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The map label for this gene is appB [H]

Identifier: 226222775

GI number: 226222775

Start: 141704

End: 142654

Strand: Direct

Name: appB [H]

Synonym: Lm4b_00140

Alternate gene names: 226222775

Gene position: 141704-142654 (Clockwise)

Preceding gene: 226222774

Following gene: 226222776

Centisome position: 4.87

GC content: 39.43

Gene sequence:

>951_bases
ATGCTAAAAACAATCATAAAACGCGTATTGCAAATTATTCCGATGCTATTTATTATCTCGATTATTTCGTTTGCACTTAT
AAAATTAGCGCCCGGGGATCCCGTGAATTCTTTTGTTACGCCTGATATGAATCCTGACGATGTGGAACGAATTAGACAAA
GTTTAGGACTTGATCAACCAATTTATGTGCAGTACTTTATTTGGCTTGGAAACTTGTTGCAAGGAAATCTTGGTTATTCG
ATTGTGAATAGCCAGCCAGTTTTGCAACAAATTTTAGAGAGAATTCCGGCGACACTTGGTTTGGTGGGAACTTCGCTTGT
TCTGACGCTATTATTATCGATTCCACTTGGTTTAGTTGCGGCGAATTACGAAAATACGTGGATTGATAAAGTATTAAACG
GGATTTCATATATTGGGATTTCGATTCCGATTTTTTGGTTTGGGATGATTTTAATAGATGTATTTTCGATTCAGCTAGGT
TGGCTTCCAAGTCTAGGGATGCGAACGATTGGGGTTGACTCTTTTTGGGATATGGCGGAGCATGCGATTTTACCAGTTAT
AACGCTGACTTTCCAAGGGTGTGCGGCATATTATCGTTACGTACGCTCGAATACCATCAACCAATTAAAAGAAGAATATG
TTTTGTTTGGTTATGCGAAAGGTCTATCCAAAGTGCAAATTATGGGGCATCATGTCTTGAAAAATTCCTTGCTACCAGTT
ATAACACTACTTGGGATGTCACTTCCGCAAGTCATTACAGGCGCTTTTATTACCGAAAGTATTTTTTCATGGCCGGGCAT
GGGCTCGCTTGGAATTAACGCGATTTTCCAATTAGATTATCCAGTTATTATGGCGATTACGCTATTTTCAGCGCTGTTAT
TAATTATCGGAAACTTGCTGGCCGATTTAGCTTATATGATTGTCGATCCGCGGATTAGGGAAATGGGGTGA

Upstream 100 bases:

>100_bases
AATTAAAAATCATTCGTAAAAAATCTGGCCTGCCATGCTTGTTTTTGGCAGGTTCAGGTTTTTACTTGTCATTTTTAGTG
TTTTAGATAGGAGATAAATT

Downstream 100 bases:

>100_bases
GGAGTTCATGATGCGATTAGATTTTTCGAAAAAAACAATGCAAGATTTCGAGCGGGATGCAGAAGTTGTTCACGCAACAC
GAGAGCGTAGTTTTTGGCGT

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLKTIIKRVLQIIPMLFIISIISFALIKLAPGDPVNSFVTPDMNPDDVERIRQSLGLDQPIYVQYFIWLGNLLQGNLGYS
IVNSQPVLQQILERIPATLGLVGTSLVLTLLLSIPLGLVAANYENTWIDKVLNGISYIGISIPIFWFGMILIDVFSIQLG
WLPSLGMRTIGVDSFWDMAEHAILPVITLTFQGCAAYYRYVRSNTINQLKEEYVLFGYAKGLSKVQIMGHHVLKNSLLPV
ITLLGMSLPQVITGAFITESIFSWPGMGSLGINAIFQLDYPVIMAITLFSALLLIIGNLLADLAYMIVDPRIREMG

Sequences:

>Translated_316_residues
MLKTIIKRVLQIIPMLFIISIISFALIKLAPGDPVNSFVTPDMNPDDVERIRQSLGLDQPIYVQYFIWLGNLLQGNLGYS
IVNSQPVLQQILERIPATLGLVGTSLVLTLLLSIPLGLVAANYENTWIDKVLNGISYIGISIPIFWFGMILIDVFSIQLG
WLPSLGMRTIGVDSFWDMAEHAILPVITLTFQGCAAYYRYVRSNTINQLKEEYVLFGYAKGLSKVQIMGHHVLKNSLLPV
ITLLGMSLPQVITGAFITESIFSWPGMGSLGINAIFQLDYPVIMAITLFSALLLIIGNLLADLAYMIVDPRIREMG
>Mature_316_residues
MLKTIIKRVLQIIPMLFIISIISFALIKLAPGDPVNSFVTPDMNPDDVERIRQSLGLDQPIYVQYFIWLGNLLQGNLGYS
IVNSQPVLQQILERIPATLGLVGTSLVLTLLLSIPLGLVAANYENTWIDKVLNGISYIGISIPIFWFGMILIDVFSIQLG
WLPSLGMRTIGVDSFWDMAEHAILPVITLTFQGCAAYYRYVRSNTINQLKEEYVLFGYAKGLSKVQIMGHHVLKNSLLPV
ITLLGMSLPQVITGAFITESIFSWPGMGSLGINAIFQLDYPVIMAITLFSALLLIIGNLLADLAYMIVDPRIREMG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=313, Percent_Identity=38.3386581469649, Blast_Score=237, Evalue=9e-64,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=37.3831775700935, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=33.5311572700297, Blast_Score=194, Evalue=5e-51,
Organism=Escherichia coli, GI1787761, Length=330, Percent_Identity=34.8484848484849, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1787497, Length=316, Percent_Identity=32.2784810126582, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=34.5588235294118, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1788504, Length=363, Percent_Identity=28.6501377410468, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35076; Mature: 35076

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTIIKRVLQIIPMLFIISIISFALIKLAPGDPVNSFVTPDMNPDDVERIRQSLGLDQP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
IYVQYFIWLGNLLQGNLGYSIVNSQPVLQQILERIPATLGLVGTSLVLTLLLSIPLGLVA
HHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
ANYENTWIDKVLNGISYIGISIPIFWFGMILIDVFSIQLGWLPSLGMRTIGVDSFWDMAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHH
HAILPVITLTFQGCAAYYRYVRSNTINQLKEEYVLFGYAKGLSKVQIMGHHVLKNSLLPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
ITLLGMSLPQVITGAFITESIFSWPGMGSLGINAIFQLDYPVIMAITLFSALLLIIGNLL
HHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCHHHHHHHHHHHHHHHHHHHHH
ADLAYMIVDPRIREMG
HHHHHHHHCCHHHHCC
>Mature Secondary Structure
MLKTIIKRVLQIIPMLFIISIISFALIKLAPGDPVNSFVTPDMNPDDVERIRQSLGLDQP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
IYVQYFIWLGNLLQGNLGYSIVNSQPVLQQILERIPATLGLVGTSLVLTLLLSIPLGLVA
HHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
ANYENTWIDKVLNGISYIGISIPIFWFGMILIDVFSIQLGWLPSLGMRTIGVDSFWDMAE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHH
HAILPVITLTFQGCAAYYRYVRSNTINQLKEEYVLFGYAKGLSKVQIMGHHVLKNSLLPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
ITLLGMSLPQVITGAFITESIFSWPGMGSLGINAIFQLDYPVIMAITLFSALLLIIGNLL
HHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHEECCHHHHHHHHHHHHHHHHHHHHH
ADLAYMIVDPRIREMG
HHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]