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The map label for this gene is mmgC [H]

Identifier: 225686848

GI number: 225686848

Start: 1063361

End: 1064503

Strand: Reverse

Name: mmgC [H]

Synonym: BMEA_B1088

Alternate gene names: 225686848

Gene position: 1064503-1063361 (Counterclockwise)

Preceding gene: 225686853

Following gene: 225686847

Centisome position: 89.79

GC content: 54.68

Gene sequence:

>1143_bases
ATGATCCGCGATCCGGAAACACTCGATGCGCTTGTCACAACGGTTCGGCGTTTCGTGCGCGAACGTCTGGTACCGGCGGA
AAGTCGCGTCGAAGAGACGAACCGTATTCCTGATGACATCATTGAAGAAATGCGGGCCATGGGCCTCTTTGGTTTGTCGA
TCCCGGAAGAGTATGGCGGTCTTGGCCTGACGATGGAAGAGGAAGTCCGTGTCGGTTTTGAACTTGGATATACCTCACCA
GCCTTTCGCTCCGTCATTGGTACCAATAATGGCATCGGCTCTCAGGGCATCATTGCCGATGGCACAGACGACCAGAAGAA
ATATTGGCTTCCACGGCTGGCCAGCGGCGGGATAATTGGTTCATTCGCATTGACAGAGCCTGATGTCGGTTCGGATGCCG
GTGCAGTACGCACCACTGCCGAACGCGACGGAGACAGCTATATCATCAACGGCACGAAGCGCTTCATTACCAATGCGCCG
GTTGCCGGAGTTTTCACGCTCATGGCTCGTACGGGTGGTTCGGGCCCATCGGGAATCAGCGCCTTTCTGGCGGAAAGGGA
TTTGCCCGGTCTCACGGTCGGAACACCCGACCACAAAATGGGCCAGAGAGGCACCCAAACCTGCGATGTCTATCTTGAGA
ATGTACGCGTTCCTGCTACAAGCATAATTGGCGGGGTCGAAGGACGCGGTTTCAAGACCGCTATGAAAGTACTCAATCGC
GGGCGTCTTCATATATCGTCCGTCTGCGCCGGTACGGCGGAGCGTCCGATTGAGGAATCTGTCGGCTTTGCCGGCAGCCG
CGTACAGTTTGGCAAACGTATCGCCGAACATCAGATGATTCAGGCGATGCTGGCCGATATGAGCACAGAAGCCTATGCGG
GGCGTTGCATGGTTCTTGATGCCGCACGGGCCTTTGATGAAAGCAACGTCGATATCATTCGCAAAGCTGCAAGCTGCAAG
TTGTTTTGTTCCGAAATGGTTGGAAGGGTTGCAGACAATGCCGTGCAGATACACGGCGGCTCCGGATATATGCAGAACTA
TCCGGTCGAGCACTTCTATCGCGATGTACGTTTGTTCCGCCTCTATGAGGGAACCTCGCAAATCCAGCGAATTATCATAG
CGCGCGAAATGATAAGGGAGTGA

Upstream 100 bases:

>100_bases
CAATATTCTATGAAACATTCGCTTAGCAATAGGAGATTTCAGCAATCGAAAAGCGTTTCCGCCCCGGGCAGGAAACTGTT
CGATTTCTTGGGGGAAGTTG

Downstream 100 bases:

>100_bases
ACCAGAAAGCACGCAAAATGCAGCGGAAAGAAAAACATCTATACGCCTGAAACAACTGTCCGACGAGAATTACCGGCATA
GGAAACAAGCCGGTTTCGAT

Product: acyl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MIRDPETLDALVTTVRRFVRERLVPAESRVEETNRIPDDIIEEMRAMGLFGLSIPEEYGGLGLTMEEEVRVGFELGYTSP
AFRSVIGTNNGIGSQGIIADGTDDQKKYWLPRLASGGIIGSFALTEPDVGSDAGAVRTTAERDGDSYIINGTKRFITNAP
VAGVFTLMARTGGSGPSGISAFLAERDLPGLTVGTPDHKMGQRGTQTCDVYLENVRVPATSIIGGVEGRGFKTAMKVLNR
GRLHISSVCAGTAERPIEESVGFAGSRVQFGKRIAEHQMIQAMLADMSTEAYAGRCMVLDAARAFDESNVDIIRKAASCK
LFCSEMVGRVADNAVQIHGGSGYMQNYPVEHFYRDVRLFRLYEGTSQIQRIIIAREMIRE

Sequences:

>Translated_380_residues
MIRDPETLDALVTTVRRFVRERLVPAESRVEETNRIPDDIIEEMRAMGLFGLSIPEEYGGLGLTMEEEVRVGFELGYTSP
AFRSVIGTNNGIGSQGIIADGTDDQKKYWLPRLASGGIIGSFALTEPDVGSDAGAVRTTAERDGDSYIINGTKRFITNAP
VAGVFTLMARTGGSGPSGISAFLAERDLPGLTVGTPDHKMGQRGTQTCDVYLENVRVPATSIIGGVEGRGFKTAMKVLNR
GRLHISSVCAGTAERPIEESVGFAGSRVQFGKRIAEHQMIQAMLADMSTEAYAGRCMVLDAARAFDESNVDIIRKAASCK
LFCSEMVGRVADNAVQIHGGSGYMQNYPVEHFYRDVRLFRLYEGTSQIQRIIIAREMIRE
>Mature_380_residues
MIRDPETLDALVTTVRRFVRERLVPAESRVEETNRIPDDIIEEMRAMGLFGLSIPEEYGGLGLTMEEEVRVGFELGYTSP
AFRSVIGTNNGIGSQGIIADGTDDQKKYWLPRLASGGIIGSFALTEPDVGSDAGAVRTTAERDGDSYIINGTKRFITNAP
VAGVFTLMARTGGSGPSGISAFLAERDLPGLTVGTPDHKMGQRGTQTCDVYLENVRVPATSIIGGVEGRGFKTAMKVLNR
GRLHISSVCAGTAERPIEESVGFAGSRVQFGKRIAEHQMIQAMLADMSTEAYAGRCMVLDAARAFDESNVDIIRKAASCK
LFCSEMVGRVADNAVQIHGGSGYMQNYPVEHFYRDVRLFRLYEGTSQIQRIIIAREMIRE

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=354, Percent_Identity=41.2429378531073, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=38.031914893617, Blast_Score=251, Evalue=6e-67,
Organism=Homo sapiens, GI4501859, Length=369, Percent_Identity=34.6883468834688, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI187960098, Length=369, Percent_Identity=36.0433604336043, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI76496475, Length=379, Percent_Identity=36.6754617414248, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI4557235, Length=375, Percent_Identity=37.0666666666667, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI4557231, Length=369, Percent_Identity=36.0433604336043, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI4501857, Length=388, Percent_Identity=33.7628865979381, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI226958412, Length=370, Percent_Identity=31.8918918918919, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI7656849, Length=363, Percent_Identity=33.3333333333333, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI226958414, Length=367, Percent_Identity=32.1525885558583, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI4503943, Length=391, Percent_Identity=29.6675191815857, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI38505218, Length=395, Percent_Identity=27.5949367088608, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI7669494, Length=379, Percent_Identity=29.287598944591, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=28.0397022332506, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI211971008, Length=403, Percent_Identity=28.0397022332506, Blast_Score=135, Evalue=9e-32,
Organism=Escherichia coli, GI1786223, Length=358, Percent_Identity=28.4916201117318, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI87081958, Length=380, Percent_Identity=30.2631578947368, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87081702, Length=341, Percent_Identity=29.9120234604106, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082384, Length=293, Percent_Identity=23.8907849829352, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=376, Percent_Identity=37.2340425531915, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI17570075, Length=373, Percent_Identity=36.4611260053619, Blast_Score=243, Evalue=9e-65,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=36.3881401617251, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=36.2433862433862, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17506239, Length=363, Percent_Identity=36.9146005509642, Blast_Score=238, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17534899, Length=369, Percent_Identity=36.0433604336043, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=32.3529411764706, Blast_Score=214, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17533517, Length=370, Percent_Identity=30.2702702702703, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71985192, Length=300, Percent_Identity=38, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71990804, Length=296, Percent_Identity=35.1351351351351, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=39.3939393939394, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=30.0531914893617, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=33.0882352941176, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17505929, Length=383, Percent_Identity=28.7206266318538, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=28.2321899736148, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=32.7800829875519, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17562446, Length=364, Percent_Identity=29.1208791208791, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17531913, Length=197, Percent_Identity=31.4720812182741, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=274, Percent_Identity=26.6423357664234, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=274, Percent_Identity=26.6423357664234, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281363737, Length=377, Percent_Identity=36.0742705570292, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=38.031914893617, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24660351, Length=371, Percent_Identity=36.1185983827493, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24666513, Length=363, Percent_Identity=35.8126721763085, Blast_Score=231, Evalue=5e-61,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=34.5744680851064, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI21355753, Length=368, Percent_Identity=31.25, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI19920834, Length=391, Percent_Identity=29.6675191815857, Blast_Score=145, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 41391; Mature: 41391

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRDPETLDALVTTVRRFVRERLVPAESRVEETNRIPDDIIEEMRAMGLFGLSIPEEYGG
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHCC
LGLTMEEEVRVGFELGYTSPAFRSVIGTNNGIGSQGIIADGTDDQKKYWLPRLASGGIIG
CCCCCHHHHHEEEEECCCCHHHHHHHCCCCCCCCCCEEECCCCCHHHHHCCHHCCCCEEE
SFALTEPDVGSDAGAVRTTAERDGDSYIINGTKRFITNAPVAGVFTLMARTGGSGPSGIS
EEECCCCCCCCCCCCEEEHHCCCCCEEEECCHHHHHCCCCHHHHHHHHHHCCCCCCHHHH
AFLAERDLPGLTVGTPDHKMGQRGTQTCDVYLENVRVPATSIIGGVEGRGFKTAMKVLNR
HHHHHCCCCCCEECCCCHHHCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHC
GRLHISSVCAGTAERPIEESVGFAGSRVQFGKRIAEHQMIQAMLADMSTEAYAGRCMVLD
CCEEEHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEE
AARAFDESNVDIIRKAASCKLFCSEMVGRVADNAVQIHGGSGYMQNYPVEHFYRDVRLFR
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHH
LYEGTSQIQRIIIAREMIRE
HHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRDPETLDALVTTVRRFVRERLVPAESRVEETNRIPDDIIEEMRAMGLFGLSIPEEYGG
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHCC
LGLTMEEEVRVGFELGYTSPAFRSVIGTNNGIGSQGIIADGTDDQKKYWLPRLASGGIIG
CCCCCHHHHHEEEEECCCCHHHHHHHCCCCCCCCCCEEECCCCCHHHHHCCHHCCCCEEE
SFALTEPDVGSDAGAVRTTAERDGDSYIINGTKRFITNAPVAGVFTLMARTGGSGPSGIS
EEECCCCCCCCCCCCEEEHHCCCCCEEEECCHHHHHCCCCHHHHHHHHHHCCCCCCHHHH
AFLAERDLPGLTVGTPDHKMGQRGTQTCDVYLENVRVPATSIIGGVEGRGFKTAMKVLNR
HHHHHCCCCCCEECCCCHHHCCCCCHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHC
GRLHISSVCAGTAERPIEESVGFAGSRVQFGKRIAEHQMIQAMLADMSTEAYAGRCMVLD
CCEEEHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEE
AARAFDESNVDIIRKAASCKLFCSEMVGRVADNAVQIHGGSGYMQNYPVEHFYRDVRLFR
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHH
LYEGTSQIQRIIIAREMIRE
HHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]