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The map label for this gene is coaD [H]

Identifier: 225861786

GI number: 225861786

Start: 1826806

End: 1827294

Strand: Reverse

Name: coaD [H]

Synonym: SPT_1948

Alternate gene names: 225861786

Gene position: 1827294-1826806 (Counterclockwise)

Preceding gene: 225861787

Following gene: 225861785

Centisome position: 86.51

GC content: 40.29

Gene sequence:

>489_bases
ATGTCAGATAAGATTGGCTTATTCACAGGCTCATTTGATCCGATGACAAATGGGCATCTGGATATCATTGAACGGGCGAG
CAGACTCTTTGATAAGCTCTATGTCGGTATTTTTTTTAATCCCCACAAACAAGGATTTCTTCCTATCGAAAATCGTAAAC
GGGGGCTAGAAAAGGCTTTGGGACATCTGGAAAATGTTGAAGTCGTGGCTTCTCATGATGAATTGGTGGTCGATGTTGCA
AAAAGATTGGGGGCTACTTTCCTAGTACGGGGGTTGAGGAATGCGTCGGATTTGCAATATGAAGCCAGTTTTGATTACTA
CAATCATCAGCTGTCTTCTGATATAGAGACTATTTATTTACATAGTCGACCTGAACATCTCTATATCAGTTCATCAGGCG
TTAGAGAGCTTTTGAAGTTTGGTCAGGATATTGCCTGCTATGTTCCCGAGAGTATTTTGGAGGAAATAAGAAATGAAAAA
AAAGATTAG

Upstream 100 bases:

>100_bases
GTTGTGTGCGAGACGGATAAGGCCGTTGAACTTCCAGAAGAAATTGCCTGTCTGGGTATCTGGAAGGAAAAGATTTATGG
AATTAGTAAGGTGACAGTCT

Downstream 100 bases:

>100_bases
ATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCCTTATTATATAGAGGTTC
CAGGTGGTTCGGAAGATATT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKALGHLENVEVVASHDELVVDVA
KRLGATFLVRGLRNASDLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
KD

Sequences:

>Translated_162_residues
MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKALGHLENVEVVASHDELVVDVA
KRLGATFLVRGLRNASDLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
KD
>Mature_161_residues
SDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAK
RLGATFLVRGLRNASDLQYEASFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEKK
D

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=150, Percent_Identity=36.6666666666667, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18515; Mature: 18384

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKAL
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHH
GHLENVEVVASHDELVVDVAKRLGATFLVRGLRNASDLQYEASFDYYNHQLSSDIETIYL
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCEEEEE
HSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEKKD
ECCCCEEEEECHHHHHHHHCCCCEEEECCHHHHHHHHHCCCC
>Mature Secondary Structure 
SDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQGFLPIENRKRGLEKAL
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHH
GHLENVEVVASHDELVVDVAKRLGATFLVRGLRNASDLQYEASFDYYNHQLSSDIETIYL
HHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCEEEEE
HSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEKKD
ECCCCEEEEECHHHHHHHHCCCCEEEECCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA