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The map label for this gene is adcB [H]

Identifier: 226222789

GI number: 226222789

Start: 152647

End: 153453

Strand: Direct

Name: adcB [H]

Synonym: Lm4b_00155

Alternate gene names: 226222789

Gene position: 152647-153453 (Clockwise)

Preceding gene: 226222788

Following gene: 226222791

Centisome position: 5.24

GC content: 41.26

Gene sequence:

>807_bases
ATGGAAATGTTTCTCTATGGATTTATGCAAAGAGCCTTCCAAGCATCAATGATAATTGCTATAATTGCTCCTCTTTTAGG
AGTTTTCTTGATTATTCGAAGACAGTCACTTATGGCGGATACGCTTTCGCATGTGTCGCTTGCAGGTGTGGCCTTTGGGT
TGGTTTTAAATGTGAATCCCAGTGTGACAACGCTTATTGTAGTAGTTATTGCGGCGCTCGGGATTGAGTATTTGCGCGGG
GTTTATGCAACTTATTCAGAGTTGTCCATTGCGATACTAATGGCTGGTGGACTTGCTGTGGCGTTAGTGTTGATGAGTTT
GGATCAGGGTGGAATTACAACAAGCGTGCAGCAATACTTATTTGGTTCGATTGTAACAATCAGTAAGGCGCAAGTGCAGC
TGTTGGTAATTTTAGGAGTAGCTATCGTAGTATTGTTCTTAGTGTTTAAAAGGTTTATGTTTGTACTTACTTTTAGTGAA
GATGTTGCAGTTGCAGAAGGAGTCCCTGTGCGTTTGATTTCGCTTTTATTCAGTGTGGTTACTGGGATTGCGATTGCTGT
TATTATGCCAATAGCCGGAGCGTTACTCGTTTCAGCACTTATTATATTACCAGCTGCAATCGGTATGCGAATTTCAAAAG
GGTTCCTGATGTGTGTTATTAGTGCAATTCTGATTGGCTTAGTCGGAATGTTTTCCGGCCTTGTGTCTTCCTACCAACTA
GGAACCCCACCTGGCGCAACAATTACCTTAATGTTTATCATTCTTTTCATTATTTCGACCGTTGTTTTAAAAATGGCACG
GAAATGA

Upstream 100 bases:

>100_bases
AAGTACATGGTAAAGCGATTTTAATGGTAACGCACGATAGTGAAGAAATGGAAGATTTTGTCGATAAGCATATTCGCCTT
ATTAGAAAGGAGGATGTGTC

Downstream 100 bases:

>100_bases
TTTTTAGAACGATGTTTGACCATTTTGTATCATTGCATAAAGCTCTTGGTCATGAATAATCCAACTTTTTTCTTTCTTTT
CAATCTGATTGGTTGTTTTG

Product: high-affinity zinc ABC transporter (membrane protein)

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MEMFLYGFMQRAFQASMIIAIIAPLLGVFLIIRRQSLMADTLSHVSLAGVAFGLVLNVNPSVTTLIVVVIAALGIEYLRG
VYATYSELSIAILMAGGLAVALVLMSLDQGGITTSVQQYLFGSIVTISKAQVQLLVILGVAIVVLFLVFKRFMFVLTFSE
DVAVAEGVPVRLISLLFSVVTGIAIAVIMPIAGALLVSALIILPAAIGMRISKGFLMCVISAILIGLVGMFSGLVSSYQL
GTPPGATITLMFIILFIISTVVLKMARK

Sequences:

>Translated_268_residues
MEMFLYGFMQRAFQASMIIAIIAPLLGVFLIIRRQSLMADTLSHVSLAGVAFGLVLNVNPSVTTLIVVVIAALGIEYLRG
VYATYSELSIAILMAGGLAVALVLMSLDQGGITTSVQQYLFGSIVTISKAQVQLLVILGVAIVVLFLVFKRFMFVLTFSE
DVAVAEGVPVRLISLLFSVVTGIAIAVIMPIAGALLVSALIILPAAIGMRISKGFLMCVISAILIGLVGMFSGLVSSYQL
GTPPGATITLMFIILFIISTVVLKMARK
>Mature_268_residues
MEMFLYGFMQRAFQASMIIAIIAPLLGVFLIIRRQSLMADTLSHVSLAGVAFGLVLNVNPSVTTLIVVVIAALGIEYLRG
VYATYSELSIAILMAGGLAVALVLMSLDQGGITTSVQQYLFGSIVTISKAQVQLLVILGVAIVVLFLVFKRFMFVLTFSE
DVAVAEGVPVRLISLLFSVVTGIAIAVIMPIAGALLVSALIILPAAIGMRISKGFLMCVISAILIGLVGMFSGLVSSYQL
GTPPGATITLMFIILFIISTVVLKMARK

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=248, Percent_Identity=33.8709677419355, Blast_Score=117, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 28391; Mature: 28391

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]