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The map label for this gene is dppE [H]

Identifier: 226222786

GI number: 226222786

Start: 149162

End: 150817

Strand: Reverse

Name: dppE [H]

Synonym: Lm4b_00152

Alternate gene names: 226222786

Gene position: 150817-149162 (Counterclockwise)

Preceding gene: 226222790

Following gene: 226222771

Centisome position: 5.18

GC content: 40.82

Gene sequence:

>1656_bases
ATGCATTTTTTAAAGAAAACATTGCCTATTTTTGCCATTTTGACAGTACTTTTACTTACAGCTTGCGGAAATGACAATGA
AAAATCTACGACAAAAACTTCCCCGGACAAAATTAAATTTCTTGAAACCAGTGAATTACTGACTTTAAATACGACAGCTG
AGGAAGACTTTGCTAGCTTCACCGCGCAAAACCAAGTCTTCGAGGGATTATACACACTTGATCAAAAAGATAACTTTGTT
CCTGGGGTTGCTGATGGAATGCCAGAAATCAGCGCTGACCAAACGAAATACACCATTAAATTAAAGAAAAATGCGAAATG
GTCCGATGGTTCTCAAGTAACCGCTGATGATTTCGTCTACGCGTGGCGCCGTGTCGTTGATCCAAAAACCGCACCTGGAT
ACTCCGCGCTCTTCAAAGATTCGATTAAAAACGCCACTGAAATCAATGAAGGCAAACTACCTGTAACTGACCTTGGTGTC
GTTGCTACTGACCCAACAACGCTTGAAATCACACTAAAAAAACCAGTTCCCTACTTCATTTCACTTCTTTCTTTTGAAAC
ATTTTTCCCACAAAAAGAAAGCTTTGTGAAAAAACAAGGCGACAAATACGGGACAGATAGTGCGCACACTTTGTACAATG
GTCCTTTTGTTATGAAGGATTGGGGCGGCAACATTACGAATAAATGGACTTACGCGAAAAACGACCAATATTGGGACAAA
GATAATGTCAAAGTAAATGAAATTGATGTGCAAGTCGCGAAAGATATTAACGCCGGCGTGAACCTTTATAATACAAACGA
AGCTGACCGCGTGCCACTTTCAGGCGATTTTGCGAAACAATACAAAGACAAGAAAGATTTCCAAACGGAAAAAGATGCGC
TGATTAGTTATTTGCGCATGAATCAAAAACGCGACGGTAAAGCGACTCCACTTGCGAATAATTCCTTGCGTCACGCGCTT
AATTTAGCTGTCGATAAGAAACAACTAACGGATCGGATTCTCGGTGACGGTTCCTTCCCAGCGAACGGACTTCTTCCAAA
AGATTTCGTCCAAAACCCAACAACGGGCGCTGATTTCCGCACAGATAGCGGCGACCATTTAGTTTATAACAAAGAAGAAG
CTTTAAAATATTGGAAACAAGCACAAAAAGAACTTGGCACTGACAAAGTAACAATTGAACTTCTCGGCGATGACCAAGAA
ACAACGAAAACCATTTTCGCTTATTTGAAAGCACAGTTTGAAGATAATTTGCCAGGTGTGACGATTAAAGTGAAAAATAT
GCCTTCGAAGAGCGCGACACAGCTAACTTCTGATGGTAATTATGACTTGTCACTGGCTGCTTGGATGCCTGACTTTAAAG
ATCCCTGGACGTATAGCAGTTTATTCTTATCCGATTACTTTAATAACCATATGAGTTACAACAGTCCTGCTTATGATAAA
CTTGTAAAATCGACTGATACAACACTTGCGACGAAACCAGAAGAACGTTGGAATGCATTCGTAGCTTCTGAGAAAGTTCT
GCTTGATGACGACGCGGCGATCTTACCACTTTATCAACATCAAACAGCAGTGTTGCAACGTACGGATATTACCGGCGTGC
AGAAACATGCTTTTGGTTCGCCTTATAGTTATAAGTTTATTCGGGTGGAGAAGTAA

Upstream 100 bases:

>100_bases
TTTTTGCGTCAAGTAGTTTTTTTGCCAAATCATTAACTTGACTTATCTTATCGGAATACTTATAATAACGATAAATACAC
AGATAGAAGGGGAGAAAACC

Downstream 100 bases:

>100_bases
TTCGCCAGTTTGGAAAAAGCCAGCAATTTTAAAAATTGCTGGCTTTTTGATTTATAAATTATTAAATTCTATCTTTGCAA
GTAAGCGTTTATCTTATTTA

Product: oligopeptide ABC transporter-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MHFLKKTLPIFAILTVLLLTACGNDNEKSTTKTSPDKIKFLETSELLTLNTTAEEDFASFTAQNQVFEGLYTLDQKDNFV
PGVADGMPEISADQTKYTIKLKKNAKWSDGSQVTADDFVYAWRRVVDPKTAPGYSALFKDSIKNATEINEGKLPVTDLGV
VATDPTTLEITLKKPVPYFISLLSFETFFPQKESFVKKQGDKYGTDSAHTLYNGPFVMKDWGGNITNKWTYAKNDQYWDK
DNVKVNEIDVQVAKDINAGVNLYNTNEADRVPLSGDFAKQYKDKKDFQTEKDALISYLRMNQKRDGKATPLANNSLRHAL
NLAVDKKQLTDRILGDGSFPANGLLPKDFVQNPTTGADFRTDSGDHLVYNKEEALKYWKQAQKELGTDKVTIELLGDDQE
TTKTIFAYLKAQFEDNLPGVTIKVKNMPSKSATQLTSDGNYDLSLAAWMPDFKDPWTYSSLFLSDYFNNHMSYNSPAYDK
LVKSTDTTLATKPEERWNAFVASEKVLLDDDAAILPLYQHQTAVLQRTDITGVQKHAFGSPYSYKFIRVEK

Sequences:

>Translated_551_residues
MHFLKKTLPIFAILTVLLLTACGNDNEKSTTKTSPDKIKFLETSELLTLNTTAEEDFASFTAQNQVFEGLYTLDQKDNFV
PGVADGMPEISADQTKYTIKLKKNAKWSDGSQVTADDFVYAWRRVVDPKTAPGYSALFKDSIKNATEINEGKLPVTDLGV
VATDPTTLEITLKKPVPYFISLLSFETFFPQKESFVKKQGDKYGTDSAHTLYNGPFVMKDWGGNITNKWTYAKNDQYWDK
DNVKVNEIDVQVAKDINAGVNLYNTNEADRVPLSGDFAKQYKDKKDFQTEKDALISYLRMNQKRDGKATPLANNSLRHAL
NLAVDKKQLTDRILGDGSFPANGLLPKDFVQNPTTGADFRTDSGDHLVYNKEEALKYWKQAQKELGTDKVTIELLGDDQE
TTKTIFAYLKAQFEDNLPGVTIKVKNMPSKSATQLTSDGNYDLSLAAWMPDFKDPWTYSSLFLSDYFNNHMSYNSPAYDK
LVKSTDTTLATKPEERWNAFVASEKVLLDDDAAILPLYQHQTAVLQRTDITGVQKHAFGSPYSYKFIRVEK
>Mature_551_residues
MHFLKKTLPIFAILTVLLLTACGNDNEKSTTKTSPDKIKFLETSELLTLNTTAEEDFASFTAQNQVFEGLYTLDQKDNFV
PGVADGMPEISADQTKYTIKLKKNAKWSDGSQVTADDFVYAWRRVVDPKTAPGYSALFKDSIKNATEINEGKLPVTDLGV
VATDPTTLEITLKKPVPYFISLLSFETFFPQKESFVKKQGDKYGTDSAHTLYNGPFVMKDWGGNITNKWTYAKNDQYWDK
DNVKVNEIDVQVAKDINAGVNLYNTNEADRVPLSGDFAKQYKDKKDFQTEKDALISYLRMNQKRDGKATPLANNSLRHAL
NLAVDKKQLTDRILGDGSFPANGLLPKDFVQNPTTGADFRTDSGDHLVYNKEEALKYWKQAQKELGTDKVTIELLGDDQE
TTKTIFAYLKAQFEDNLPGVTIKVKNMPSKSATQLTSDGNYDLSLAAWMPDFKDPWTYSSLFLSDYFNNHMSYNSPAYDK
LVKSTDTTLATKPEERWNAFVASEKVLLDDDAAILPLYQHQTAVLQRTDITGVQKHAFGSPYSYKFIRVEK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=539, Percent_Identity=29.1280148423006, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081878, Length=477, Percent_Identity=29.979035639413, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789397, Length=478, Percent_Identity=28.2426778242678, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787762, Length=460, Percent_Identity=23.0434782608696, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787052, Length=307, Percent_Identity=25.7328990228013, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62054; Mature: 62054

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFLKKTLPIFAILTVLLLTACGNDNEKSTTKTSPDKIKFLETSELLTLNTTAEEDFASF
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCHHHHHHH
TAQNQVFEGLYTLDQKDNFVPGVADGMPEISADQTKYTIKLKKNAKWSDGSQVTADDFVY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHH
AWRRVVDPKTAPGYSALFKDSIKNATEINEGKLPVTDLGVVATDPTTLEITLKKPVPYFI
HHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCEEECCCCEEEEEECCCCHHHH
SLLSFETFFPQKESFVKKQGDKYGTDSAHTLYNGPFVMKDWGGNITNKWTYAKNDQYWDK
HHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEECCCEEEECCCCCCCCCEEECCCCCCCCC
DNVKVNEIDVQVAKDINAGVNLYNTNEADRVPLSGDFAKQYKDKKDFQTEKDALISYLRM
CCCEEEEEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHCCHHHCCHHHHHHHHHHHH
NQKRDGKATPLANNSLRHALNLAVDKKQLTDRILGDGSFPANGLLPKDFVQNPTTGADFR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCC
TDSGDHLVYNKEEALKYWKQAQKELGTDKVTIELLGDDQETTKTIFAYLKAQFEDNLPGV
CCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCE
TIKVKNMPSKSATQLTSDGNYDLSLAAWMPDFKDPWTYSSLFLSDYFNNHMSYNSPAYDK
EEEEECCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHH
LVKSTDTTLATKPEERWNAFVASEKVLLDDDAAILPLYQHQTAVLQRTDITGVQKHAFGS
HHHCCCCEECCCCHHHHHHHHHCCEEEECCCCEEEEEHHHHHHHHHHCCCCCHHHHCCCC
PYSYKFIRVEK
CCEEEEEEEEC
>Mature Secondary Structure
MHFLKKTLPIFAILTVLLLTACGNDNEKSTTKTSPDKIKFLETSELLTLNTTAEEDFASF
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCHHHHHHH
TAQNQVFEGLYTLDQKDNFVPGVADGMPEISADQTKYTIKLKKNAKWSDGSQVTADDFVY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHH
AWRRVVDPKTAPGYSALFKDSIKNATEINEGKLPVTDLGVVATDPTTLEITLKKPVPYFI
HHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCEEECCCCEEEEEECCCCHHHH
SLLSFETFFPQKESFVKKQGDKYGTDSAHTLYNGPFVMKDWGGNITNKWTYAKNDQYWDK
HHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEECCCEEEECCCCCCCCCEEECCCCCCCCC
DNVKVNEIDVQVAKDINAGVNLYNTNEADRVPLSGDFAKQYKDKKDFQTEKDALISYLRM
CCCEEEEEEEEEECCCCCCCEEEECCCCCCCCCCCHHHHHHCCHHHCCHHHHHHHHHHHH
NQKRDGKATPLANNSLRHALNLAVDKKQLTDRILGDGSFPANGLLPKDFVQNPTTGADFR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCC
TDSGDHLVYNKEEALKYWKQAQKELGTDKVTIELLGDDQETTKTIFAYLKAQFEDNLPGV
CCCCCEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCE
TIKVKNMPSKSATQLTSDGNYDLSLAAWMPDFKDPWTYSSLFLSDYFNNHMSYNSPAYDK
EEEEECCCCCHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHH
LVKSTDTTLATKPEERWNAFVASEKVLLDDDAAILPLYQHQTAVLQRTDITGVQKHAFGS
HHHCCCCEECCCCHHHHHHHHHCCEEEECCCCEEEEEHHHHHHHHHHCCCCCHHHHCCCC
PYSYKFIRVEK
CCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]