAAGTTACCATTATGAAAGCGGCGCAGCATCCAAAACAACACTC
ACAGCTACTTTCAAAAATGGCGAAGTACTAATAAATGCTACCCATCAAGGTGAAGCAAACTTGCAACATAAAGTAACTAC
TATACAAGTTTTTGGAGAAAAAACAGACAAAATTACAAGGGCGGGAATTTAA

Upstream 100 bases:

>100_bases
CGGACGAAGTAGTTGTTTCTGTTCAAACAAACACACCGGCATATGAAGTTGAAGTAATCGGCACGACCAAAAAAGTACAA
ATAAAGAAAGGGAGATAATG

Downstream 100 bases:

>100_bases
TCTATGAAAGAAAAAGATTGGTGGAAAAAAAGCGTAGTGTACCAAATCTATCCAAAGAGTTTTAATGATTCGAATGGTGA
TGGAGTTGGTGATATTCAAG

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 763; Mature: 763

Protein sequence:

>763_residues
MDASTSFAILPSNVKQKTAFERKVNQVKTASWANNCLTGTLDIGQFSCYFVNEKIARVTVNPFGEVDLTPSIAAIHDTEK
QAAKFTETTDGYELHFADKEIIICKNPFQIIMKQAGKRIFQTEGLAINRYKEHQISIQSEPGTAIFGLGEKTGALNKAGS
IISMWNTDVYSPHNKDTVELYQSIPFMIADTAETTYGLFYDNSHRTEFDFQSFEEMYTILAEGGQANLYVIFGEDTKEVV
ANYTDLTGKTPLPPKWSLGYHQSRYSYTSEEEVERIANTFKEKEIPLDCVFMDIHYMDDFRVFTFNPDTFPNGPELIARL
REQNIDVVPIVDPGIKKDVDYSVYQEGIKHNYFCTKLEGSIYYGDVWPGVSAFPDFLSTTVQHWWGGLHKFYTDLGIRGI
WNDMNEPSVFNESKTMDLDVVHNLDGKNVTHKEAHNLYGLYMSKATFEGLKRLVPNERPFSLTRAGYAGVQRYSAVWTGD
NRSHWEHLEMSLPMIMNLGLSGVAFTGADVGGFSSDCTKEMLIRWTQAGAFLPYFRNHCVQDSIYQEPWAFGADAEKIVK
QYIELRYAFLPYIYTEFQKTAESGLPLVRPLYMEFKDERDLIQVNDQFMLGENILVAPIVREGQVKRLVRLPRGLWFNYW
TKEQFVGGDYIIADAPIDTMPIYIKAGTILPVGSSVQNTKETQDLTLEVYLDGDVASGYVYNDDGKSYHYESGAASKTTL
TATFKNGEVLINATHQGEANLQHKVTTIQVFGEKTDKITRAGI

Sequences:

>Translated_763_residues
MDASTSFAILPSNVKQKTAFERKVNQVKTASWANNCLTGTLDIGQFSCYFVNEKIARVTVNPFGEVDLTPSIAAIHDTEK
QAAKFTETTDGYELHFADKEIIICKNPFQIIMKQAGKRIFQTEGLAINRYKEHQISIQSEPGTAIFGLGEKTGALNKAGS
IISMWNTDVYSPHNKDTVELYQSIPFMIADTAETTYGLFYDNSHRTEFDFQSFEEMYTILAEGGQANLYVIFGEDTKEVV
ANYTDLTGKTPLPPKWSLGYHQSRYSYTSEEEVERIANTFKEKEIPLDCVFMDIHYMDDFRVFTFNPDTFPNGPELIARL
REQNIDVVPIVDPGIKKDVDYSVYQEGIKHNYFCTKLEGSIYYGDVWPGVSAFPDFLSTTVQHWWGGLHKFYTDLGIRGI
WNDMNEPSVFNESKTMDLDVVHNLDGKNVTHKEAHNLYGLYMSKATFEGLKRLVPNERPFSLTRAGYAGVQRYSAVWTGD
NRSHWEHLEMSLPMIMNLGLSGVAFTGADVGGFSSDCTKEMLIRWTQAGAFLPYFRNHCVQDSIYQEPWAFGADAEKIVK
QYIELRYAFLPYIYTEFQKTAESGLPLVRPLYMEFKDERDLIQVNDQFMLGENILVAPIVREGQVKRLVRLPRGLWFNYW
TKEQFVGGDYIIADAPIDTMPIYIKAGTILPVGSSVQNTKETQDLTLEVYLDGDVASGYVYNDDGKSYHYESGAASKTTL
TATFKNGEVLINATHQGEANLQHKVTTIQVFGEKTDKITRAGI
>Mature_763_residues
MDASTSFAILPSNVKQKTAFERKVNQVKTASWANNCLTGTLDIGQFSCYFVNEKIARVTVNPFGEVDLTPSIAAIHDTEK
QAAKFTETTDGYELHFADKEIIICKNPFQIIMKQAGKRIFQTEGLAINRYKEHQISIQSEPGTAIFGLGEKTGALNKAGS
IISMWNTDVYSPHNKDTVELYQSIPFMIADTAETTYGLFYDNSHRTEFDFQSFEEMYTILAEGGQANLYVIFGEDTKEVV
ANYTDLTGKTPLPPKWSLGYHQSRYSYTSEEEVERIANTFKEKEIPLDCVFMDIHYMDDFRVFTFNPDTFPNGPELIARL
REQNIDVVPIVDPGIKKDVDYSVYQEGIKHNYFCTKLEGSIYYGDVWPGVSAFPDFLSTTVQHWWGGLHKFYTDLGIRGI
WNDMNEPSVFNESKTMDLDVVHNLDGKNVTHKEAHNLYGLYMSKATFEGLKRLVPNERPFSLTRAGYAGVQRYSAVWTGD
NRSHWEHLEMSLPMIMNLGLSGVAFTGADVGGFSSDCTKEMLIRWTQAGAFLPYFRNHCVQDSIYQEPWAFGADAEKIVK
QYIELRYAFLPYIYTEFQKTAESGLPLVRPLYMEFKDERDLIQVNDQFMLGENILVAPIVREGQVKRLVRLPRGLWFNYW
TKEQFVGGDYIIADAPIDTMPIYIKAGTILPVGSSVQNTKETQDLTLEVYLDGDVASGYVYNDDGKSYHYESGAASKTTL
TATFKNGEVLINATHQGEANLQHKVTTIQVFGEKTDKITRAGI

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI66346737, Length=630, Percent_Identity=34.4444444444444, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI38202257, Length=644, Percent_Identity=32.4534161490683, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI88900491, Length=644, Percent_Identity=32.4534161490683, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI119393895, Length=702, Percent_Identity=30.9116809116809, Blast_Score=332, Evalue=1e-90,
Organism=Homo sapiens, GI119393893, Length=702, Percent_Identity=30.9116809116809, Blast_Score=332, Evalue=1e-90,
Organism=Homo sapiens, GI119393891, Length=702, Percent_Identity=30.9116809116809, Blast_Score=332, Evalue=1e-90,
Organism=Homo sapiens, GI221316699, Length=669, Percent_Identity=28.9985052316891, Blast_Score=295, Evalue=1e-79,
Organism=Homo sapiens, GI157364974, Length=659, Percent_Identity=28.8315629742033, Blast_Score=283, Evalue=5e-76,
Organism=Homo sapiens, GI310115361, Length=525, Percent_Identity=29.9047619047619, Blast_Score=243, Evalue=6e-64,
Organism=Homo sapiens, GI153791946, Length=462, Percent_Identity=23.1601731601732, Blast_Score=97, Evalue=7e-20,
Organism=Escherichia coli, GI2367256, Length=594, Percent_Identity=26.7676767676768, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI2367323, Length=631, Percent_Identity=24.0887480190174, Blast_Score=156, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71991189, Length=584, Percent_Identity=36.472602739726, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17560798, Length=650, Percent_Identity=34.6153846153846, Blast_Score=394, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17560800, Length=627, Percent_Identity=35.2472089314195, Blast_Score=394, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71985706, Length=606, Percent_Identity=27.0627062706271, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI32563849, Length=688, Percent_Identity=25, Blast_Score=199, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6319706, Length=672, Percent_Identity=30.3571428571429, Blast_Score=322, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24643749, Length=587, Percent_Identity=33.5604770017036, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24643753, Length=587, Percent_Identity=33.5604770017036, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24643751, Length=587, Percent_Identity=33.5604770017036, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24643746, Length=587, Percent_Identity=33.5604770017036, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI21357605, Length=587, Percent_Identity=33.5604770017036, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24650054, Length=390, Percent_Identity=26.1538461538462, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 86461; Mature: 86461

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00129 GLYCOSYL_HYDROL_F31_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASTSFAILPSNVKQKTAFERKVNQVKTASWANNCLTGTLDIGQFSCYFVNEKIARVTV
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCEEEEEEE
NPFGEVDLTPSIAAIHDTEKQAAKFTETTDGYELHFADKEIIICKNPFQIIMKQAGKRIF
CCCCCCCCCCCEEEEECCHHHHHHHCCCCCCEEEEECCCEEEEECCHHHHHHHHHCCCEE
QTEGLAINRYKEHQISIQSEPGTAIFGLGEKTGALNKAGSIISMWNTDVYSPHNKDTVEL
CCCCEEEECEECEEEEEECCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHH
YQSIPFMIADTAETTYGLFYDNSHRTEFDFQSFEEMYTILAEGGQANLYVIFGEDTKEVV
HHHCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHH
ANYTDLTGKTPLPPKWSLGYHQSRYSYTSEEEVERIANTFKEKEIPLDCVFMDIHYMDDF
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCE
RVFTFNPDTFPNGPELIARLREQNIDVVPIVDPGIKKDVDYSVYQEGIKHNYFCTKLEGS
EEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHCCCCCEEEEEECCC
IYYGDVWPGVSAFPDFLSTTVQHWWGGLHKFYTDLGIRGIWNDMNEPSVFNESKTMDLDV
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCEEEEE
VHNLDGKNVTHKEAHNLYGLYMSKATFEGLKRLVPNERPFSLTRAGYAGVQRYSAVWTGD
EECCCCCCCCHHHHHCEEEEEEHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHEEEEEECC
NRSHWEHLEMSLPMIMNLGLSGVAFTGADVGGFSSDCTKEMLIRWTQAGAFLPYFRNHCV
CCCCHHHHHHCCCHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
QDSIYQEPWAFGADAEKIVKQYIELRYAFLPYIYTEFQKTAESGLPLVRPLYMEFKDERD
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCC
LIQVNDQFMLGENILVAPIVREGQVKRLVRLPRGLWFNYWTKEQFVGGDYIIADAPIDTM
EEEECCEEEECCCEEEEEECCCCHHHHHHHCCCCCEEEECCHHHCCCCCEEEECCCCCCE
PIYIKAGTILPVGSSVQNTKETQDLTLEVYLDGDVASGYVYNDDGKSYHYESGAASKTTL
EEEEEECEEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCEEEECCCCCCCEEE
TATFKNGEVLINATHQGEANLQHKVTTIQVFGEKTDKITRAGI
EEEECCCEEEEEECCCCCCCCEEEEEEEEEECCCCCCHHCCCC
>Mature Secondary Structure
MDASTSFAILPSNVKQKTAFERKVNQVKTASWANNCLTGTLDIGQFSCYFVNEKIARVTV
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCEEEEEEE
NPFGEVDLTPSIAAIHDTEKQAAKFTETTDGYELHFADKEIIICKNPFQIIMKQAGKRIF
CCCCCCCCCCCEEEEECCHHHHHHHCCCCCCEEEEECCCEEEEECCHHHHHHHHHCCCEE
QTEGLAINRYKEHQISIQSEPGTAIFGLGEKTGALNKAGSIISMWNTDVYSPHNKDTVEL
CCCCEEEECEECEEEEEECCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHH
YQSIPFMIADTAETTYGLFYDNSHRTEFDFQSFEEMYTILAEGGQANLYVIFGEDTKEVV
HHHCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHH
ANYTDLTGKTPLPPKWSLGYHQSRYSYTSEEEVERIANTFKEKEIPLDCVFMDIHYMDDF
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEECCE
RVFTFNPDTFPNGPELIARLREQNIDVVPIVDPGIKKDVDYSVYQEGIKHNYFCTKLEGS
EEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHCCCCCEEEEEECCC
IYYGDVWPGVSAFPDFLSTTVQHWWGGLHKFYTDLGIRGIWNDMNEPSVFNESKTMDLDV
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCEEEEE
VHNLDGKNVTHKEAHNLYGLYMSKATFEGLKRLVPNERPFSLTRAGYAGVQRYSAVWTGD
EECCCCCCCCHHHHHCEEEEEEHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHEEEEEECC
NRSHWEHLEMSLPMIMNLGLSGVAFTGADVGGFSSDCTKEMLIRWTQAGAFLPYFRNHCV
CCCCHHHHHHCCCHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
QDSIYQEPWAFGADAEKIVKQYIELRYAFLPYIYTEFQKTAESGLPLVRPLYMEFKDERD
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCC
LIQVNDQFMLGENILVAPIVREGQVKRLVRLPRGLWFNYWTKEQFVGGDYIIADAPIDTM
EEEECCEEEECCCEEEEEECCCCHHHHHHHCCCCCEEEECCHHHCCCCCEEEECCCCCCE
PIYIKAGTILPVGSSVQNTKETQDLTLEVYLDGDVASGYVYNDDGKSYHYESGAASKTTL
EEEEEECEEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEECCCCCEEEECCCCCCCEEE
TATFKNGEVLINATHQGEANLQHKVTTIQVFGEKTDKITRAGI
EEEECCCEEEEEECCCCCCCCEEEEEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]