Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 226222776

GI number: 226222776

Start: 142665

End: 143558

Strand: Direct

Name: appC [H]

Synonym: Lm4b_00141

Alternate gene names: 226222776

Gene position: 142665-143558 (Clockwise)

Preceding gene: 226222775

Following gene: 226222777

Centisome position: 4.9

GC content: 44.3

Gene sequence:

>894_bases
ATGCGATTAGATTTTTCGAAAAAAACAATGCAAGATTTCGAGCGGGATGCAGAAGTTGTTCACGCAACACGAGAGCGTAG
TTTTTGGCGTTTTATGCTTGCTGACCGCCGAGCTGTTTTTGCGACGAGTGTGCTAATACTTATTACGGTGGCTTGTATTT
TCGCGTTCCTTTCGCCTTATGACCCTAATGCTCTTTCCGTTCAGGACAAACTGATGCCGCCAAATTCGTCGCACTGGTTT
GGGACGGATGACCATGGTCGGGATTACTTGACGCGTGTCTTGTACGGTGGCCGGGTTTCACTACTTGTCGGTGTATTTGC
GATGATGATTGCCGTTGTCGTTGGAACGCTTGCCGGGACAGTTAGTGGCTACTTTGGTGGATTCATTGACAATATGGTGA
TGCGTTTTCTTGATATTTTCATGTCGATTCCGTCATTTTTCCTACTAATGATTTTAAATGCATACTTAAAACCGGGAATT
TCGAACATTATTATCATTATCGGATTGCTTTCTTGGATGGAAGTGGCGCGGATAGTTCGAGCGGAGACGTTAACATTAAA
AGAACGTGAATTCATTTTATACTCCAAGTCATCAGGTGGCGGATTTTTCCACATCATGTTCAAGCACATTATTCCAAATG
CGATGCCATCCATCGTCGTTGCAGCTTCATTAAACGTCGCTACAGCCATTTTAACCGAGTCAGCACTAAGTTTCCTTGGC
TTAGGCGTTCAACAGCCTAACGCTTCGTGGGGCAGCATGCTGAACAATGCGCAAGGTTACGTCGGCGAAGCAACATACTT
GGCGCTTTTCCCTGGATTACTAATTTTAATGACCATCCTTTCATTCAACGTCCTTGGTGATGTACTGAGAAAAGGGTTAT
CACGTAGATATTAA

Upstream 100 bases:

>100_bases
CTATTTTCAGCGCTGTTATTAATTATCGGAAACTTGCTGGCCGATTTAGCTTATATGATTGTCGATCCGCGGATTAGGGA
AATGGGGTGAGGAGTTCATG

Downstream 100 bases:

>100_bases
ATTTAAAAACACTTTGATTTTTTCAGTCAAAGTGTTTTTTTGTTTTTTAAAGAAAAGGTACTTAAAATAGAAACGTAAAA
AACGTGTTTTAGCCAATTTC

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSPYDPNALSVQDKLMPPNSSHWF
GTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAGTVSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPGI
SNIIIIIGLLSWMEVARIVRAETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFLG
LGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY

Sequences:

>Translated_297_residues
MRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSPYDPNALSVQDKLMPPNSSHWF
GTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAGTVSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPGI
SNIIIIIGLLSWMEVARIVRAETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFLG
LGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY
>Mature_297_residues
MRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSPYDPNALSVQDKLMPPNSSHWF
GTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAGTVSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPGI
SNIIIIIGLLSWMEVARIVRAETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFLG
LGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=39.8550724637681, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787760, Length=259, Percent_Identity=37.8378378378378, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1787498, Length=302, Percent_Identity=41.0596026490066, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789889, Length=235, Percent_Identity=36.5957446808511, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1789964, Length=285, Percent_Identity=36.140350877193, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1788505, Length=224, Percent_Identity=32.1428571428571, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787549, Length=275, Percent_Identity=28, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33009; Mature: 33009

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPNALSVQDKLMPPNSSHWFGTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAGT
CCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPGISNIIIIIGLLSWMEVARIVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFLG
HHHHEEECCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY
CCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLDFSKKTMQDFERDAEVVHATRERSFWRFMLADRRAVFATSVLILITVACIFAFLSPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DPNALSVQDKLMPPNSSHWFGTDDHGRDYLTRVLYGGRVSLLVGVFAMMIAVVVGTLAGT
CCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
VSGYFGGFIDNMVMRFLDIFMSIPSFFLLMILNAYLKPGISNIIIIIGLLSWMEVARIVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AETLTLKEREFILYSKSSGGGFFHIMFKHIIPNAMPSIVVAASLNVATAILTESALSFLG
HHHHEEECCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVQQPNASWGSMLNNAQGYVGEATYLALFPGLLILMTILSFNVLGDVLRKGLSRRY
CCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]