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The map label for this gene is desK [H]

Identifier: 225861820

GI number: 225861820

Start: 1855072

End: 1856169

Strand: Reverse

Name: desK [H]

Synonym: SPT_1982

Alternate gene names: 225861820

Gene position: 1856169-1855072 (Counterclockwise)

Preceding gene: 225861821

Following gene: 225861819

Centisome position: 87.88

GC content: 38.8

Gene sequence:

>1098_bases
ATGCTTGAAAGACTGAAAAGCATACACTATATGTTTTGGACCAGTTTGATTTTTATGCTTTTTCCCATCCTACCTGTAGT
GATTGGGGAGCTTCCTGCTTGGCATTTATTGGTTGATATTCTATTTGTAGTGACGTATTTGGGTGTTTTAATAACTAAGA
ACCAGCGCCTATCTTGGCTTTTCTGGGGGATCATGCTGGTCTATGTAGCTGGGAATACCGCCTTTGTTGCTGGGAATTAT
ATCTGGTTTTTCTTTTTCCTTTCCAATATCTTAATTTATCATTTTGGCGTACGTAGTTTAAAGTCTTTACATGTATGGAC
ATTTCTCCTTGCTCAAGTCCTTGTTGTGGGGCGACTTTTGATTTTTCAGAGAATCGAAGTTGAGTTTCTAGTCTATATGC
TTGTAATTCTTACTTTTGTCGATTTGATGACTTTGGGCTCGGTTCGAATTCGCCTTGTCGAGGATTTGAAAGAAGCTCAG
GTCAAGCAAAATACCCAGATAAATCTATTGCTAGCAGAAAATGAGCGCAATCGTATCGGTCAGGATTTGCATGATAGTCT
GGGACATACCTTTGCTATGCTTAGTGTCAAGATAGATCTAGCCTTGCAGCTATTTCAAATGCAGGCTTATCCACAAGTGG
AAAAGGAATTAAGAGAAATACAGCAAATTAGCAAAGAATCAATGCGTGAAGTTCGAACCATTGTGGAAAATCTTAAGTCT
AGAACTTTGACATCCGAACTAGAGACTGTGAAAAAGATGTTAGAAATTGCTGGAATTGAGGTGGAAACAGATAACCAACT
AGATACTGCTAGCCTTACTCAAGAATTGGAGTCAATGGCTTCTATGATTTTGCTTGAGTTGGTGACCAATATCATCAAAC
ATGCCAAAGCGTCTAAAGCTTACTTAAAATTAGAACGGACAGAGAAGGAACTCATTTTAACAGTAAGTGATGATGGCTGC
GGCTTTGCTTTTCTAAAAGGAGATGAGCTCCATACAATCCGAGATCGTGTTTTTCCATTTTCAGGAGAAGTAAGTGTAAT
CAGTCAGAAACATCCAACGGAAGTGCAAGTTCGACTACCTTATAAGGAGAGAAACTAA

Upstream 100 bases:

>100_bases
AGGGTGGCATCAATCTATCAGCCACAGTTTATTTACTTGTTTTTTCAGCAGTTTTATTTGGTTTGACTATTTACCTTCAA
GGTCATAAGGAGAATGCTTA

Downstream 100 bases:

>100_bases
GATGAAAGTATTAGTCGCAGAAGATCAAAGTATGTTGCGAGATGCCATGTGTCAATTACTCACGCTTCAACCAGATGTGG
AGTCTGTCCTTCAAGCCAAG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNY
IWFFFFLSNILIYHFGVRSLKSLHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKIDLALQLFQMQAYPQVEKELREIQQISKESMREVRTIVENLKS
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGC
GFAFLKGDELHTIRDRVFPFSGEVSVISQKHPTEVQVRLPYKERN

Sequences:

>Translated_365_residues
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNY
IWFFFFLSNILIYHFGVRSLKSLHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKIDLALQLFQMQAYPQVEKELREIQQISKESMREVRTIVENLKS
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGC
GFAFLKGDELHTIRDRVFPFSGEVSVISQKHPTEVQVRLPYKERN
>Mature_365_residues
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNY
IWFFFFLSNILIYHFGVRSLKSLHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKIDLALQLFQMQAYPQVEKELREIQQISKESMREVRTIVENLKS
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGC
GFAFLKGDELHTIRDRVFPFSGEVSVISQKHPTEVQVRLPYKERN

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates desR by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42211; Mature: 42211

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FWGIMLVYVAGNTAFVAGNYIWFFFFLSNILIYHFGVRSLKSLHVWTFLLAQVLVVGRLL
HHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQVKQNTQINLLLAENERNRIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHCC
QDLHDSLGHTFAMLSVKIDLALQLFQMQAYPQVEKELREIQQISKESMREVRTIVENLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELESMASMILLELVTNIIKHAKASKA
HHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLKLERTEKELILTVSDDGCGFAFLKGDELHTIRDRVFPFSGEVSVISQKHPTEVQVRLP
HHHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCCCCEEEECCCCCCEEEEECC
YKERN
CCCCC
>Mature Secondary Structure
MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVVTYLGVLITKNQRLSWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FWGIMLVYVAGNTAFVAGNYIWFFFFLSNILIYHFGVRSLKSLHVWTFLLAQVLVVGRLL
HHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQVKQNTQINLLLAENERNRIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHCC
QDLHDSLGHTFAMLSVKIDLALQLFQMQAYPQVEKELREIQQISKESMREVRTIVENLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTLTSELETVKKMLEIAGIEVETDNQLDTASLTQELESMASMILLELVTNIIKHAKASKA
HHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLKLERTEKELILTVSDDGCGFAFLKGDELHTIRDRVFPFSGEVSVISQKHPTEVQVRLP
HHHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCCCCEEEECCCCCCEEEEECC
YKERN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]