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The map label for this gene is coaE [H]

Identifier: 225861142

GI number: 225861142

Start: 1175177

End: 1175782

Strand: Reverse

Name: coaE [H]

Synonym: SPT_1232

Alternate gene names: 225861142

Gene position: 1175782-1175177 (Counterclockwise)

Preceding gene: 225861143

Following gene: 225861141

Centisome position: 55.67

GC content: 44.22

Gene sequence:

>606_bases
ATGAGAAAAATCATCGGAATCACTGGGGGAATTGCCTCTGGTAAGTCAACTGTGACAAATTTTCTAAGACAGCAAGGCTT
TCAAGTAGTGGATGCCGACGCAGTCGTCCACCAACTACAGAAATCTGGTGGTCGTCTGTTTGAGGCTCTAGTACAGCACT
TTGGGCAAGAAATCATTCTTGAAAACGGAGAACTCAATCGCCCTCTCCTAGCTAGTCTCATCTTTTCAAATCCTGAAGAG
CAAAAATGGTCTAAGCAAATTCAAGGGGAGATTATCCGTGAGGAACTGGCTACTTTGAGAGAACAGTTGGCTCAGACAGA
AGAGATTTTCTTCATGGATATTCCCCTACTTTTTGAGCAGGACTACAGCGATTGGTTTGCTGAGACTTGGTTGGTCTATG
TGGACCGAGATACCCAAGTAGAACGCTTAATGAAAAGGGACCAGTTGTCCAAAGATGAAGCTGAGTCTCGTCTGGCAGCC
CAGTGGCCTTTAGAAAAAAAGAAAGATTTGGCCAGCCAGGTTCTTGATAATAATGGCAATCAGAACCAGCTTCTTAATCA
AGTGCATATCCTTCTTGAGGGAGGTAGGCAAGATGACAGAGATTAA

Upstream 100 bases:

>100_bases
AGACTGGTCAAGAATGTGTACGCTGTGGTACCATCATTGAGAAAATTCAACTAGGCGGACGAGGCACCCACTTTTGTCCA
AACTGTCAAAGGAGGGACTG

Downstream 100 bases:

>100_bases
CTGGAAGGATAATCTGCGCATTGCCTGGTTTGGTAATTTTCTGACAGGAGCCAGTATTTCTTTGGTTGTACCTTTTATGC
CCATCTTCGTGGAAAATCTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKSGGRLFEALVQHFGQEIILENGELNRPLLASLIFSNPEE
QKWSKQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD

Sequences:

>Translated_201_residues
MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKSGGRLFEALVQHFGQEIILENGELNRPLLASLIFSNPEE
QKWSKQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD
>Mature_201_residues
MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKSGGRLFEALVQHFGQEIILENGELNRPLLASLIFSNPEE
QKWSKQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAA
QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=179, Percent_Identity=40.2234636871508, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI191252795, Length=179, Percent_Identity=40.2234636871508, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI110227607, Length=162, Percent_Identity=31.4814814814815, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI205277394, Length=162, Percent_Identity=31.4814814814815, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI110227605, Length=162, Percent_Identity=31.4814814814815, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI110227603, Length=162, Percent_Identity=31.4814814814815, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI110227601, Length=162, Percent_Identity=31.4814814814815, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1786292, Length=188, Percent_Identity=34.5744680851064, Blast_Score=113, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=39.8963730569948, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI25143409, Length=160, Percent_Identity=30, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=193, Percent_Identity=32.6424870466321, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644728, Length=179, Percent_Identity=35.195530726257, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24658602, Length=164, Percent_Identity=35.9756097560976, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23109; Mature: 23109

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKSGGRLFEALVQHFGQEIIL
CCCEEEECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHCCHHHHHHHHHHCCHHHHH
ENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQ
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHC
DYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAAQWPLEKKKDLASQVLDNNGN
CHHHHHHHHHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
QNQLLNQVHILLEGGRQDDRD
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKSGGRLFEALVQHFGQEIIL
CCCEEEECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHCCHHHHHHHHHHCCHHHHH
ENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQ
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHC
DYSDWFAETWLVYVDRDTQVERLMKRDQLSKDEAESRLAAQWPLEKKKDLASQVLDNNGN
CHHHHHHHHHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
QNQLLNQVHILLEGGRQDDRD
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]