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The map label for this gene is xylR [H]

Identifier: 226222807

GI number: 226222807

Start: 174624

End: 175838

Strand: Direct

Name: xylR [H]

Synonym: Lm4b_00175

Alternate gene names: 226222807

Gene position: 174624-175838 (Clockwise)

Preceding gene: 226222806

Following gene: 226222808

Centisome position: 6.0

GC content: 37.28

Gene sequence:

>1215_bases
ATGGATATCTTAAGAAAAGGGAATAAAGACTTAATTAAAGACATAAACCGCTACACCGTGCTGAATTTAATCCGTGAAAA
AGGAGAAATCACGCGGACTGAGATAGCCAAAAAATGCGATTTTGGGATGTCTACATTAACGTATATTTTAGATGATTTAC
AGCAAGAAGGCATTATTTTGGAAGGTGCCGAAACATCATCTACTGGAGGCAGACGTGCCAAGTTAGTTAGATTTAATAAA
GATTATGGATTTGTTGTTAGTGTCAAAGTTGAAGAGGAACAACTTCTTTTTGCGTTGACCGATTTAAATGCAGAAATCAT
GGAAAATACTTCTATACCATTTTCCTCAGAGAAAAAACCAGAAGAAGCGATTGAGTTAATTGCTAAAAATGTGAAAAAGA
TGTGTGAAAACAGAGATATGAACCATTTGCTAGGAGTTGGAATTGCGATTTCCGGCCTAGTTAATCGTAGAAAAGGAACA
GTTATCCGCTCTACTATGTTAGGGTGGGAAAATGTCGCTTTAGAAGCAATGCTACATGCTTACTTCCCAGATATTCCAGT
GTACGTAGATAAAAATATAAACTGCTACACACTCGCGGAACTATGGTTAGGTGAAGGAAAACAATCAAATAATTTTGCAA
CAGTTTCCGTTGGAGCTGGACTTGGTTTATCCGTTGTTATTAATCGTCAAATTTATTATGGTGCACAGGGTGGAGCCGGT
GAATTTGGACATACAACGATTCAACCGGGCGGATACAAATGTCACTGTGGTCAAAAAGGATGCTTAGAAATGTACGCATC
CGAATTTTATTTCCGAAATCGTGGCGAAGAATTAAAAGAAGCTTATCCAACATCAGAATTAAAGGATTTTCATTTTGATA
AAGTAGCAAAAAGTGCTCGAGCTGGAGACGAAATGGCGACGGAACTTATGGGTAAAATGGGTGAATATTTAGGATACGGG
ATTCGAAATATTATTAATACCTTCAATCCGGAAAAAGTTATCATTGTCGGTGAAGGCTTGCACCATAGAGACTTATTCTT
AACTAAAATTGATGAAATTGCTTCACAAAACTTTTTTTCAGGGGCTGGCTTTGAAACGGAAATTACTACAACTTCTTTAG
AGGATCCTGCATGGTTACAAGGTGCGGCTTTACTAGTCATTCACCAATTATTCCAAGTGCCAATCTATGAAGAAGAACAA
ACGTTACTACGTTAA

Upstream 100 bases:

>100_bases
AAAAGATTGCATATTGCAAACGATTACAATATAATGTAACTATACTTACTTAATTCATTGAACGAAGTAAGTGGTCGGAC
AGAAGTAAAGGAGCTTGAAA

Downstream 100 bases:

>100_bases
AAAGAACATAAACTATTTCAGGAGGTTATTTTTACATGGTTGGTATGACTAGAAAGAAAACACTCTTTTGGCTATGCATA
TTCTTGCTACCCAATTTACT

Product: xylose repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MDILRKGNKDLIKDINRYTVLNLIREKGEITRTEIAKKCDFGMSTLTYILDDLQQEGIILEGAETSSTGGRRAKLVRFNK
DYGFVVSVKVEEEQLLFALTDLNAEIMENTSIPFSSEKKPEEAIELIAKNVKKMCENRDMNHLLGVGIAISGLVNRRKGT
VIRSTMLGWENVALEAMLHAYFPDIPVYVDKNINCYTLAELWLGEGKQSNNFATVSVGAGLGLSVVINRQIYYGAQGGAG
EFGHTTIQPGGYKCHCGQKGCLEMYASEFYFRNRGEELKEAYPTSELKDFHFDKVAKSARAGDEMATELMGKMGEYLGYG
IRNIINTFNPEKVIIVGEGLHHRDLFLTKIDEIASQNFFSGAGFETEITTTSLEDPAWLQGAALLVIHQLFQVPIYEEEQ
TLLR

Sequences:

>Translated_404_residues
MDILRKGNKDLIKDINRYTVLNLIREKGEITRTEIAKKCDFGMSTLTYILDDLQQEGIILEGAETSSTGGRRAKLVRFNK
DYGFVVSVKVEEEQLLFALTDLNAEIMENTSIPFSSEKKPEEAIELIAKNVKKMCENRDMNHLLGVGIAISGLVNRRKGT
VIRSTMLGWENVALEAMLHAYFPDIPVYVDKNINCYTLAELWLGEGKQSNNFATVSVGAGLGLSVVINRQIYYGAQGGAG
EFGHTTIQPGGYKCHCGQKGCLEMYASEFYFRNRGEELKEAYPTSELKDFHFDKVAKSARAGDEMATELMGKMGEYLGYG
IRNIINTFNPEKVIIVGEGLHHRDLFLTKIDEIASQNFFSGAGFETEITTTSLEDPAWLQGAALLVIHQLFQVPIYEEEQ
TLLR
>Mature_404_residues
MDILRKGNKDLIKDINRYTVLNLIREKGEITRTEIAKKCDFGMSTLTYILDDLQQEGIILEGAETSSTGGRRAKLVRFNK
DYGFVVSVKVEEEQLLFALTDLNAEIMENTSIPFSSEKKPEEAIELIAKNVKKMCENRDMNHLLGVGIAISGLVNRRKGT
VIRSTMLGWENVALEAMLHAYFPDIPVYVDKNINCYTLAELWLGEGKQSNNFATVSVGAGLGLSVVINRQIYYGAQGGAG
EFGHTTIQPGGYKCHCGQKGCLEMYASEFYFRNRGEELKEAYPTSELKDFHFDKVAKSARAGDEMATELMGKMGEYLGYG
IRNIINTFNPEKVIIVGEGLHHRDLFLTKIDEIASQNFFSGAGFETEITTTSLEDPAWLQGAALLVIHQLFQVPIYEEEQ
TLLR

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=229, Percent_Identity=32.7510917030568, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4885285, Length=227, Percent_Identity=33.0396475770925, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI298566315, Length=227, Percent_Identity=33.0396475770925, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI190014632, Length=227, Percent_Identity=33.0396475770925, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1786891, Length=337, Percent_Identity=30.2670623145401, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787878, Length=392, Percent_Identity=21.6836734693878, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI87082127, Length=351, Percent_Identity=23.6467236467236, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787363, Length=250, Percent_Identity=24.4, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 45201; Mature: 45201

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILRKGNKDLIKDINRYTVLNLIREKGEITRTEIAKKCDFGMSTLTYILDDLQQEGIIL
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEE
EGAETSSTGGRRAKLVRFNKDYGFVVSVKVEEEQLLFALTDLNAEIMENTSIPFSSEKKP
ECCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEECCCHHHHHCCCCCCCCCCCH
EEAIELIAKNVKKMCENRDMNHLLGVGIAISGLVNRRKGTVIRSTMLGWENVALEAMLHA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHH
YFPDIPVYVDKNINCYTLAELWLGEGKQSNNFATVSVGAGLGLSVVINRQIYYGAQGGAG
HCCCCCEEECCCCCEEEEHHHHHCCCCCCCCEEEEEECCCCCEEEEEECEEEECCCCCCC
EFGHTTIQPGGYKCHCGQKGCLEMYASEFYFRNRGEELKEAYPTSELKDFHFDKVAKSAR
CCCCCEECCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHH
AGDEMATELMGKMGEYLGYGIRNIINTFNPEKVIIVGEGLHHRDLFLTKIDEIASQNFFS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCC
GAGFETEITTTSLEDPAWLQGAALLVIHQLFQVPIYEEEQTLLR
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCC
>Mature Secondary Structure
MDILRKGNKDLIKDINRYTVLNLIREKGEITRTEIAKKCDFGMSTLTYILDDLQQEGIIL
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEE
EGAETSSTGGRRAKLVRFNKDYGFVVSVKVEEEQLLFALTDLNAEIMENTSIPFSSEKKP
ECCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEECCCHHHHHCCCCCCCCCCCH
EEAIELIAKNVKKMCENRDMNHLLGVGIAISGLVNRRKGTVIRSTMLGWENVALEAMLHA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHH
YFPDIPVYVDKNINCYTLAELWLGEGKQSNNFATVSVGAGLGLSVVINRQIYYGAQGGAG
HCCCCCEEECCCCCEEEEHHHHHCCCCCCCCEEEEEECCCCCEEEEEECEEEECCCCCCC
EFGHTTIQPGGYKCHCGQKGCLEMYASEFYFRNRGEELKEAYPTSELKDFHFDKVAKSAR
CCCCCEECCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHH
AGDEMATELMGKMGEYLGYGIRNIINTFNPEKVIIVGEGLHHRDLFLTKIDEIASQNFFS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCC
GAGFETEITTTSLEDPAWLQGAALLVIHQLFQVPIYEEEQTLLR
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA