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The map label for this gene is yidJ [C]

Identifier: 225859570

GI number: 225859570

Start: 1727658

End: 1729133

Strand: Reverse

Name: yidJ [C]

Synonym: SP70585_1861

Alternate gene names: 225859570

Gene position: 1729133-1727658 (Counterclockwise)

Preceding gene: 225859571

Following gene: 225859569

Centisome position: 79.15

GC content: 35.91

Gene sequence:

>1476_bases
ATGGTTCAGACAAAACAGCCAAATATTATTTTGATTGTTGTAGATCAAATGAGAGCAGACGCCTTATCCTTGAATAGTAA
GGATAAGCTAGTTAGCACTCCAACATTAGATATGATGGCTAGTGTAGGTTATAATTTTGAAAATGCCTATTCTCCAGTTC
CTTCTTGCGTTCCTGCTAGGGCAGCTTTATTGACTGGCTTAGACCAAGATAAAAGTGGACGTGTTGGTTATCAAGATGAG
GTGCCTTGGAATTTTACTAATACTCTTCCAAAAGTCTTTAAAGATATGGGTTATCAAACAGAGTGTATTGGTAAGATGCA
TGTTTTTCCTTCCAGACAGAGACTTGGGTTTGATCATGTCTTACTTCACGATGGGTATCTACATGTTGATAGAAAGTATG
ATAAGGCTTATGGAAGTCAATTTGATTATGCTAGTGACTATCTAGCCTTTTTAAAGGGTAAAGTTGGTTATGATGTTGAT
TTGATTGATGACGGAATGGATTGTAATTCTTGGGAAGCTAGACCTTGGGATAAAGATGAGAAGTTACATCCAACAAACTG
GGTTGTGAGTGAGTCTATTTCATTTTTACAAAGAAGAGATCCAACGGTTCCTTTTTTTCTCAAAATGTCTTTTGAAAAAC
CACATGCTCCATTAAATCCCCCAAAATACTATTTTGATATGTATATGGAACGCTTGCCTCAATTTCTCGATTTGCATATC
GGGAATTGGGAAGTATTAGAAAAGCAAATTCCGTCTATTTATGCTTTAAGAGGGAAATTAAAGGAAGATGATCAAAGAAG
AATGGTTGCTGCTTATTTTGGATTGATTACTCATATAGACCATCAAATTAGTCGCTTTTTGACTGCCCTAAAAGAATTTC
GTCATGATAAAGATACGATTATCTGGTTTGTTTCGGATCATGGAGATCAGCTTGGTGAACATTATCTGTTTAGAAAGGGA
TATCCTTATCAGGGAAGTATCCACATTCCTTCGTTTATTTACGATCCGGCTGGATTGATAGCTGGTAATAGGGGAACAAT
CAAGCAATTAGTGAAAATTCAAGATATTTTTCCTTCACTCGTGGATTTGGCAGGAGGAACTACTACAGATGAACTAGATG
GACGGAGTGTTAAGAATTTATTATTTGGACAGTACGAGGGGTGGCGAACAGAATTTCATGGAGAACATGCTTTAGGAAAA
GATTCTAGTCAATATATCTTGACAGACCAGTGGAAATTTATCTGGTTTCCTGTTTTAAATCATTATCAGTTATTTGATAT
GAAAAAAGATCCGCATGAAATGAATGATTTGTATCCAAGTGAAAAATACCAACCTATTGTTCGTCAGATGAAGAAAAAAT
TAGTAGACTTTCTTAGATATAGAGAAGAAGGTTTTGTTGTGGATGAAGAGTTAGTTCCTGTTGAACTTTCTAAAATAACG
CCAACTCTAACGAAAACGAGGGATAGTCAATCATGA

Upstream 100 bases:

>100_bases
AGAATGTTATTGTTTTATATAGAGAGATTGATATAGAAAGGGGTGCAGTAAAGGTAGATATCTTCTTGTGCCTCTTTTGC
CATATTAGAAAGGAGATTTT

Downstream 100 bases:

>100_bases
AAATGAAAAAAATCAAGGGTGGGACATTTATGATGGGAACAAATTCTGAAGAGGGCTTTTTAGATGATTTTGAAGGTCCT
CAAGTCGCTGTTAGTGTAAA

Product: arylsulfatase

Products: NA

Alternate protein names: Cys-type sulfatase [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGYNFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDE
VPWNFTNTLPKVFKDMGYQTECIGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPLNPPKYYFDMYMERLPQFLDLHI
GNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLITHIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKG
YPYQGSIHIPSFIYDPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEFHGEHALGK
DSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQMKKKLVDFLRYREEGFVVDEELVPVELSKIT
PTLTKTRDSQS

Sequences:

>Translated_491_residues
MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGYNFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDE
VPWNFTNTLPKVFKDMGYQTECIGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPLNPPKYYFDMYMERLPQFLDLHI
GNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLITHIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKG
YPYQGSIHIPSFIYDPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEFHGEHALGK
DSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQMKKKLVDFLRYREEGFVVDEELVPVELSKIT
PTLTKTRDSQS
>Mature_491_residues
MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGYNFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDE
VPWNFTNTLPKVFKDMGYQTECIGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPLNPPKYYFDMYMERLPQFLDLHI
GNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLITHIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKG
YPYQGSIHIPSFIYDPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEFHGEHALGK
DSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQMKKKLVDFLRYREEGFVVDEELVPVELSKIT
PTLTKTRDSQS

Specific function: Has sulfatase activity toward para-nitrophenyl sulfate, which is increased in presence of calcium ion [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI39930577, Length=492, Percent_Identity=25.2032520325203, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI109389362, Length=518, Percent_Identity=25.0965250965251, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI4557659, Length=405, Percent_Identity=27.4074074074074, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI262118210, Length=323, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790112, Length=470, Percent_Identity=26.1702127659574, Blast_Score=119, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24666175, Length=411, Percent_Identity=25.0608272506083, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24666109, Length=391, Percent_Identity=25.0639386189258, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281366397, Length=451, Percent_Identity=24.8337028824834, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281366395, Length=451, Percent_Identity=24.8337028824834, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666163, Length=451, Percent_Identity=24.8337028824834, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 56988; Mature: 56988

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGYNFENAYSPVPSCVPAR
CCCCCCCCEEEEEECCCCCHHHCCCCCCCEECCCHHHHHHHCCCCCCCCCCCCCCHHHHH
AALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTECIGKMHVFPSRQRLGFDHV
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHEECCCCHHHCCCCEE
LLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVDLIDDGMDCNSWEARPWDKDE
EEECCEEEECCHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCC
KLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPLNPPKYYFDMYMERLPQFLDLHI
CCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHEECC
GNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLITHIDHQISRFLTALKEFRHDKDTI
CCHHHHHHHCCHHEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
IWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIYDPAGLIAGNRGTIKQLVKIQDIFPSL
EEEEECCCHHHHHHHHHHCCCCCCCCEECCHHEECCCHHEECCCHHHHHHHHHHHHHHHH
VDLAGGTTTDELDGRSVKNLLFGQYEGWRTEFHGEHALGKDSSQYILTDQWKFIWFPVLN
HHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEHHC
HYQLFDMKKDPHEMNDLYPSEKYQPIVRQMKKKLVDFLRYREEGFVVDEELVPVELSKIT
CEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEHHHCC
PTLTKTRDSQS
CHHHCCCCCCC
>Mature Secondary Structure
MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGYNFENAYSPVPSCVPAR
CCCCCCCCEEEEEECCCCCHHHCCCCCCCEECCCHHHHHHHCCCCCCCCCCCCCCHHHHH
AALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTECIGKMHVFPSRQRLGFDHV
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHEECCCCHHHCCCCEE
LLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVDLIDDGMDCNSWEARPWDKDE
EEECCEEEECCHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCC
KLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPLNPPKYYFDMYMERLPQFLDLHI
CCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCHHHHEECC
GNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLITHIDHQISRFLTALKEFRHDKDTI
CCHHHHHHHCCHHEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
IWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIYDPAGLIAGNRGTIKQLVKIQDIFPSL
EEEEECCCHHHHHHHHHHCCCCCCCCEECCHHEECCCHHEECCCHHHHHHHHHHHHHHHH
VDLAGGTTTDELDGRSVKNLLFGQYEGWRTEFHGEHALGKDSSQYILTDQWKFIWFPVLN
HHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEEHHC
HYQLFDMKKDPHEMNDLYPSEKYQPIVRQMKKKLVDFLRYREEGFVVDEELVPVELSKIT
CEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEHHHCC
PTLTKTRDSQS
CHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA