| Definition | Streptococcus pneumoniae 70585, complete genome. |
|---|---|
| Accession | NC_012468 |
| Length | 2,184,682 |
Click here to switch to the map view.
The map label for this gene is uxaC
Identifier: 225859885
GI number: 225859885
Start: 2047655
End: 2049055
Strand: Reverse
Name: uxaC
Synonym: SP70585_2238
Alternate gene names: 225859885
Gene position: 2049055-2047655 (Counterclockwise)
Preceding gene: 225859886
Following gene: 225859884
Centisome position: 93.79
GC content: 41.54
Gene sequence:
>1401_bases ATGAGTTTTAACGATAAAAACTTTATGCTAAAAAATGAACCTGCTAAGGAGCTTTACGTGAAAATAGCAGAGCTACCTAT CTATGATTTTCATTGTCACTTGGATCCTAAGGAAATTTTTGAAGACAAGGTCTATGAAGATATTGTTGATTTGTGGCTAG GTGGAGATCACTATAAGTGGCGCTTGATGCGGGCTAATGGAATTTCAGAAGAAGAGATCACAGGATTTGCAAGTAAGTTA GATAAATTTAAAGCCTGGGCAAGAACTTTGGAACGTGCTTTTGGAAATCCTCTCTACCATTGGAGTCATTTGGAATTACG ACAAGTTTTTGGTATCGAGGAATTGCTGACGGAAGAAAATGCAGAGCGTCTCTATCATCAGCTCAATACCTATTTGCAAG AACATCAAATTAGTCCACGTAAGCTGATCGCTGATGCCAGAGTGGCCTTTATCGGGACAACTGACCATCCTCTTGATAAC CTAGAATGGCATAAGCGTTTGGCAGAAGATTCACCCATTGACACTGTAGTAGCGCCAACCTTCCGTCCAGATGAAGCCTT TATAGAACACAGAAATTTCAATTTATTTATTAAACGCTTGGAAGAAGTGACGGAGGTAGCAGTAAGAGACTTTGCCAGTT TTGTAGAGGCTTTGGGCCAACGAGTTTCCTATTTTGCTCAACATGGTTGCCGAGCAAGCGATATTAGTTTTACAGCTATT ACCTATGAAGAAGCTACACTTGAAGAACTGAATGATATTTTACTTGCTAGGATGGTAGGGAAAGAGGTCGGACAATCTGG GATCAATAAGTGGCAGACAGCTATTTTTAGAGAACTCTGTCGTATGTACAAGAAACATGGATTTGTCACACAAGTTCATT TTGGTGCCTTACGAAACAACCATACAGGACTGTTTGAAAAACTTGGAGCAGATGTAGGTGTAGATTCGATTGGAGACCAG ACGTGCTTGACGGGGAACTTGAATCGTTTGTTGGACAACTTGGTCAAGGAAAATGCCCTTCCAAAAATGATTTGGTACAA CCTTAATCCAGGCTACAATATTGCCCTAGCCAACACCTTAGCAAATTTCCAAGCCAATGAGGAAGGGCGTCGTAGTCAGT TGCAGTTTGGTGCGGGTTGGTGGTTTAACGATACCAAGCTAGGCATGATTGACCAGATGAATGCCTATGCCGAGCAAGGT ATGCTTGCTAATTTTGTAGGGATGTTGACAGATTCGCGTAGCTTCTTGTCCTACCAACGCCATGATTATTTCAGACGAAT TTTGGCGACCTATGTTGGCCAATGGATTGTGGATGAGGAAGTGCCTGAGGACTATGATCGCCTAGGTCAGTTTGTAGAAG CAATATCTTACTACAATGCCAAAGAGTTTTTTGAACAATAA
Upstream 100 bases:
>100_bases GTTGGAATTGGTTCGGCATTGGCGAGTCGGGTGCAGGCTGAGGGCTATGACAGTGTAACGTTGATTGCTCGTAGTTTTGT AGCAGCTTTGGAGGGATAAG
Downstream 100 bases:
>100_bases AGGAGAGTAAATCATGAAAATGTCATTTCGATGGTATGGAAAAAAAGACCCTGTGACACTTGAAGAGATTAAAGCAATTC CTGGCATGCAGGGAATTGTG
Product: glucuronate isomerase
Products: NA
Alternate protein names: Glucuronate isomerase; Uronic isomerase
Number of amino acids: Translated: 466; Mature: 465
Protein sequence:
>466_residues MSFNDKNFMLKNEPAKELYVKIAELPIYDFHCHLDPKEIFEDKVYEDIVDLWLGGDHYKWRLMRANGISEEEITGFASKL DKFKAWARTLERAFGNPLYHWSHLELRQVFGIEELLTEENAERLYHQLNTYLQEHQISPRKLIADARVAFIGTTDHPLDN LEWHKRLAEDSPIDTVVAPTFRPDEAFIEHRNFNLFIKRLEEVTEVAVRDFASFVEALGQRVSYFAQHGCRASDISFTAI TYEEATLEELNDILLARMVGKEVGQSGINKWQTAIFRELCRMYKKHGFVTQVHFGALRNNHTGLFEKLGADVGVDSIGDQ TCLTGNLNRLLDNLVKENALPKMIWYNLNPGYNIALANTLANFQANEEGRRSQLQFGAGWWFNDTKLGMIDQMNAYAEQG MLANFVGMLTDSRSFLSYQRHDYFRRILATYVGQWIVDEEVPEDYDRLGQFVEAISYYNAKEFFEQ
Sequences:
>Translated_466_residues MSFNDKNFMLKNEPAKELYVKIAELPIYDFHCHLDPKEIFEDKVYEDIVDLWLGGDHYKWRLMRANGISEEEITGFASKL DKFKAWARTLERAFGNPLYHWSHLELRQVFGIEELLTEENAERLYHQLNTYLQEHQISPRKLIADARVAFIGTTDHPLDN LEWHKRLAEDSPIDTVVAPTFRPDEAFIEHRNFNLFIKRLEEVTEVAVRDFASFVEALGQRVSYFAQHGCRASDISFTAI TYEEATLEELNDILLARMVGKEVGQSGINKWQTAIFRELCRMYKKHGFVTQVHFGALRNNHTGLFEKLGADVGVDSIGDQ TCLTGNLNRLLDNLVKENALPKMIWYNLNPGYNIALANTLANFQANEEGRRSQLQFGAGWWFNDTKLGMIDQMNAYAEQG MLANFVGMLTDSRSFLSYQRHDYFRRILATYVGQWIVDEEVPEDYDRLGQFVEAISYYNAKEFFEQ >Mature_465_residues SFNDKNFMLKNEPAKELYVKIAELPIYDFHCHLDPKEIFEDKVYEDIVDLWLGGDHYKWRLMRANGISEEEITGFASKLD KFKAWARTLERAFGNPLYHWSHLELRQVFGIEELLTEENAERLYHQLNTYLQEHQISPRKLIADARVAFIGTTDHPLDNL EWHKRLAEDSPIDTVVAPTFRPDEAFIEHRNFNLFIKRLEEVTEVAVRDFASFVEALGQRVSYFAQHGCRASDISFTAIT YEEATLEELNDILLARMVGKEVGQSGINKWQTAIFRELCRMYKKHGFVTQVHFGALRNNHTGLFEKLGADVGVDSIGDQT CLTGNLNRLLDNLVKENALPKMIWYNLNPGYNIALANTLANFQANEEGRRSQLQFGAGWWFNDTKLGMIDQMNAYAEQGM LANFVGMLTDSRSFLSYQRHDYFRRILATYVGQWIVDEEVPEDYDRLGQFVEAISYYNAKEFFEQ
Specific function: Hexuronate conversion to KDG. [C]
COG id: COG1904
COG function: function code G; Glucuronate isomerase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the uronate isomerase family
Homologues:
Organism=Escherichia coli, GI2367192, Length=465, Percent_Identity=44.7311827956989, Blast_Score=414, Evalue=1e-117,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): UXAC_STRP7 (C1CAV7)
Other databases:
- EMBL: CP000918 - RefSeq: YP_002741395.1 - EnsemblBacteria: EBSTRT00000073495 - GeneID: 7683940 - GenomeReviews: CP000918_GR - KEGG: snm:SP70585_2238 - GeneTree: EBGT00050000027634 - ProtClustDB: PRK02925 - BioCyc: SPNE488221:SP70585_2238-MONOMER - HAMAP: MF_00675 - InterPro: IPR003766 - InterPro: IPR023177 - Gene3D: G3DSA:1.10.2020.10
Pfam domain/function: PF02614 UxaC
EC number: =5.3.1.12
Molecular weight: Translated: 54126; Mature: 53994
Theoretical pI: Translated: 5.02; Mature: 5.02
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFNDKNFMLKNEPAKELYVKIAELPIYDFHCHLDPKEIFEDKVYEDIVDLWLGGDHYKW CCCCCCCCEECCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEE RLMRANGISEEEITGFASKLDKFKAWARTLERAFGNPLYHWSHLELRQVFGIEELLTEEN EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHH AERLYHQLNTYLQEHQISPRKLIADARVAFIGTTDHPLDNLEWHKRLAEDSPIDTVVAPT HHHHHHHHHHHHHHHCCCHHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCCCCCEECCC FRPDEAFIEHRNFNLFIKRLEEVTEVAVRDFASFVEALGQRVSYFAQHGCRASDISFTAI CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE TYEEATLEELNDILLARMVGKEVGQSGINKWQTAIFRELCRMYKKHGFVTQVHFGALRNN EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCC HTGLFEKLGADVGVDSIGDQTCLTGNLNRLLDNLVKENALPKMIWYNLNPGYNIALANTL CCHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEHHHH ANFQANEEGRRSQLQFGAGWWFNDTKLGMIDQMNAYAEQGMLANFVGMLTDSRSFLSYQR HHCCCCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHH HDYFRRILATYVGQWIVDEEVPEDYDRLGQFVEAISYYNAKEFFEQ HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHCC >Mature Secondary Structure SFNDKNFMLKNEPAKELYVKIAELPIYDFHCHLDPKEIFEDKVYEDIVDLWLGGDHYKW CCCCCCCEECCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEE RLMRANGISEEEITGFASKLDKFKAWARTLERAFGNPLYHWSHLELRQVFGIEELLTEEN EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHH AERLYHQLNTYLQEHQISPRKLIADARVAFIGTTDHPLDNLEWHKRLAEDSPIDTVVAPT HHHHHHHHHHHHHHHCCCHHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCCCCCEECCC FRPDEAFIEHRNFNLFIKRLEEVTEVAVRDFASFVEALGQRVSYFAQHGCRASDISFTAI CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE TYEEATLEELNDILLARMVGKEVGQSGINKWQTAIFRELCRMYKKHGFVTQVHFGALRNN EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCC HTGLFEKLGADVGVDSIGDQTCLTGNLNRLLDNLVKENALPKMIWYNLNPGYNIALANTL CCHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEHHHH ANFQANEEGRRSQLQFGAGWWFNDTKLGMIDQMNAYAEQGMLANFVGMLTDSRSFLSYQR HHCCCCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHH HDYFRRILATYVGQWIVDEEVPEDYDRLGQFVEAISYYNAKEFFEQ HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA