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The map label for this gene is dadA

Identifier: 225686683

GI number: 225686683

Start: 888123

End: 889373

Strand: Direct

Name: dadA

Synonym: BMEA_B0906

Alternate gene names: 225686683

Gene position: 888123-889373 (Clockwise)

Preceding gene: 225686682

Following gene: 225686686

Centisome position: 74.91

GC content: 61.15

Gene sequence:

>1251_bases
ATGCAGATCACTATTCTCGGTAGCGGCGTCATCGGCGTTACGACGGCCTACTATCTCGCCAAGCTCGGCCATGAAGTAAC
GGTCATCGACCGTGAAGAAGGCCCGGCGCTGGAAACCTCCTTCGCCAATGCAGGTCAGGTTTCGCCTGGCTATGCGTCCC
CCTGGGCTGCCCCCGGCATTCCCCTGAAGGCGGCCAAGTGGCTCTTTCAGAAACATGCCCCGCTCATTCTCCGCCTCACC
ACCGATCCGGTACAATATCGCTGGCTGCTGCAGATGCTCGCCAACTGCACCGACAGCCGGTACAAGATCAACAAGACGCG
CATGGTGCGCGTGGCCGAATATAGCCGCGATTGCCTGATCGAGTTGCGCAAGGATACCGGCATTGAATATGACCAGCGCT
CGCAGGGTACCTTGCAGCTTTTCCGCGAGCAATACCAGCTCGACGGCATTGGCAAGGATATCGAGGTTCTGCGTCAGGAC
GGCGTACCGTTCGAGGTGCTCGACCGCGACGGATGCGTGAACGTGGAGCCGGCGCTTGCCCATGCGAAGGACAAGTTCGT
CGGCGGCCTGCGCCTGCCGAACGACGAGACCGGTGACTGTTTCAAATTCACCAATGCCTTGGCGAAGATTGCCGAAGGGC
TGGGCGTGAAGTTCCGCTTCGGCGTCAACATCAAGTCGCTGCTCATGTCGGGCGGCAAGATTTCCGGCGTGGAGACCTCT
GAGGGCATCGTCACCGCCGAACGCTATGTCGTGGCGCTTGGCAGCTATACGCCGGCACTCATCAAGGCGCTTGGCCTCAA
CGCCCCGATCTATCCGGTGAAGGGTTATTCCATCACCGCACCGATCGTCGATGAAAGCCGCGCACCGGTTTCAACCGTTC
TGGATGAAAGCTACAAGATCGCCATCACCCGCCTCGGCGACCGCATCCGCGTCGGCGGCATGGCGGAAGTGTCAGGCTTT
ACCGATGACCTGCCCGCCGCGCGCCGCGCCACACTCGACCTGTCGGTGACAGATCTCTTCCCCGGCGGCGATCTCAAGGC
TGCAACCTTCTGGTCGGGCCTGCGCCCCATGACACCGGATTCCACGCCTATCATCGGCGGCACGCGCTATGACAACCTGT
TCATCAATGCAGGCCACGGTACGCTCGGCTGGACCATGGCCTGCGGCTCCGGCCGCCTGCTTGCCGATCTGATTTCCGGC
AACAAGGCGGATATCCGCGCCGACGATCTGGGCATTGCGCGCTATAATTAA

Upstream 100 bases:

>100_bases
CTATGAAATTCTGACTGCGCTTGGCAACCGTTATGCGCGCGTTTACGTTTACGTGAATGGCGGTGGCACCAGCACAACAG
CATAACCACGAGAGGCGTAT

Downstream 100 bases:

>100_bases
TCCTGTACCGGGTCGCCCTTTTCCCACGGGCGACCCACACTTTCAGAAGCTCGGCGGCGTGCAGGCGCTGACGATTTCAC
AAGGGGCCGGCCCCACGCAG

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MQITILGSGVIGVTTAYYLAKLGHEVTVIDREEGPALETSFANAGQVSPGYASPWAAPGIPLKAAKWLFQKHAPLILRLT
TDPVQYRWLLQMLANCTDSRYKINKTRMVRVAEYSRDCLIELRKDTGIEYDQRSQGTLQLFREQYQLDGIGKDIEVLRQD
GVPFEVLDRDGCVNVEPALAHAKDKFVGGLRLPNDETGDCFKFTNALAKIAEGLGVKFRFGVNIKSLLMSGGKISGVETS
EGIVTAERYVVALGSYTPALIKALGLNAPIYPVKGYSITAPIVDESRAPVSTVLDESYKIAITRLGDRIRVGGMAEVSGF
TDDLPAARRATLDLSVTDLFPGGDLKAATFWSGLRPMTPDSTPIIGGTRYDNLFINAGHGTLGWTMACGSGRLLADLISG
NKADIRADDLGIARYN

Sequences:

>Translated_416_residues
MQITILGSGVIGVTTAYYLAKLGHEVTVIDREEGPALETSFANAGQVSPGYASPWAAPGIPLKAAKWLFQKHAPLILRLT
TDPVQYRWLLQMLANCTDSRYKINKTRMVRVAEYSRDCLIELRKDTGIEYDQRSQGTLQLFREQYQLDGIGKDIEVLRQD
GVPFEVLDRDGCVNVEPALAHAKDKFVGGLRLPNDETGDCFKFTNALAKIAEGLGVKFRFGVNIKSLLMSGGKISGVETS
EGIVTAERYVVALGSYTPALIKALGLNAPIYPVKGYSITAPIVDESRAPVSTVLDESYKIAITRLGDRIRVGGMAEVSGF
TDDLPAARRATLDLSVTDLFPGGDLKAATFWSGLRPMTPDSTPIIGGTRYDNLFINAGHGTLGWTMACGSGRLLADLISG
NKADIRADDLGIARYN
>Mature_416_residues
MQITILGSGVIGVTTAYYLAKLGHEVTVIDREEGPALETSFANAGQVSPGYASPWAAPGIPLKAAKWLFQKHAPLILRLT
TDPVQYRWLLQMLANCTDSRYKINKTRMVRVAEYSRDCLIELRKDTGIEYDQRSQGTLQLFREQYQLDGIGKDIEVLRQD
GVPFEVLDRDGCVNVEPALAHAKDKFVGGLRLPNDETGDCFKFTNALAKIAEGLGVKFRFGVNIKSLLMSGGKISGVETS
EGIVTAERYVVALGSYTPALIKALGLNAPIYPVKGYSITAPIVDESRAPVSTVLDESYKIAITRLGDRIRVGGMAEVSGF
TDDLPAARRATLDLSVTDLFPGGDLKAATFWSGLRPMTPDSTPIIGGTRYDNLFINAGHGTLGWTMACGSGRLLADLISG
NKADIRADDLGIARYN

Specific function: Oxidative deamination of D-amino acids

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787438, Length=417, Percent_Identity=58.273381294964, Blast_Score=510, Evalue=1e-146,
Organism=Drosophila melanogaster, GI20130091, Length=420, Percent_Identity=23.0952380952381, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DADA_BRUA1 (B2SDA2)

Other databases:

- EMBL:   CP000888
- RefSeq:   YP_001932252.1
- ProteinModelPortal:   B2SDA2
- GeneID:   6326075
- GenomeReviews:   CP000888_GR
- KEGG:   bmc:BAbS19_II02950
- HOGENOM:   HBG729204
- OMA:   WQMLQNC
- ProtClustDB:   PRK00711
- HAMAP:   MF_01202
- InterPro:   IPR023080
- InterPro:   IPR006076

Pfam domain/function: PF01266 DAO

EC number: =1.4.99.1

Molecular weight: Translated: 45110; Mature: 45110

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITILGSGVIGVTTAYYLAKLGHEVTVIDREEGPALETSFANAGQVSPGYASPWAAPGI
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCC
PLKAAKWLFQKHAPLILRLTTDPVQYRWLLQMLANCTDSRYKINKTRMVRVAEYSRDCLI
CHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEECHHEEEEEHHCCCHHEE
ELRKDTGIEYDQRSQGTLQLFREQYQLDGIGKDIEVLRQDGVPFEVLDRDGCVNVEPALA
EEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCCCCCHHHH
HAKDKFVGGLRLPNDETGDCFKFTNALAKIAEGLGVKFRFGVNIKSLLMSGGKISGVETS
HHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCEECCCCCC
EGIVTAERYVVALGSYTPALIKALGLNAPIYPVKGYSITAPIVDESRAPVSTVLDESYKI
CCEEEEEEEEEEECCCCHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCHHHHHCCCEEE
AITRLGDRIRVGGMAEVSGFTDDLPAARRATLDLSVTDLFPGGDLKAATFWSGLRPMTPD
EEEECCCEEEECCCCCCCCCCCCCCCHHHEEEEEEEEECCCCCCCCHHHHHCCCCCCCCC
STPIIGGTRYDNLFINAGHGTLGWTMACGSGRLLADLISGNKADIRADDLGIARYN
CCCEECCCEECEEEEECCCCCCEEEEECCCCCCHHHHHCCCCCCEEECCCEEEECC
>Mature Secondary Structure
MQITILGSGVIGVTTAYYLAKLGHEVTVIDREEGPALETSFANAGQVSPGYASPWAAPGI
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCC
PLKAAKWLFQKHAPLILRLTTDPVQYRWLLQMLANCTDSRYKINKTRMVRVAEYSRDCLI
CHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEECHHEEEEEHHCCCHHEE
ELRKDTGIEYDQRSQGTLQLFREQYQLDGIGKDIEVLRQDGVPFEVLDRDGCVNVEPALA
EEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCCCCCCCHHHH
HAKDKFVGGLRLPNDETGDCFKFTNALAKIAEGLGVKFRFGVNIKSLLMSGGKISGVETS
HHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCEECCCCCC
EGIVTAERYVVALGSYTPALIKALGLNAPIYPVKGYSITAPIVDESRAPVSTVLDESYKI
CCEEEEEEEEEEECCCCHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCHHHHHCCCEEE
AITRLGDRIRVGGMAEVSGFTDDLPAARRATLDLSVTDLFPGGDLKAATFWSGLRPMTPD
EEEECCCEEEECCCCCCCCCCCCCCCHHHEEEEEEEEECCCCCCCCHHHHHCCCCCCCCC
STPIIGGTRYDNLFINAGHGTLGWTMACGSGRLLADLISGNKADIRADDLGIARYN
CCCEECCCEECEEEEECCCCCCEEEEECCCCCCHHHHHCCCCCCEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA